eFOCUS: Enhanced FoCUS in Patients With Shortness of Breath
Study Details
Study Description
Brief Summary
Retrospective observational study performed in a internal medicine ward of a French university hospital. Included patients were hospitalized for acute shortness of breath who have benefited from a eFOCUS which was defined as a focused cardiac Ultrasound with utilization of Doppler measurements.
The objectives were the therapeutic and diagnosis changes induced by eFoCUS. The primary endpoint was defined by the pooled introduction or discontinuation of diuretics, antibiotics or anticoagulants associated with eFoCUS results.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Detailed Description
It was a retrospective observational study performed in a internal medicine ward of a French University Hospital. Patients were identified in the hospital database, pertinent features and eFoCUS findings were extracted and anonymized.
Inclusion criteria:
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Adult patients admitted to an internal medicine ward from the ED for acute shortness of breath.
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Realization of an eFoCUS prescribed by the physician in charge of the patient
Exclusion criteria:
• Comprehensive echocardiography already performed Methods For each identified patient, pertinent data (demography, initial diagnosis and treatment (diuretics, antibiotics, anticoagulants)) and eFoCUS findings were extracted from the hospital files, anonymized and entered in a LibreOffice spreadsheet. Extracted diagnosis were gathered into the following categories: Community-acquired pneumonia (CAP), Acute cardiogenic pulmonary edema (ACPE), Pulmonary embolism (PE), Chronic Obstructive Pulmonary Disease (COPD) and other (OTHER).
Objectives and endpoints
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The main objective was the therapeutic change induced by eFoCUS. The primary endpoint was defined by the pooled introduction or discontinuation of diuretics, antibiotics or anticoagulants associated with eFoCUS results.
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The secondary objectives were diagnosis modifications induced by eFoCUS. Data analysis
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Numerical data were presented as mean ± SD or as median with interquartile range depending on the normality. The paired Student's t-test was used to compare normally distributed data. The chi-square test was used for the comparison of noncontinuous variables expressed as proportions. A p-value <0.05 was considered significant. All p-values were two-sided. Statistical analysis was realized with R (4.03.3) in the Rstudio® environment.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Patients Patients hospitalized for shortness of breath with realization of an enhanced FoCUS |
Diagnostic Test: Diagnostic test
Cardiac Ultrasound in order to explore the causes of shortness of breath
Other Names:
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Outcome Measures
Primary Outcome Measures
- Pooled introduction or discontinuation of diuretics, antibiotics or anticoagulants [up to 24 hours after eFoCUS]
Number of patients for whom there was an introduction or discontinuation of diuretics, antibiotics or anticoagulants associated with Focused cardiac ultrasound
Secondary Outcome Measures
- Changes of diagnostic categories associated with eFOCUS [up to 24 hours after eFoCUS]
Number of patients for whom the diagnostic category (pneumonia, acute cardiac failure, pulmonary embolism, COPD, other) was modified after Focused cardiac ultrasound
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Adult patients admitted to a internal medicine ward from the ED for acute shortness of breath.
-
Realization of an eFoCUS prescribed by the physician in charge of the patient
Exclusion Criteria:
- Comprehensive echocardiography already performed
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Nantes University Hospital | Nantes | France | 44093 |
Sponsors and Collaborators
- Nantes University Hospital
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- eFOCUS 1