Executive Functions and Preterm Children in 11 to 12 Year Old
Study Details
Study Description
Brief Summary
Preterm children have a high risk for neurodevelopmental impairments. The impact on motor functions and neurosensory functions is demonstrated but the incidence of executive functions is not described for preterm infants.
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Detailed Description
It is an epidemiologic, observational, prospective study. All patients, included in the LIFT cohort, in 11 to 12 year old during the period study, are contacted by mail. Patients with congenital anomalies or genetic syndromes are excluded. Children with parents who do not speak French are excluded. Antenatal and postnatal criteria known to be associated with disorders of executive functions are collected as gestational age, sex, multiple pregnancy, intrauterine growth retardation, antenatal or postnatal steroid use, breastfeeding, cerebral injuries and socio-economic status. After a couple of weeks, parents are contacted by a study manager, by phone call, to collect parental consent and answer some parental questions. After consent collect, BRIEF questionnaires are sending. If they wish, parents could give the BRIEF teacher questionnaire to the mean teacher. Teachers send by themselves their response. An informatic version is available with a personal link given especially by mail for each child. All data are anonymous. BRIEF questionnaire is composed of 86 items, exploring 2 main domains: behavior and metacognition. Twenty minutes are necessary to complete questionnaire. In case of no questionnaire return after one month, parents are contacted by phone. The investigators hypothesize a lost to follow-up at 0.25 and no response at 0.35. The response expected is 300 questionnaires.
Study Design
Outcome Measures
Primary Outcome Measures
- Incidence of disorders of executive functions in 11 to 12 year old in former preterm of gestational age less than 34 weeks, from the Behavioral Rating Inventory of Executive Function questionnaire. [11 to 12 years after preterm birth.]
The sum of the 86 items is calculated.
Secondary Outcome Measures
- Find neonatal factors associated with executive functions disorders in former prematures in 11 to 12 year old [11 to 12 years after preterm birth]
estimate adequacy between BRIEF questionnaire performed/completed by parents and BRIEF questionnaire performed by teacher.
Eligibility Criteria
Criteria
Inclusion Criteria:
- patient in 11 to 12 year old, included in LIFT cohort
Exclusion Criteria:
- Congenital abnormalities including nervous system malformations; genetic diseases; incomplete understanding of written and oral French by parents
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | CHU Nantes | Nantes | France | 44000 |
Sponsors and Collaborators
- Nantes University Hospital
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- RC18_0201