Evaluation of Eye Health Benefits of Blueberry Chewable Tablets
Study Details
Study Description
Brief Summary
To assess the efficacy of blueberry chewable tablets on Eye Health
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Placebo Comparator: Placebo tablets
|
Dietary Supplement: Placebo tablets
consume 2 tablets per day for 8 weeks
|
| Experimental: Blueberry Chewable Tablets
|
Dietary Supplement: Blueberry Chewable Tablets
consume 2 tablets per day for 8 weeks
Other Names:
|
Outcome Measures
Primary Outcome Measures
- Changes of Schirmer's test [8 weeks]
Schirmer's test determines whether the eye produces enough tears to keep it moist. Units: mm (in 5minutes)
- Changes of tear meniscus height [8 weeks]
Slit lamp Ocular Surface Analyzer is utilized to measure tear meniscus height. Units: mm
- Changes of non-invasive tear break-up time (NITBUT) [8 weeks]
Ocular Surface Analyzer is utilized to measure non-invasive tear break-up time. Units: sec
- Tear break-up time (TBUT) [8 weeks]
Slit lamp ocular Surface Analyzer is utilized to measure fist tear break-up time with slit lamp. Units: sec
- Changes of accommodation [8 weeks]
Speedy-I is utilized to measure the accommodative micro fluctuation test of the ciliary muscle. Units: HFC
- Ocular Surface Disease Index (OSDI) [8 weeks]
The Ocular Surface Disease Index (OSDI) is a 12-item scale for the assessment of symptoms related to dry eye disease and their effect on vision. Units: point
Secondary Outcome Measures
- Changes of eye pressure [8 weeks]
Eye pressure is measured in millimeters of mercury (mm Hg).
- Changes of Intraocular pressure (IOP) [8 weeks]
Eye pressure is measured in millimeters of mercury (mm Hg). Units: mmHg
- Changes of Near point of convergence (NPC) [8 weeks]
RAF rule were initiated in order to normalize NPC. Record as break/recovery. Units: cm
- Changes of Stereo vision [8 weeks]
The Randot Stereotest is utilized to evaluate the depth perception. Units: sec
- Changes of binocular motor fusion [8 weeks]
The test is utilized to evaluate to assess binocular motor fusion, specifically the extent to which a patient can maintain binocular single vision (BSV) in the presence of increasing vergence demands. Units: prism
- Changes of Amplitude of accommodation (AA) [8 weeks]
The amplitude of accommodation is the maximum potential increase in optical power that an eye can achieve in adjusting its focus. It refers to a certain range of object distances for which the retinal image is as sharply focused as possible. Units: diopter
- Changes of Amplitude of Flipper facility [8 weeks]
Vergence facility (VF) was measured by using a prism flipper to evaluate the ability of the fusional vergence at near with +/-2.00 flipper. Units: cpm
- Changes of Fundus photography [8 weeks]
The fundus is the back of the eye and includes the retina, optic nerve, and retinal blood vessels.
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Adult men and women over 20 years old
-
Use 3C products over 6 hours per day
-
Symptoms of dry eyes or tired eyes
-
Tear Break-Up Time is 10 seconds less
-
No history of ocular surgery (strabismus surgery, refractive surgery etc.)
Exclusion Criteria:
-
Have systemic diseases affecting the front surface of the eyes.
-
Long-term use of drugs or eye drops that affect the condition of the front surface of the eyes
-
Long-term contact lens wear
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Chung Shan Medical University | Taichung | Taiwan | 402 |
Sponsors and Collaborators
- TCI Co., Ltd.
Investigators
- Principal Investigator: Bo-Yie Chen, Chung Shan Medical University
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- CS19152