Endoplasmic Reticulum Stress in Chronic Respiratory Diseases
Sponsor
Chonbuk National University (Other)
Overall Status
Unknown status
CT.gov ID
NCT01211015
Collaborator
(none)
50
1
Study Details
Study Description
Brief Summary
Aim: To investigate whether ER stress is implicated in the pathogenesis of various pulmonary disorders
Measurement:
-
Unfolded protein responses (UPRs) in blood (PBMCs)of patients
-
CHOP
-
GRP 78 and so on
-
Unfolded protein responses (UPRs) in blood (PBMCs)of healthy controls
-
CHOP
-
GRP 78 and so on
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
|
Study Design
Study Type:
Observational
Anticipated Enrollment
:
50 participants
Observational Model:
Case-Control
Time Perspective:
Prospective
Official Title:
Endoplasmic Reticulum (ER) Stress in Patients With Various Chronic Pulmonary Diseases
Study Start Date
:
Jul 1, 2010
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Control group healthy control group |
|
| Disease group asthma, COPD, ILD, lung malignancy |
Outcome Measures
Primary Outcome Measures
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
to 80 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
-
18 yrs
-
Definitive diagnosis as chronic pulmonary diseases by physician
Exclusion Criteria:
- Any other chronic medical illness such as DM, HTN, and other malignancy
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Chonbuk National University Hospital | Jeonju | Jeonbuk | Korea, Republic of | 561-180 |
Sponsors and Collaborators
- Chonbuk National University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
,
,
ClinicalTrials.gov Identifier:
NCT01211015
Other Study ID Numbers:
- RCPD ER stress
First Posted:
Sep 29, 2010
Last Update Posted:
Sep 29, 2010
Last Verified:
Sep 1, 2010