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A Follow-up Colonoscopy Examination in Patients Who Had Previously Undergone Screening Colonoscopy

Sponsor
Chinese University of Hong Kong (Other)
Overall Status
Completed
CT.gov ID
NCT00280332
Collaborator
(none)
560
Enrollment
1
Location
20
Duration (Months)
27.9
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

  • To determine the prevalence of colonic neoplasm in patients who had previously undergone screening colonoscopy

  • To determine the optimal time interval for re-screening in average risk individuals

  • To determine potential baseline characteristics that predicts adenoma recurrence

Condition or Disease Intervention/Treatment Phase
  • Procedure: colonoscopy

Detailed Description

Colorectal cancer (CRC) is the second commonest cancer in Hong Kong, and tends to be increasing. Screening for colorectal cancer can reduce the cancer incidence and mortality by detecting early lesions. However, the best interval for a follow up colonoscopy, particularly for those with normal baseline colonoscopy, remains largely unknown.

This study aim to determine the prevalence of colonic neoplasm in average-risk patients who had previously undergone screening colonoscopy and the optimal time interval for re-screening.

Study Design

Study Type:
Observational
Actual Enrollment :
560 participants
Observational Model:
Case-Control
Time Perspective:
Prospective
Official Title:
A Follow-up Colonoscopy Examination in Patients Who Had Previously Undergone Screening Colonoscopy
Study Start Date :
Mar 1, 2006
Actual Primary Completion Date :
Nov 1, 2007
Actual Study Completion Date :
Nov 1, 2007

Arms and Interventions

Arm Intervention/Treatment
A

colonic adenoma

Procedure: colonoscopy
proform a follow up colonoscopy in the 5 year period from index colonoscopy
Other Names:
  • follow up colonoscopy

    		•
    B

    colonic without adenoma

    Procedure: colonoscopy
    proform a follow up colonoscopy in the 5 year period from index colonoscopy
    Other Names:
  • follow up colonoscopy

    		•

    Outcome Measures

    Primary Outcome Measures

    1. The prevalence of advanced colonic adenoma in the re-screening population [5 year from index colonoscopy]

    Secondary Outcome Measures

    1. The time to adenoma adenoma development according to different baseline characteristics of patients and colonoscopy findings [5 years from index colonoscopy]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    50 Years to 75 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:

    • Subjects who are previously participated in one of our two screening colonoscopy studies [Sung, Gastroenterol 2003; Leung, AJG 2004]

    • Asymptomatic on first screening colonoscopy

    • Age>50and <75

    • No family history of CRC

    • No other colonoscopy except the baseline screening colonoscopy

    Exclusion Criteria:

    • Subjects who refused consent

    • Subjects who are not warrant follow up colonoscopy

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Endoscopy Center, Prince of Wales Hospital Hong Kong (SAR) China

    Sponsors and Collaborators

    • Chinese University of Hong Kong

    Investigators

    • Principal Investigator: Wai K Leung, MD, CUHK

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    , ,
    ClinicalTrials.gov Identifier:
    NCT00280332
    Other Study ID Numbers:
    • FUC
    First Posted:
    Jan 23, 2006
    Last Update Posted:
    May 12, 2008
    Last Verified:
    May 1, 2008
    Keywords provided by , ,
    colonic adenoma, colonic advanced neoplasm
    Additional relevant MeSH terms:
    Colonic Neoplasms

    Study Results

    No Results Posted as of May 12, 2008