Prediction of Fetal Macrosomia by US
Study Details
Study Description
Brief Summary
Fetal macrosomia defined as birth weight above 90th centile ,macrosomia occurs in 42-62%of pregnancy complicated by type 1 diabetes mellitus ,in 30-56% of pregnancy complicated by type 2 diabetes mellitus .
-The delivery of macrosomic infant has potentially severe consequence for both the newborn and mother .Increased birth weight increase the risk in the fetus of shoulder dystocia and premature brachial plexus injury ,and those infant weighing above 4500g are at increased risk for neonatal morbidity ,including the need for assisted ventilation and meconium aspiration .Maternal complication result from operative delivery and include postpartum hemorrhage ,third or fourth degree laceration and postpartum infection .
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Detailed Description
Estimated fetal body weight is needed especially when head measurement is impossible whenever the fetal head is positioned low in pelvic brim .A convenient method for estimating fetal body weight without head measurement was thus required .
-The human placenta develop with the principal function of providing nutrients and oxygen to the fetus ,adequate fetal growth and subsequent normal birth weight depend on normal placenta .
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Diabetes mellitus Pregnant women with diabetes mellitus will be examined by us to measures placental volume and thickness ,IV thickness and HbA1c |
Diagnostic Test: Ultrasound
Ultrasound will be done to every pregnant lady
Diagnostic Test: HbA1c level in blood
a blood sample will be taken to measure HbA1c level
|
| control group Pregnant women with no medical disorders will be examined by us to measures placental volume and thickness ,IV thickness and HbA1c |
Diagnostic Test: Ultrasound
Ultrasound will be done to every pregnant lady
Diagnostic Test: HbA1c level in blood
a blood sample will be taken to measure HbA1c level
|
Outcome Measures
Primary Outcome Measures
- the number of paticipants who will have babies with macrosomias [within a week from delivery]
To detect number of fetuses who will develop macrosomia
Eligibility Criteria
Criteria
Inclusion Criteria:
- 1.Singleton gestational 2.Gestational age over 16-20 weeks 3.Intact membrane 4.Normal umbilical morphology (two arteries and one vein )
Exclusion Criteria:
-
The presence of fetal congenital anomaly .
-
Multifetal pregnancy.
-
Maternal chronic disease (hypertension, renal disease ,and pulmonary disease ,etc.)
-
Patient with a diagnosis such as oligohydramnios ,preeclampsia and intrauterine growth retardation .
-
Patient who used cigarette or alcohol during pregnancy.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Algazeerah | Giza | Egypt |
Sponsors and Collaborators
- Aljazeera Hospital
- Kasr El Aini Hospital
- National Research Centre, Egypt
Investigators
- Principal Investigator: Mahmoud Alalfy, M.s.c, Algazeerah hospital -Location (Giza -Egypt ) and National Research centre egypt
- Study Chair: Ahmed samy, M.D, kasraliny hospital- Aljazeerah hospital
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- macrosomia prediction