DOP-RENAL: Study of the Evolution Profile of the Renal Doppler in the Perioperative Hepathic Transplantation

Sponsor

University Hospital, Strasbourg, France (Other)

Overall Status

Recruiting

CT.gov ID

NCT04682236

Collaborator

(none)

Enrollment

Location

17.9

Anticipated Duration (Months)

1.7

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Liver transplantation is associated with a modification of the perfusion pressures of the abdominal organs (preoperative portal hypertension in connection with liver pathology, and normalization of the perfusion pressures during surgery). This abrupt change in the infusion regime is probably responsible for an alteration in renal function in some patients, and the identification of renal vascular profiles using Doppler could point to pathological profiles, which should be diagnosed early.

Condition or Disease	Intervention/Treatment	Phase
Acute Renal Failure

Study Design

Study Type:

Observational

Anticipated Enrollment :

30 participants

Observational Model:

Case-Control

Time Perspective:

Retrospective

Official Title:

Study of the Evolution Profile of the Renal Doppler in the Perioperative Hepathic Transplantation - Interest in Predicting the Occurence of Acute Postoperative Renal Faillure

Actual Study Start Date :

Nov 25, 2020

Anticipated Primary Completion Date :

May 25, 2022

Anticipated Study Completion Date :

May 25, 2022

Outcome Measures

Primary Outcome Measures

Retrospective analysis of the development profiles of renal dopplers in perioperative liver transplantation [Files analysed retrospectily from July 1st, 2019 to June 30, 2020 will be examined]

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

Patient of full age (≥18 years)
Patient operated on at the HUS for a liver transplant, between July 1, 2019 and June 30, 2020.
Patients having undergone an evaluation of hepatic and renal vascular profiles perioperatively.
Patients hospitalized in the surgical intensive care unit after hepatic transplant surgery.
Patient not having expressed, after information, the reuse of his data for the purposes of this research

Exclusion Criteria:

Patient who expressed his opposition to participating in the study
Patient with suspected obstructive acute renal failure
Stenosis of renal arteries known at the time
End-stage renal disease on dialysis
Impossibility of giving the subject informed information (difficulties in understanding the subject, etc.)
Subject under safeguard of justice