Effect of Turmeric on Pruritus in Hemodialysis Patients

• Sponsor: Shiraz University of Medical Sciences (Other)
• Overall Status: Completed
• CT.gov ID: NCT01037595
• Collaborator: (none)
• Enrollment: 60
• Location: 1
• Arms: 2
• Duration (Months): 3
• Patients Per Site Per Month: 20.1

Study Details

Study Description

Brief Summary

The purpose of this study is to see whether turmeric can be effective in treatment of pruritus in hemodialysis patients.

Condition or Disease	Intervention/Treatment	Phase
End Stage Renal Failure	Drug: turmeric; Drug: placebo; Drug: turmeric	Early Phase 1

Detailed Description

pruritus is a common in hemodialysis patients and many treatment recommended for it . as turmeric has anti-inflammatory , anti-cytokine and anti-oxidant effect it may effective in treatment of uremic pruritus. thus we compared turmeric with placebo in this study

Study Design

• Study Type: Interventional
• Actual Enrollment: 60 participants
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Masking: Double (Participant, Investigator)
• Primary Purpose: Treatment
• Study Start Date: Sep 1, 2010
• Actual Primary Completion Date: Oct 1, 2010
• Actual Study Completion Date: Dec 1, 2010

Arms and Interventions

Arm	Intervention/Treatment
Experimental: turmeric turmeric 500 mg tid orally for 8 weeks	Drug: turmeric; turmeric 500 md tid orally for 8 weeks; Drug: turmeric; 500 mg tid orally for 8 weeks
Placebo Comparator: plasebo placebo tid orally for 8 weeks	Drug: placebo; placebo 3 time orally for 8 weeks

Outcome Measures

Primary Outcome Measures

1. improvement in pruritus [6 mo]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 70 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

• Hemodialysis for more than 3 months

• More than 18 years old

• Pruritus

Exclusion Criteria:

• Use other treatment for pruritus

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Shiraz University Hemodialysis Center	Shiraz	Fars	Iran, Islamic Republic of	098

Sponsors and Collaborators

• Shiraz University of Medical Sciences

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Maryam Pakfetrat, associated professor of shiraz Shiraz University of Medical Sciences, Shiraz University of Medical Sciences
• ClinicalTrials.gov Identifier: NCT01037595
• Other Study ID Numbers: 3441
• First Posted: Dec 23, 2009
• Last Update Posted: May 14, 2013
• Last Verified: May 1, 2013

• Keywords provided by Maryam Pakfetrat, associated professor of shiraz Shiraz University of Medical Sciences, Shiraz University of Medical Sciences: hemodialysis; turmeric; pruritus
• Additional relevant MeSH terms: Kidney Failure, Chronic; Turmeric extract

Study Results

No Results Posted as of May 14, 2013