Effects of Faba Bean Fractions as Ingredients in Novel Food Products on Glycemia, Appetite and Metabolic Control
Study Details
Study Description
Brief Summary
To describe the effect and mechanisms of action faba bean powder and fractions (protein, starch and fiber) on glucose and insulin homeostasis, food intake, satiety and metabolic regulation in young adults (18 to 30 years).
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Detailed Description
The overall objective is to describe the effect and mechanisms of action of faba bean powder and fractions (protein, starch and fiber) on glucose and insulin homeostasis, food intake, satiety and metabolic regulation in young adults (18 to 30 years). The specific objectives are to test the acute effects of different faba bean ingredient smoothie on: 1) post-prandial blood glucose, appetite, satiety hormone and insulin for 200 minutes, and 2) food intake 120 minutes following consumption of the faba bean smoothie. Two short-term acute studies will be conducted to meet these objectives. Both acute studies will follow a randomized, double blinded, balanced, repeated measures design and the same protocol; except one will have an ad libitum pizza meal (study 1), while the other will have a fixed pizza meal (study 2) at 120 minutes. Half the participants will have blood drawn by IV and the other half will be finger prick.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Placebo Comparator: Control smoothie Control smoothie with 32 g corn maltodextrin without added faba bean fractions. |
Other: Faba bean powder smoothie
Breakfast smoothie with 32 g whole faba bean powder (300g).
Other: Faba bean protein concentrate smoothie
Breakfast smoothie with 32 g faba bean protein concentrate.
Other: Faba bean starch smoothie
Breakfast smoothie with 33 g faba bean starch.
Other: Faba bean protein isolate smoothie
Breakfast smoothie with 32 g faba bean protein isolate.
|
| Experimental: Faba Bean powder smoothie Breakfast smoothie with 32 g whole faba bean powder. |
Other: Faba bean protein concentrate smoothie
Breakfast smoothie with 32 g faba bean protein concentrate.
Other: Faba bean starch smoothie
Breakfast smoothie with 33 g faba bean starch.
Other: Faba bean protein isolate smoothie
Breakfast smoothie with 32 g faba bean protein isolate.
Other: Non-pulse smoothie smoothie
Control smoothie with 32 g corn maltodextrin without added faba bean fractions.
|
| Experimental: Faba bean protein concentrate smoothie Breakfast smoothie with 32 g faba bean protein concentrate. |
Other: Faba bean powder smoothie
Breakfast smoothie with 32 g whole faba bean powder (300g).
Other: Faba bean starch smoothie
Breakfast smoothie with 33 g faba bean starch.
Other: Faba bean protein isolate smoothie
Breakfast smoothie with 32 g faba bean protein isolate.
Other: Non-pulse smoothie smoothie
Control smoothie with 32 g corn maltodextrin without added faba bean fractions.
|
| Experimental: Faba bean starch smoothie Breakfast smoothie with 33 g faba bean starch. |
Other: Faba bean powder smoothie
Breakfast smoothie with 32 g whole faba bean powder (300g).
Other: Faba bean protein concentrate smoothie
Breakfast smoothie with 32 g faba bean protein concentrate.
Other: Faba bean protein isolate smoothie
Breakfast smoothie with 32 g faba bean protein isolate.
Other: Non-pulse smoothie smoothie
Control smoothie with 32 g corn maltodextrin without added faba bean fractions.
|
| Experimental: Faba bean protein isolate smoothie Breakfast smoothie with 32 g faba bean protein isolate. |
Other: Faba bean powder smoothie
Breakfast smoothie with 32 g whole faba bean powder (300g).
Other: Faba bean protein concentrate smoothie
Breakfast smoothie with 32 g faba bean protein concentrate.
Other: Faba bean starch smoothie
Breakfast smoothie with 33 g faba bean starch.
Other: Non-pulse smoothie smoothie
Control smoothie with 32 g corn maltodextrin without added faba bean fractions.
|
Outcome Measures
Primary Outcome Measures
- blood glucose [0-200 minutes]
measured by finger prick blood samples by glucose meters
Secondary Outcome Measures
- appetite [0-200 minutes]
measured by VAS questionnaire
- satiety hormones [0- 200mins]
measured by enzyme-linked immunosorbent assay (ELISA)
- insulin [0-200mins]
measured by ELISA
- food intake [120 minutes following consumption of the faba bean smoothie]
energy intake at ad-libitum pizza meal
- physical comfort [0-200 minutes]
measured by VAS questionnaire
- energy/fatigue [0-200 minutes]
measured by VAS questionaire
Eligibility Criteria
Criteria
Inclusion Criteria:
-
healthy
-
non-smoking males
-
aged 20-30 years (min/max age)
-
a body mass index between 20 and 25 kg/m2 (the range generally accepted as ideal/healthy by Health and Welfare Canada)
Exclusion Criteria:
-
individuals diagnosed with diabetes
-
those on medication
-
breakfast skippers
-
on an energy restricted diet
-
this study excludes females because appetite and blood glucose during the female menstruation cycle changes due to fluctuations in hormones
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Richardson Centre for Functional Foods and Nutraceuticals | Winnipeg | Manitoba | Canada | R3T 2N2 |
Sponsors and Collaborators
- University of Manitoba
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- B2015:110