SpatioCog: Exploration of the Role of Vision on Spatial Cognition
Sponsor
Hospices Civils de Lyon (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT06088797
Collaborator
(none)
100
26
Study Details
Study Description
Brief Summary
Atypical developpement of spatial cognition has been shown in congenital bindness with some consequences on mathematic learning (Cattaneo et al., 2010) as well as on the mental representation of spatial maps (Thinus-Blanc & Gaunet, 1997). This raises the issue of the role of vision in spatial abilities underlying mathematics and locomotion. These difficulties could also be found in case of partial visual deficiency, like very low visual acuity or large peripheral shrinkage of the visual field.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Study Type:
Observational
Anticipated Enrollment
:
100 participants
Observational Model:
Case-Control
Time Perspective:
Prospective
Official Title:
Exploration of the Role of Vision on Spatial Cognition
Anticipated Study Start Date
:
Nov 1, 2023
Anticipated Primary Completion Date
:
Jan 1, 2026
Anticipated Study Completion Date
:
Jan 1, 2026
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| healthy subjects First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes |
Other: METRIC COMPARISON Tasks : Tactile PVSE test
Tactile PVSE test The tests are presented in 6 independent booklets, each of which tests a distinct skill: comparison of lengths, comparison of sizes, comparison of obliques, perception of environments, comparison of relative positions in relation to a frame and comparison of relative positions with distractors.
The assessment sheet presented in a table with the expected answers will allow you to note whether the answers are correct (rating 1) or not (rating 0). A total of the correct answers from all the sub-tests will give a total score.
Other: METRIC COMPARISON Tasks : Classic PVSE test
Classic PVSE test Use of the standardized PVSE test printed on thick white paper in 6 separate booklets each containing a subtest (length, size, oblique, middle, relative position and relative position with distractor)
The assessment sheet presented in a table with the expected answers will allow you to note whether the answers are correct (rating 1) or not (rating 0). A total of the correct answers from all the sub-tests will give a total score.
Other: Mental imagery task
This involves answering questions concerning the position or identity of 2 or 3 objects on the basis of the mental representation of a grid by auditory guidance. Each grid must be constructed mentally with the verbal description of the path and the objects encountered.
Other: Proprioceptive spatial representation tasks
16 configurations of 3 objects with direct or indirect passive exploration of their relative positions.
Each grid is presented 3 times with the following 3 questions to which the subject answers yes or no by forced choice
a single measure of the number of correct answers which will be the sum of the correct answers obtained to each of the 3 questions in the direct vs indirect condition
Other: Tasks assessing number sense based on relative positions or lengths
Pointing exercises on a digital line of 50 cm paper tape: the participant points with his finger to a position on the tape, according to the verbal request of the experimenter
Measures the intermanual gap during requests for evaluation of 5 times the wand, subtracting the length of a wand, then dividing this length by 2.
Other: WISC V Similarity and Span Test
The Wechsler Intelligence Scale for Children - Fifth Edition, Australian Standard (WISC-V) is an individually administered and comprehensive clinical instrument used to assess the general thinking and reasoning skills of children aged six years to 16 years. Test results include a Full-Scale Intelligence Quotient (IQ) score as well as age-equivalent rankings and scores for Verbal Comprehension, Visual Spatial, Fluid Reasoning, Working Memory and Processing Speed composites
Other: WISC V Arithmetic subtest
The WISC-V is an individually administered, comprehensive clinical instrument for assessing the intelligence of children. The primary and secondary subtests are on a scaled score metric with a mean of 10 and a standard deviation (SD) of 3. These subtest scores range from 1 to19, with scores between 8 and 12 typically considered average.
|
| blind First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes |
Other: METRIC COMPARISON Tasks : Tactile PVSE test
Tactile PVSE test The tests are presented in 6 independent booklets, each of which tests a distinct skill: comparison of lengths, comparison of sizes, comparison of obliques, perception of environments, comparison of relative positions in relation to a frame and comparison of relative positions with distractors.
The assessment sheet presented in a table with the expected answers will allow you to note whether the answers are correct (rating 1) or not (rating 0). A total of the correct answers from all the sub-tests will give a total score.
Other: Mental imagery task
This involves answering questions concerning the position or identity of 2 or 3 objects on the basis of the mental representation of a grid by auditory guidance. Each grid must be constructed mentally with the verbal description of the path and the objects encountered.
Other: Proprioceptive spatial representation tasks
16 configurations of 3 objects with direct or indirect passive exploration of their relative positions.
Each grid is presented 3 times with the following 3 questions to which the subject answers yes or no by forced choice
a single measure of the number of correct answers which will be the sum of the correct answers obtained to each of the 3 questions in the direct vs indirect condition
Other: Tasks assessing number sense based on relative positions or lengths
Pointing exercises on a digital line of 50 cm paper tape: the participant points with his finger to a position on the tape, according to the verbal request of the experimenter
Measures the intermanual gap during requests for evaluation of 5 times the wand, subtracting the length of a wand, then dividing this length by 2.
Other: WISC V Similarity and Span Test
The Wechsler Intelligence Scale for Children - Fifth Edition, Australian Standard (WISC-V) is an individually administered and comprehensive clinical instrument used to assess the general thinking and reasoning skills of children aged six years to 16 years. Test results include a Full-Scale Intelligence Quotient (IQ) score as well as age-equivalent rankings and scores for Verbal Comprehension, Visual Spatial, Fluid Reasoning, Working Memory and Processing Speed composites
Other: WISC V Arithmetic subtest
The WISC-V is an individually administered, comprehensive clinical instrument for assessing the intelligence of children. The primary and secondary subtests are on a scaled score metric with a mean of 10 and a standard deviation (SD) of 3. These subtest scores range from 1 to19, with scores between 8 and 12 typically considered average.
|
| low visual acuity First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes |
Other: METRIC COMPARISON Tasks : Tactile PVSE test
Tactile PVSE test The tests are presented in 6 independent booklets, each of which tests a distinct skill: comparison of lengths, comparison of sizes, comparison of obliques, perception of environments, comparison of relative positions in relation to a frame and comparison of relative positions with distractors.
The assessment sheet presented in a table with the expected answers will allow you to note whether the answers are correct (rating 1) or not (rating 0). A total of the correct answers from all the sub-tests will give a total score.
Other: METRIC COMPARISON Tasks : Classic PVSE test
Classic PVSE test Use of the standardized PVSE test printed on thick white paper in 6 separate booklets each containing a subtest (length, size, oblique, middle, relative position and relative position with distractor)
The assessment sheet presented in a table with the expected answers will allow you to note whether the answers are correct (rating 1) or not (rating 0). A total of the correct answers from all the sub-tests will give a total score.
Other: Mental imagery task
This involves answering questions concerning the position or identity of 2 or 3 objects on the basis of the mental representation of a grid by auditory guidance. Each grid must be constructed mentally with the verbal description of the path and the objects encountered.
Other: Proprioceptive spatial representation tasks
16 configurations of 3 objects with direct or indirect passive exploration of their relative positions.
Each grid is presented 3 times with the following 3 questions to which the subject answers yes or no by forced choice
a single measure of the number of correct answers which will be the sum of the correct answers obtained to each of the 3 questions in the direct vs indirect condition
Other: Tasks assessing number sense based on relative positions or lengths
Pointing exercises on a digital line of 50 cm paper tape: the participant points with his finger to a position on the tape, according to the verbal request of the experimenter
Measures the intermanual gap during requests for evaluation of 5 times the wand, subtracting the length of a wand, then dividing this length by 2.
Other: WISC V Similarity and Span Test
The Wechsler Intelligence Scale for Children - Fifth Edition, Australian Standard (WISC-V) is an individually administered and comprehensive clinical instrument used to assess the general thinking and reasoning skills of children aged six years to 16 years. Test results include a Full-Scale Intelligence Quotient (IQ) score as well as age-equivalent rankings and scores for Verbal Comprehension, Visual Spatial, Fluid Reasoning, Working Memory and Processing Speed composites
Other: WISC V Arithmetic subtest
The WISC-V is an individually administered, comprehensive clinical instrument for assessing the intelligence of children. The primary and secondary subtests are on a scaled score metric with a mean of 10 and a standard deviation (SD) of 3. These subtest scores range from 1 to19, with scores between 8 and 12 typically considered average.
|
| reduced visual field First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes |
Other: METRIC COMPARISON Tasks : Tactile PVSE test
Tactile PVSE test The tests are presented in 6 independent booklets, each of which tests a distinct skill: comparison of lengths, comparison of sizes, comparison of obliques, perception of environments, comparison of relative positions in relation to a frame and comparison of relative positions with distractors.
The assessment sheet presented in a table with the expected answers will allow you to note whether the answers are correct (rating 1) or not (rating 0). A total of the correct answers from all the sub-tests will give a total score.
Other: METRIC COMPARISON Tasks : Classic PVSE test
Classic PVSE test Use of the standardized PVSE test printed on thick white paper in 6 separate booklets each containing a subtest (length, size, oblique, middle, relative position and relative position with distractor)
The assessment sheet presented in a table with the expected answers will allow you to note whether the answers are correct (rating 1) or not (rating 0). A total of the correct answers from all the sub-tests will give a total score.
Other: Mental imagery task
This involves answering questions concerning the position or identity of 2 or 3 objects on the basis of the mental representation of a grid by auditory guidance. Each grid must be constructed mentally with the verbal description of the path and the objects encountered.
Other: Proprioceptive spatial representation tasks
16 configurations of 3 objects with direct or indirect passive exploration of their relative positions.
Each grid is presented 3 times with the following 3 questions to which the subject answers yes or no by forced choice
a single measure of the number of correct answers which will be the sum of the correct answers obtained to each of the 3 questions in the direct vs indirect condition
Other: Tasks assessing number sense based on relative positions or lengths
Pointing exercises on a digital line of 50 cm paper tape: the participant points with his finger to a position on the tape, according to the verbal request of the experimenter
Measures the intermanual gap during requests for evaluation of 5 times the wand, subtracting the length of a wand, then dividing this length by 2.
Other: WISC V Similarity and Span Test
The Wechsler Intelligence Scale for Children - Fifth Edition, Australian Standard (WISC-V) is an individually administered and comprehensive clinical instrument used to assess the general thinking and reasoning skills of children aged six years to 16 years. Test results include a Full-Scale Intelligence Quotient (IQ) score as well as age-equivalent rankings and scores for Verbal Comprehension, Visual Spatial, Fluid Reasoning, Working Memory and Processing Speed composites
Other: WISC V Arithmetic subtest
The WISC-V is an individually administered, comprehensive clinical instrument for assessing the intelligence of children. The primary and secondary subtests are on a scaled score metric with a mean of 10 and a standard deviation (SD) of 3. These subtest scores range from 1 to19, with scores between 8 and 12 typically considered average.
|
Outcome Measures
Primary Outcome Measures
- percentage of correct responses [through study completion, an average of 2 year]
The experimental tasks assess allocentric spatial representations in different modalities with correct responses to spatial vs non spatial questions for the Elementary Spatial Perception test and the mental imagery test.
Eligibility Criteria
Criteria
Ages Eligible for Study:
12 Years
to 25 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
For all :
-
Aged 12 to 25
-
Participant not opposed to the research and parents do not oppose participation in the protocol for minors
For healthy volunteers (normal sighted):
- with typical visual development with correction if needed
For participant with Visual Deficiencies:
-
with congenital blindness
-
or low visual acuity (between 1/10 and 3/10)
-
or with visual field peripheral shrinkage (angle <20°).
Exclusion Criteria:
-
General knowledge and working memory skills with a standard score of less than 4
-
neurological medical history
-
Person deprived of liberty by judicial or administrative decision
-
Person subject to a legal protection measure (tutorship, curatorship)
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Hospices Civils de Lyon
Investigators
- Principal Investigator: Laure PISELLA, Dr, Equipe Trajectoire du CRNL : INSERM U1028, CNRS UMR 5292)
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Hospices Civils de Lyon
ClinicalTrials.gov Identifier:
NCT06088797
Other Study ID Numbers:
- 69HCL23_0361
First Posted:
Oct 18, 2023
Last Update Posted:
Oct 18, 2023
Last Verified:
Oct 1, 2023
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Hospices Civils de Lyon
Additional relevant MeSH terms: