IMAGE-Endocarditis: Resonance Magnetic Imaging at the Acute Phase of Endocarditis

• Sponsor: Assistance Publique - Hôpitaux de Paris (Other)
• Overall Status: Completed
• CT.gov ID: NCT00144885
• Collaborator: (none)
• Enrollment: 150
• Location: 1
• Arm: 1
• Duration (Months): 42
• Patients Per Site Per Month: 3.6

Study Details

Study Description

Brief Summary

Patients with definite or possible infective endocarditis are included in this protocol, at the acute phase of the disease.

Condition or Disease	Intervention/Treatment	Phase
Endocarditis, Bacterial	Behavioral: Modification of therapy	N/A

Detailed Description

Patients with definite or possible infective endocarditis are included in this protocol, at the acute phase of the disease.

Resonance magnetic imaging (head and abdomen) will be performed systematically before Day 7.

The impact on the diagnosis and therapeutic options will be assessed, as compared to pre resonance magnetic nuclear (RMN) imaging declaration.

Study Design

• Study Type: Interventional
• Actual Enrollment: 150 participants
• Allocation: Non-Randomized
• Intervention Model: Single Group Assignment
• Masking: None (Open Label)
• Official Title: Resonance Magnetic Imaging at the Acute Phase of Endocarditis: Diagnostic and Therapeutic Impact
• Study Start Date: Jun 1, 2005
• Actual Primary Completion Date: Dec 1, 2008
• Actual Study Completion Date: Dec 1, 2008

Arms and Interventions

Arm	Intervention/Treatment
No Intervention: 1	Behavioral: Modification of therapy; Modification of the surgery date if adapted, modification of the antibiotics if adapted, based on RMI results

Outcome Measures

Primary Outcome Measures

1. Modification of therapeutic project [As soon as RMI is performed]

Secondary Outcome Measures

1. Modification of diagnostic classification (Duke modified criteria) [As soon as RMI is performed]

Eligibility Criteria

Criteria

• Ages Eligible for Study: N/A and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• Acute phase of infective endocarditis

Exclusion Criteria:

• Contra indication to RMN

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Hôpital Bichat Claude Bernard, 46 rue Henri Huchard	Paris		France	75877

Sponsors and Collaborators

• Assistance Publique - Hôpitaux de Paris

Investigators

• Principal Investigator: Xavier Duval, Hôpital Bichat, Assistance Publique Hôpitaux de Paris

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• ClinicalTrials.gov Identifier: NCT00144885
• Other Study ID Numbers: P040431
• First Posted: Sep 5, 2005
• Last Update Posted: Feb 12, 2009
• Last Verified: Sep 1, 2005

• Keywords provided by , ,: Endocarditis; RMI; Impact measure
• Additional relevant MeSH terms: Endocarditis, Bacterial; Endocarditis

Study Results

No Results Posted as of Feb 12, 2009