Etiology Of Recurrent Varicose Veins After Stripping Or Ablation Of Superficial Venous System

Sponsor
Assiut University (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05693350
Collaborator
(none)
50
22.1

Study Details

Study Description

Brief Summary

Number of patients and causes and patterns of recurrent varicose veins in the lower limbs in patients with history of varicose veins stripping or ablation of the superficial venous system.

Condition or Disease Intervention/Treatment Phase
  • Diagnostic Test: DUS

Detailed Description

Recurrence of varicose veins following surgery is a common, complex and costly problem in vascular surgery. Despite improvements in preoperative evaluation and methods of treatment, recurrence following varicose vein surgery is reported to occur in between 20 and 80% of cases. Many theories have been put forward concerning the underlying mechanisms and causes. These include poor understanding of the venous anatomy and haemodynamics, inadequate preoperative assessment, inappropriate or incomplete surgery and development of new sites of venous reflux as a consequence of disease progression or neovascularisation. However, it is difficult to evaluate these suggestions since the studies from which they arise vary greatly in their definitions of recurrence, preoperative assessment, initial treatment, classification and method and duration of follow-up.

Study Design

Study Type:
Observational
Anticipated Enrollment :
50 participants
Observational Model:
Cohort
Time Perspective:
Prospective
Official Title:
Etiology Of Recurrent Varicose Veins After Stripping Or Ablation Of Superficial
Anticipated Study Start Date :
Mar 1, 2023
Anticipated Primary Completion Date :
Oct 1, 2024
Anticipated Study Completion Date :
Jan 1, 2025

Outcome Measures

Primary Outcome Measures

  1. Etiology of recurrence of varicose veins in patients previously treated by stripping and ligation or endovenous ablation. [Five years]

    Track the recurrence of varicose veins after intervention

Secondary Outcome Measures

  1. Quality of life was assessed by the Aberdeen Varicose Vein Questionnaire (AVVQ) [Five years]

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 60 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
    1. Ages eligible for the study: 18-60. 2) Sexes eligible for the study: All. 3) Patients with previous intervention for varicose veins. 4) Patients with primary or secondary varicosities. 5) Patient's compliance to follow-up.
Exclusion Criteria:
  1. Patients with no history of interventions for varicose veins. 2) Patients treated with injection sclerotherapy alone. 3) Pregnant women. 4) Patients with arterial disease in the same limb (ABI <0.8). 5) Patients with post-thrombotic syndrome

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • Assiut University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

Responsible Party:
Mohamed Tarek Mostafa, Resident Doctor, Assiut University
ClinicalTrials.gov Identifier:
NCT05693350
Other Study ID Numbers:
  • Recurrent Varicose Veins
First Posted:
Jan 23, 2023
Last Update Posted:
Jan 23, 2023
Last Verified:
Jan 1, 2023
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of Jan 23, 2023