Facial Expression Recognition of Emotion and Categorization of Emotional Words in Gilles de la Tourette's Syndrome
Study Details
Study Description
Brief Summary
Gilles de la Tourette's syndrome is a childhood onset inherited neuropsychiatric disorder characterised by the presence of both multiple motor tics and one or more vocal tics (noises), with psychiatric and/or behaviour disorders (such as obsessive compulsive behaviour…).
This disease is associated with an dopamine system imbalance which could be responsible of a specific trouble in the recognition in some facial expression. This has been already shown in Gilles de la Tourette patients with obsessive compulsive behaviour.
We hypothesise that patients with Gilles de la Tourette's syndrome present a dysfunction of voluntary and automatic treatment of emotional information.
The main purpose of this study is to show if patients with Gilles de la Tourette's syndrome present a lack of specific facial expression recognition of emotion and determinate more precisely if this alteration involves the cortical way (high frequency way) or the under cortical way (low frequency way).
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Detailed Description
20 patients with Gilles de la Tourette's syndrome compared to 20 healthy paired volunteers.
Study progress (patients):
Inclusion visit :
Psychiatric evaluation Psychological evaluation
Ophthalmic visit
Protocol :
Facial expression recognition test Lexical decision test
Study progress (healthy volunteers):
Psychiatric evaluation Ophthalmic visit Facial expression recognition test Lexical decision test
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| 2 One group with Gilles de la Tourette's Syndrome One group with healthy paired volunteers |
Behavioral: Facial expression recognition of emotion
Facial expression recognition test Lexical decision test
|
Outcome Measures
Primary Outcome Measures
- Facial expression recognition test [% of exact responses]
Secondary Outcome Measures
- Lexical decision test [The time to respond]
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Age : >18 years
-
Patient with a Gilles de la Tourette 's syndrome such as defined in the DSMIV
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Stability of treatment >1 month
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Mini Mental State > 26
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Affiliation to social security
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Agreement of patients
Exclusion Criteria:
-
Patients with cognitive disorders, dementia, mental retardation…
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Patients with serious neurological pathologies
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Patients with a vision contrast altered.
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Patients who do not understand the words associated with an emotion
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Pregnant women
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Person who participate to an other study
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | CHU | Clermont-Ferrand | France | 63003 |
Sponsors and Collaborators
- University Hospital, Clermont-Ferrand
Investigators
- Principal Investigator: Isabelle Jalenques, PUPH, University Hospital, Clermont-Ferrand
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- CHU-0032
- RBHP 2007 Jalenques