Autonomical and Hemodynamic Repercussions on Excentric Resistance in Different Intensities With Blood Flow Restriction
Study Details
Study Description
Brief Summary
Introduction: Studies on resistance training (RT) associated with blood flow restriction (BFR) have emerged as an alternative method of gaining strength and hypertrophy; however, the cardiovascular and autonomic repercussion of BFR at different intensities is unknown. Thus, it becomes relevant to investigate this type of training in post-exercise. Objective: investigate and compare autonomic and hemodynamic responses of acute eccentric RT with different intensities associated or not to BFR in healthy youngsters. Method: This is a randomized clinical trial including 60 healthy men aged 18-35 years, divided into four groups according to exercise intensity and BFR: 80% without BFR, 40% without BFR, 80% with BFR and 40% with BFR. Exercise intensity will be determined by the peak of excentric torque on the dinamometer isokinetic method and by the BFR, as being 40% of the intensity required for the complete examination of the blood flow evaluated by Doppler. Participants will do an eccentric femoral quadriceps muscle exercise session on the isokinetic dynamometer according to the previously randomized group. For recovery analyzes, the recovery heart rate (HRR) in the 1st (HRR1) and 2nd (HRR2) minute, rMSSD of 30 seconds, the hemodynamic parameters (heart rate, systolic and diastolic blood pressure, respiratory rate, peripheral oxygen saturation and rate pressure product) and heart rate variability (HRV) indices analyzed in the time domain (mean HR, rMSSD and SDNN), frequency domain (LF and HF [nu and ms2]) and Poincaré plot (SD1 and SD2). The analysis will be occur on baseline, immediately e after the excentric exercise and in the post exercise period for 60 minutes. Descriptive statistics method and comparison of HRV indices and hemodynamic parameters between moments and groups will be performed with the aid of the analysis of variance technique for the repetitive measures model without the schema of two sets of tests to follow . The level of significance will be p <0.05.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: High intensity eccentric training high intensity (80% isometric peak) eccentric training of the knee extensors in the isokinetic will be performed during 6 weeks, 3 times a week. |
Other: eccentric exercise with blood flow restriction
High/low intensity eccentric training group (80% and 40% of isometric peak torque) with or not blood flow restriction.
|
| Experimental: High intensity eccentric training with blood flow restriction high intensity (80% isometric peak) eccentric training of the knee extensors in the isokinetic associated with a pressure cuff placed in the proximal thigh (40% of absolute occlusion pressure) will be performed during 6 weeks, 3 times a week. |
Other: eccentric exercise with blood flow restriction
High/low intensity eccentric training group (80% and 40% of isometric peak torque) with or not blood flow restriction.
|
| Experimental: Low intensity eccentric training A low intensity (40% isometric peak) eccentric training of the knee extensors in the isokinetic will be performed during 6 weeks, 3 times a week. |
Other: eccentric exercise with blood flow restriction
High/low intensity eccentric training group (80% and 40% of isometric peak torque) with or not blood flow restriction.
|
| Experimental: Low intensity eccentric training with blood flow restriction A low intensity (40% isometric peak) eccentric training of the knee extensors in the isokinetic associated with a pressure cuff placed in the proximal thigh (40% of absolute occlusion pressure)will be performed during 6 weeks, 3 times a week. |
Other: eccentric exercise with blood flow restriction
High/low intensity eccentric training group (80% and 40% of isometric peak torque) with or not blood flow restriction.
|
Outcome Measures
Primary Outcome Measures
- heart rate variability indices in the time domain [Change from baseline at 3rd week and 6rd week]
mean HR, rMSSD and SDNN in ms
- heart rate variability indices analyzed in the Poincaré plot [Change from baseline at 3rd week and 6rd week]
SD1 and SD2 in ms
- heart rate variability indices in the frequency domain [Change from baseline at 3rd week and 6rd week]
LF and HF in nu and ms2
- vagal reentry [Change from 1 day at 10 day and 18 day]
rMSSD of 30 seconds in ms
- heart rate recovery [Change from 1 day at 10 day and 18 day]
the recovery heart rate (HRR) in the 1st (HRR1) and 2st (HRR2) minute [bpm]
Secondary Outcome Measures
- hemodynamic parameter [through study completion, an average of 6 weeks]
heart rate [bpm]
- hemodynamic parameter [through study completion, an average of 6 weeks]
systolic and diastolic blood pressure [mmHg]
- hemodynamic parameter [through study completion, an average of 6 weeks]
respiratory rate [irpm]
- hemodynamic parameter [through study completion, an average of 6 weeks]
peripheral oxygen saturation [%]
Eligibility Criteria
Criteria
Inclusion Criteria:
-
male sex;
-
healthy;
-
aged between 18 and 35 years
Exclusion Criteria:
-
smokers;
-
alcoholics;
-
use drugs that influenced cardiac autonomic activity;
-
cardiovascular, metabolic or endocrine diseases.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Leonardo Kesrouani Lemos | Presidente Prudente | SP | Brazil | 19050-050 |
Sponsors and Collaborators
- Paulista University
Investigators
- Principal Investigator: Franciele M Vanderlei, PhD, Paulista State University
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- U1111-1232-0808