Etiology of Anemia Among Preschool Children in Ethiopia

Sponsor
Oklahoma State University (Other)
Overall Status
Completed
CT.gov ID
NCT05626647
Collaborator
Ethiopian Public Health Institute (Other), Addis Ababa University (Other)
590
1
10.1
58.5

Study Details

Study Description

Brief Summary

This study aims to determine the etiology of anemia among preschool children in selected regions of Ethiopia. The study is a longitudinal observational study to assess the determinant factors of anemia in two different seasons.

The main questions it aims to answer are:
  1. What is the prevalence and etiology of anemia in the two different (Post and Pre-harvest) seasons?

  2. What is the strength of the interaction between anemia and each of the determinant factors being considered?

The participant's dietary intake and anthropometric measurement have been assessed, and biological samples (Blood and Stool) were collected to determine the prevalence of anemia and the factors contributing to it.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    Background: Although the country made a significant change in the burden of malnutrition in all its forms in the past two decades, the issue remains unacceptably high across all regions of Ethiopia. The national prevalence of anemia among children 6-59 months was very high 57% and one of the public health concerns in 2016. Although the country is known as a data-rich country, in some specific indicators, there is a lack of data and evidence to alleviate the nutritional gaps through an informed decision-making process. In this particular case, there is a lack of evidence relating to child anemia in Ethiopia, especially since there is no comprehensive information about the determinant factors of anemia.

    Objective: The objective of the current survey is to determine the etiology of anemia and its public health implications among under-five children in selected ecological zones of Ethiopia at different seasons.

    Method: This survey will be a community-based, longitudinal panel study and will be conducted in two different (post-harvest and pre-harvest) seasons in the 2014 Ethiopian calendar year. A nationally representative sample was calculated and allocated to three purposely selected regions (Amhara, Southern Nation, Nationalities, and Peoples' Region (SNNPR), and Somali) in consideration of three different ecological zones (lowlands, midlands, and highlands). The study population will be children aged 6 - 59 months with caregivers/mothers with a sample size of 1212 under-five children from 1212 households. The indicators collected for the survey are dietary intake, anthropometric measurement, and biological samples (Blood and Stool).

    Expected benefit: The findings of this survey will provide information on the etiology of anemia that will inform short-term policy decisions, especially for case-specific nutrition-sensitive interventions, and that will contribute to long-term policy decisions for comprehensive nutrition intervention programs.

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    590 participants
    Observational Model:
    Ecologic or Community
    Time Perspective:
    Other
    Official Title:
    Etiology of Anemia Among Preschool Children and Its Public Health Implication in Selected Regions of Ethiopia: A Community-Based Longitudinal Study
    Actual Study Start Date :
    Nov 1, 2021
    Actual Primary Completion Date :
    Mar 4, 2022
    Actual Study Completion Date :
    Sep 4, 2022

    Outcome Measures

    Primary Outcome Measures

    1. Prevalence of anemia among preschool children in selected regions of Ethiopia in the two different (Post and Pre harvest) seasons? [From November 2021 to September 2022]

      Blood hemoglobin level below 11mg/dL

    Secondary Outcome Measures

    1. Factors contributing to anemia anemia among preschool children in selected regions of Ethiopia in the two different (Post and Pre harvest) seasons? [From November 2021 to September 2022]

      Micronutrient deficiency, presence of infectious disease, and genetic problems contributing to low hemoglobin concentration.

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    6 Months to 59 Months
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:
    • Children 6-53 months during the baseline survey and who have stayed more than 6 months in the selected household of the Amhara or SNNPR or Somali regions of Ethiopia and have no plan to move from the study area during the study period
    Exclusion Criteria:
    • Children older than the youngest child between 6-53 months of age (If more than one eligible child is in the Household) during the baseline survey.

    • Children with severe illness

    • Guests

    • If participants lose their willingness to participate in this study

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Ethiopian Public Health Institute Addis Ababa Ethiopia

    Sponsors and Collaborators

    • Oklahoma State University
    • Ethiopian Public Health Institute
    • Addis Ababa University

    Investigators

    • Study Chair: Barbara J Stocker, Prof, Oklahoma State University

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Solomon Hailu, Principal Investigator, Oklahoma State University
    ClinicalTrials.gov Identifier:
    NCT05626647
    Other Study ID Numbers:
    • IRB-21-505
    First Posted:
    Nov 25, 2022
    Last Update Posted:
    Nov 29, 2022
    Last Verified:
    Nov 1, 2022
    Individual Participant Data (IPD) Sharing Statement:
    Undecided
    Plan to Share IPD:
    Undecided
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Keywords provided by Solomon Hailu, Principal Investigator, Oklahoma State University
    Additional relevant MeSH terms:

    Study Results

    No Results Posted as of Nov 29, 2022