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Endogenous Endophthalmitis in the Inpatient Setting

Sponsor
Stanford University (Other)
Overall Status
Completed
CT.gov ID
NCT01323868
Collaborator
(none)
145
Enrollment
1
Location
35
Duration (Months)
4.1
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The purpose of this study is to determine the rate of endogenous endophthalmitis in patients admitted to Stanford Hospital with a systemic infection and positive blood cultures, as this may improve the clinical care of this population of patients.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    Some patients admitted to the hospital have blood-borne infections. Occasionally, these blood infections can end up inside the eye and cause an infection inside the eye (called endogenous endophthalmitis).

    Prior to modern and rapid treatment of systemic infections, the rate of endogenous endophthalmitis was reported to be 37% in 1982. By 1997, the rate was reported to be 2.8%. This study aims to determine the rate of endogenous endophthalmitis at Stanford Hospital in the modern medical era in that our rates may be different as those reported in the literature. This potential difference may be a reflection of treatment protocols and antibiotics currently in use at Stanford Hospital.

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    145 participants
    Observational Model:
    Cohort
    Time Perspective:
    Prospective
    Official Title:
    Endogenous Endophthalmitis Rates, Clinical Course, and Outcomes
    Study Start Date :
    Jul 1, 2010
    Actual Primary Completion Date :
    Jun 1, 2013
    Actual Study Completion Date :
    Jun 1, 2013

    Outcome Measures

    Primary Outcome Measures

    1. Positive intraocular infection [1 day]

    Secondary Outcome Measures

    1. Visual acuity [2 wk]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    N/A and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No

    Inclusion Criteria:All patients admitted to Stanford Hospital that have a systemic blood-borne infection and on which an Ophthalmology consult to rule out endogenous endophthalmitis is performed will be included in the study. Exclusion Criteria:None

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Stanford University School of Medicine Stanford California United States 94305

    Sponsors and Collaborators

    • Stanford University

    Investigators

    • Principal Investigator: Theodore Leng, Stanford University

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Theodore Leng, Clinical Assistant Professor of Ophthalmology, Stanford University
    ClinicalTrials.gov Identifier:
    NCT01323868
    Other Study ID Numbers:
    • SU-03232011-7621
    • IRB-18785
    First Posted:
    Mar 28, 2011
    Last Update Posted:
    Nov 18, 2014
    Last Verified:
    Nov 1, 2014
    Additional relevant MeSH terms:
    Endophthalmitis

    Study Results

    No Results Posted as of Nov 18, 2014