Use of Arimidex and Zoladex as Pretreatment to IVF in Women With Ovarian Endometriosis
Sponsor
Rigshospitalet, Denmark (Other)
Overall Status
Completed
CT.gov ID
NCT00286351
Collaborator
(none)
20
1
Study Details
Study Description
Brief Summary
Does a combination of Arimidex and Zoladex make endometriomas shrink and how is the following IVF outcome
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Phase 4 |
Study Design
Study Type:
Interventional
Allocation:
Non-Randomized
Intervention Model:
Single Group Assignment
Masking:
None (Open Label)
Primary Purpose:
Treatment
Study Start Date
:
Jan 1, 2005
Outcome Measures
Primary Outcome Measures
- size of endometriomas after 2½ month of combined downregulation []
Eligibility Criteria
Criteria
Ages Eligible for Study:
20 Years
to 40 Years
Sexes Eligible for Study:
Female
Accepts Healthy Volunteers:
No
Inclusion Criteria:
-
Endometrioma(s)with a size of 20-70 mm, persisted for at least 3 cycles
-
Couples with indication and wish for IVF/ICSI
-
Age of women: 20-40 years
-
Regular menstrual cycle within normal range (21-35 days)
-
Body Mass Index (BMI): 18-30 kg/m2
Exclusion Criteria:
-
History with osteoporosis, liver-, kidney- or heart disease or thromboembolic disease
-
Treatment of endometriosis with GnRH agonist during the last 3 month
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | The Fertility Clinic, Copenhagen University Hospital, Rigshospitalet | Copenhagen | Copenhagen East | Denmark | 2100 |
Sponsors and Collaborators
- Rigshospitalet, Denmark
Investigators
- Principal Investigator: Kristine Lossl, medical doctor, The Fertility Clinic, Copenhagen University Hospital Rigshospitalet
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
,
,
ClinicalTrials.gov Identifier:
NCT00286351
Other Study ID Numbers:
- endo 220604
First Posted:
Feb 3, 2006
Last Update Posted:
Apr 23, 2007
Last Verified:
Apr 1, 2007