eGFR: Estimated Glomerular Filtration Rate After Kidney Transplantation - the Formula MDRD, CKD-EPI or Cockroft-Gault?

Sponsor

Medical University of Warsaw (Other)

Overall Status

Completed

CT.gov ID

NCT02443363

Collaborator

(none)

170

Enrollment

Location

Duration (Months)

33.8

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The study included 300 patients who are post-kidney transplantation (> 3 months and <10 years). An analysis of body composition using bioelectrical impedance, calculated BMI and serum creatinine was determined. Glomerular filtration rate (GFR) was calculated using the formula CKD-EPI, Modification of Diet in Renal Disease (MDRD) and Cockroft-Gault.

Condition or Disease	Intervention/Treatment	Phase
Renal Function Disorder	Other: Estimating of formula MDRD, CKD-EPI, Cockroft-Gault, Device: Tanita BC 418- Bioelectrical impedance analysis

Study Design

Study Type:

Observational

Actual Enrollment :

170 participants

Observational Model:

Cohort

Time Perspective:

Cross-Sectional

Official Title:

Estimated Glomerular Filtration Rate After Kidney Transplantation - the Formula Modification of Diet in Renal Disease (MDRD), Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) or Cockroft-Gault?

Study Start Date :

Apr 1, 2015

Actual Primary Completion Date :

Sep 1, 2015

Actual Study Completion Date :

Sep 1, 2015

Arms and Interventions

Arm	Intervention/Treatment
Patients After Kidney Transplantation A total of 300 consecutive patients admitted to routine visit in Transplant Centre with functioning graft longer than 3 months to 10 years	Other: Estimating of formula MDRD, CKD-EPI, Cockroft-Gault, Device: Tanita BC 418- Bioelectrical impedance analysis The device measured the size of total body water (TBW), fat mass (FM%), visceral fat%, fat free mass (FFM), and basal metabolic rate (BMR) (kcal).

Arm

Intervention/Treatment

Patients After Kidney Transplantation

A total of 300 consecutive patients admitted to routine visit in Transplant Centre with functioning graft longer than 3 months to 10 years

Other: Estimating of formula MDRD, CKD-EPI, Cockroft-Gault,

Device: Tanita BC 418- Bioelectrical impedance analysis

The device measured the size of total body water (TBW), fat mass (FM%), visceral fat%, fat free mass (FFM), and basal metabolic rate (BMR) (kcal).

Outcome Measures

Primary Outcome Measures

Differences in estimating GFR using formula MDRD, CKD-EPI and Cockroft-Gault in short and long-term postoperative period. [1 day]

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

give voluntary consent to participate in the study
functioning graft longer than 3 months to 10 years
no clinical cardiovascular disease during the 6 months preceding entry
stable graft function- glomerular filtration rate > 30 ml/min/1.73 m2, creatinine concentration <2.5 mg/dl

Exclusion Criteria:

not meet the above criteria
episode of illness (for example: infection)
pregnancy

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Medical University of Warsaw	Warsaw	Mazovian	Poland	02-091

Sponsors and Collaborators

Medical University of Warsaw

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Łukasz Czyżewski, Łukasz Czyżewski, Medical University of Warsaw

ClinicalTrials.gov Identifier:

NCT02443363

Other Study ID Numbers:

GFR/KTx/2015/04

First Posted:

May 13, 2015

Last Update Posted:

Oct 2, 2015

Last Verified:

Sep 1, 2015

Study Results

No Results Posted as of Oct 2, 2015