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ETAT PSA: Executive Training and Anomia Therapy in Chronic Post-stroke Aphasia

Sponsor
University Hospital, Montpellier (Other)
Overall Status
Completed
CT.gov ID
NCT05101408
Collaborator
(none)
10
Enrollment
1
Location
3.9
Actual Duration (Months)
2.5
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Aphasia is a devastating acquired language impairment mainly caused by stroke, in which anomia is a quintessential clinical feature. If speech-language therapy (SLT) has been shown to be effective for persons with aphasia, the relative efficiency of one SLT strategy over another remains a matter of debate. The influential relationship between language, executive functions and aphasia rehabilitation outcomes has been addressed in a number of studies, but only few of them have studied the effect of adding an executive training to linguistic therapies.The aim of this study is to measure the efficiency of a protocol combining anomia therapy and executive training on naming skills and discourse in post-stroke aphasic persons at the chronic stage

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    10 participants
    Observational Model:
    Cohort
    Time Perspective:
    Prospective
    Official Title:
    Combining Executive Training and Anomia Therapy in Chronic Post-stroke Aphasia : a Single Case Experimental Design -SCED Preliminary Study
    Actual Study Start Date :
    Sep 1, 2021
    Actual Primary Completion Date :
    Dec 1, 2021
    Actual Study Completion Date :
    Dec 30, 2021

    Outcome Measures

    Primary Outcome Measures

    1. Evolution of individual naming scores [2 days]

      Evolution of individual naming scores during baseline and treatment phases Participants are asked to name pictures from a personal naming task constituted of 100 black and white pictures and scores are expressed as percent of correct responses (min 0, max 100): higher percents meaning a better outcome. A visual analysis of the evolution of these scores along the course of the treatment will be conducted.

    2. Comparison of discourse [2 days]

      Comparison of discourse scores before and after the treatment For each participant, four different samples of discourse are elicited before and after the treatment (picture description, personal narrative, book supported narrative, procedural information). The mean number of correct words per minute is then computed for each participant, and compared between the two time points, higher scores meaning a better outcome.

    Secondary Outcome Measures

    1. Comparison of executive scores [2 days]

      Comparison of executive scores before and after the treatment Executive scores are computed before and after treatment for each participant, from the Modified Card Sorting Test (Nelson, 1976), in which higher number of categories achieved means a better outcome, and from a verbal fluency task in which higher number of words produced in 2 minutes means a better outcome

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years to 80 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion criteria:

    • 18 < age > 80 years

    • adult person with chronic post-stroke aphasia (> 6 months postonset)

    • receiving SLT rehabilitation 3 times a Week

    Exclusion criteria:

    • presence of apraxia of speech

    • major impairment of comprehension

    • history of other neurological or psychiatric disease

    Exclusion criteria:

    • presence of apraxia of speech

    • presence of major impairment of comprehension

    • presence of history of other neurological or psychiatric disease

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Uhmontpellier Montpellier France 34295

    Sponsors and Collaborators

    • University Hospital, Montpellier

    Investigators

    • Principal Investigator: Sylvie Moritz-Gasser, University Hospital, Montpellier

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    University Hospital, Montpellier
    ClinicalTrials.gov Identifier:
    NCT05101408
    Other Study ID Numbers:
    • RECHMPL21_0597
    First Posted:
    Nov 1, 2021
    Last Update Posted:
    Apr 12, 2022
    Last Verified:
    Apr 1, 2022
    Individual Participant Data (IPD) Sharing Statement:
    Undecided
    Plan to Share IPD:
    Undecided
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Keywords provided by University Hospital, Montpellier
    Aphasia
    Speech-Language Therapy
    Anomia
    Executive functions
    Additional relevant MeSH terms:
    Stroke
    Aphasia
    Anomia

    Study Results

    No Results Posted as of Apr 12, 2022