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Evaluating the Fluid Balance of Mechanically Ventilated Patients by Ultrasonography

Sponsor
Jagiellonian University (Other)
Overall Status
Completed
CT.gov ID
NCT03204292
Collaborator
(none)
57
Enrollment
1
Location
18.1
Duration (Months)
3.2
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

ratio of the diameter of inferior vena cava to the diameter of the thoracic aorta (IVC / Ao) depends on the daily balance of fluids.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    During the routine abdominal ultrasound, the basilar and abdominal aorta were measured using a Sparq Philips ultrasonograph with a convex probe set in abdominal mode. All measurements were performed in one patient by the same operator who were experienced and performed the appropriate course of ultrasonography. The IVC and abdominal aorta were visualized using a paramedian long-axis view via a subcostal approach according to the methodology described by the American Society of Echocardiography. Inferior vena cava width was assessed at an interval of approximately 1 cm distal from connection of the hepatic vein to the inferior vena cava. No significant changes were observed in the width of the inferior vena cava during various respiratory phases, because of the positive pressure ventilation. The widest value was always chosen for the data. The assessment of the width of the abdominal aorta was performed above arise of the celiac trunk, at the height of the vein of the lower vena cava. The width of the inferior vena cava and the abdominal aorta was assessed using transthoracic ultrasound for the following five days. Daily differences in the amount of fluid intake and lost was recorded. CVP measurement was performed.

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    57 participants
    Observational Model:
    Other
    Time Perspective:
    Prospective
    Official Title:
    Measurement of the Inferior Vena Cava as a Method of Evaluating the Fluid Balance of Mechanically Ventilated Patients
    Study Start Date :
    Jul 1, 2015
    Actual Primary Completion Date :
    Jan 1, 2017
    Actual Study Completion Date :
    Jan 1, 2017

    Arms and Interventions

    Arm Intervention/Treatment
    IVC/Ao

    ultrasound, the inferior vena cava and abdominal aorta were measured. Inferior vena cava width was assessed at an interval of approximately 1 cm distal from connection of the hepatic vein to the inferior vena cava. No significant changes were observed in the width of the inferior vena cava during various respiratory phases, because of the positive pressure ventilation. The widest value was always chosen for the data. The assessment of the width of the abdominal aorta was performed above arise of the celiac trunk, at the height of the vein of the lower vena cava.

    Outcome Measures

    Primary Outcome Measures

    1. fluid balance [1 day]

      the width of the vena cava and abdominal aorta was measured every day morning. The difference in in taken and excreted fluids

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years to 100 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:

    • patients who were hospitalized in the Intensive Care Unit

    • severe respiratory failure requiring mechanical ventilation

    Exclusion Criteria:

    • spontaneous breathing,

    • severe vascular disease,

    • increased intra-abdominal pressure,

    • cardiac pacemaker

    • cardioverter defibrillator

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 University Hospital Cracow Małopolskie Poland 31-501

    Sponsors and Collaborators

    • Jagiellonian University

    Investigators

    • Principal Investigator: Tomasz Skladzien, Ph.D., Jagiellonian University

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Tomasz Skladzien, senior assistant, Jagiellonian University
    ClinicalTrials.gov Identifier:
    NCT03204292
    Other Study ID Numbers:
    • 122.6120.85.2015
    First Posted:
    Jul 2, 2017
    Last Update Posted:
    Jul 2, 2017
    Last Verified:
    Jun 1, 2017
    Individual Participant Data (IPD) Sharing Statement:
    No
    Plan to Share IPD:
    No
    Keywords provided by Tomasz Skladzien, senior assistant, Jagiellonian University
    Inferior vena cava
    Fluid responsiveness
    Central venous pressure

    Study Results

    No Results Posted as of Jul 2, 2017