Examination of Sleep and Family Functioning in Pediatric Craniopharyngioma Patients

Sponsor

St. Jude Children's Research Hospital (Other)

Overall Status

Completed

CT.gov ID

NCT03330080

Collaborator

Virginia Commonwealth University (Other)

Enrollment

Location

11.5

Actual Duration (Months)

3.6

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Pediatric craniopharyngioma patients experience significant endocrine and sleep dysregulation difficulties. Sleep is a crucial part of children's healthy development, and sleep difficulties are associated with severe functional morbidity. Insufficient sleep, excessive daytime sleepiness, and poor sleep quality have all been significantly related to academic, behavioral, and emotional functioning in children and adolescents. Ecological momentary assessments (EMA) will be used to collect observational data.

EMA data will be collected twice daily for one week. For the morning EMA administration, participants will be asked about their sleep. During the evening administration, participants will be asked about their daytime sleepiness, overall well-being, and family functioning. Covariates also administered during the evening administration include medication administration (Y/N) and total screen time. At the end of the EMA data collection period (on day 7 OR 8), participants will be sent a survey asking them to report - anonymously - their overall experience and satisfaction with the EMA data collection method.

Condition or Disease	Intervention/Treatment	Phase
Craniopharyngioma

Detailed Description

After recruitment and informed consent/assent is obtained for the current study, participants will be asked to complete a questionnaire battery online (via REDCap) assessing sleep habits, daytime sleepiness, family routines, family functioning, and overall quality of life in the past six months. The relationship between subjective sleep ratings obtained from the parent craniopharyngioma study at St. Jude (RT2CR) at diagnosis and 3 months later (T1 and T2) and family functioning/routines at the follow-up study (T3) will be assessed. The researchers have permission to use data for all participants who consent to participate in this follow-up EMA study.

Children will be sent electronic surveys two times per day (i.e., morning and evening) for seven days using Ilumivu software (https://ilumivu.com/mema-demo). Ilumivu is an established EMA tool that offers an in-mobile app for participants to respond to questionnaires in real time with limited burden. This application will send notifications to participants to remind them to complete surveys and record response times for each survey.

Study Design

Study Type:

Observational

Actual Enrollment :

41 participants

Observational Model:

Cohort

Time Perspective:

Prospective

Official Title:

Examining Sleep and Family Functioning in Pediatric Craniopharyngioma Using Ecological Momentary Assessment

Actual Study Start Date :

Feb 12, 2018

Actual Primary Completion Date :

Jan 29, 2019

Actual Study Completion Date :

Jan 29, 2019

Arms and Interventions

Arm	Intervention/Treatment
Ecological momentary assessment (EMA) The ecological momentary assessment (EMA) will be used for participants to complete surveys from home on two occasions each day over seven days.

Outcome Measures

Primary Outcome Measures

Rate of participation [Once at enrollment]
Study feasibility will be assessed by calculating the participation rate as follows: the number of participants who agree to participants divided by the number who are approached to participate.

Eligibility Criteria

Criteria

Ages Eligible for Study:

8 Years to 18 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

Craniopharyngioma diagnosis
Access to smartphone or a tablet
Agreement to download Ilumivu application
The ability for the participant to answer questionnaires (i.e., no cognitive or developmental diagnoses that would preclude understanding and completing child self-report questionnaires)
Age between 8 and 18 years old at the time of enrollment onto St. Jude protocol RT2CR.
Participated in sleep study component of RT2CR

Exclusion Criteria:

Limited English proficiency as evidenced by an inability to read and respond to EMA survey questions
Visual or sensorimotor impairment (e.g., loss of sight)