SDF: Investigation of Endemic and Emerging Diseases in Populations of Homeless Households in Marseille.
Study Details
Study Description
Brief Summary
Hypothesis:
Homeless people have infections not diagnosed with a potential impact on their health status.
Main Purpose: Improve the etiological diagnosis of endemic and/or emerging pathologies among homeless people.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Detailed Description
In Marseilles, the population of homeless is estimated at 1500 individuals, including 800 usually sleeping in the street, 600 in foster homes and a hundred in the structures of care. The precarious living conditions of homeless persons promote the emergence or re-emergence of many communicable infectious diseases homeless people whose symptoms are often overlooked by the subject and rarely established etiologic diagnosis.
Among these diseases, frequently described in the literature are infestation by lice and infectious diseases that they transmit (Bartonella quintana), skin infections, hepatitis E and C and finally the infection with Tropheryma Whipplei. In this study we propose to systematically in homeless subject an etiological diagnosis of pathogens at the origin of these diseases (i) to improve knowledge (ii) to improve their management, (iii) to limit the contagion.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Other: Homeless people Populations of homeless households in Marseille. |
Other: Swabs skin, pharyngeal, and blood sample
Collection of one blood sample with a volume of 10 mL (2 tubes of blood 5 mL ) and 2 swabs ( throat and skin ).
Other: Collection of body lice
For the subjects infested with body lice , if they want, their underwear will be recovered and sent to the laboratory to measure the resistance to permethrin.
|
Outcome Measures
Primary Outcome Measures
- Percentage of subjects with an established microbiological diagnosis [3 years]
Secondary Outcome Measures
- Prevalence of skin infections [1 day]
- Prevalence of Tropheryma whipplei infections [1 day]
- Prevalence of infestation by body lice [1 day]
- Percentage of body lice resistant to permethrin [1 day]
- Prevalence of infections by Bartonella quintana [1 day]
- Prevalence of infection by hepatitis E and C [1 day]
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Homeless Subject on the day of the study in one of two shelters for homeless Marseille ( Madrague City and Forbin )
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Major subject ( > or equal to 18 years)
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Freely about having signed the written informed consent,
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About affiliated with a social security scheme
Exclusion Criteria:
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Minor Subjects ( < 18 years )
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Major subject under guardianship (L. 1121-8 )
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Subject privated of freedom or under court order (L. 1121-6 )
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Subject refusing to sign the informed consent form ,
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Subject not affiliated with a social security insurance
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Pregnant women , parturient or nursing (L. 1121-7 ) .
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Assistance Publique Hopitaux de Marseille | Marseille | France | 13354 |
Sponsors and Collaborators
- Assistance Publique Hopitaux De Marseille
Investigators
- Principal Investigator: Philippe BROUQUI, Pr, Assistance Publique - Hôpitaux de Marseille
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 2013-44