Frequency of Parasite Infestation in Patients With Chronic Spontaneous Urticaria

• Sponsor: University Hospital, Basel, Switzerland (Other)
• Overall Status: Completed
• CT.gov ID: NCT04314999
• Collaborator: (none)
• Enrollment: 57
• Location: 1
• Actual Duration (Months): 4
• Patients Per Site Per Month: 14.3

Study Details

Study Description

Brief Summary

The goal of this study is to describe the prevalence and the type of parasite in patients with a chronic spontaneous urticaria as well as to describe the associations between parasitic disease and the characteristics of the patients, for example eosinophilia.

Condition or Disease	Intervention/Treatment	Phase
Chronic Spontaneous Urticaria; Parasitic Disease	Diagnostic Test: Examination of stool samples

Study Design

• Study Type: Observational
• Actual Enrollment: 57 participants
• Observational Model: Case-Only
• Time Perspective: Retrospective
• Official Title: Häufigkeit Der Infestation Mit Parasiten Bei Patienten Mit Chronisch Spontaner Urtikaria, Eine Retrospektive Datenanalyse
• Actual Study Start Date: Jun 1, 2019
• Actual Primary Completion Date: Sep 30, 2019
• Actual Study Completion Date: Sep 30, 2019

Arms and Interventions

Arm	Intervention/Treatment
Patients diagnosed with a chronic spontaneous urticaria Patients with a chronic spontaneous urticaria who were being treated at the allergology of the university hospital Basel between the 1st of June and the 30th of September	Diagnostic Test: Examination of stool samples; Tests for diagnosis of parasitic diseases

Outcome Measures

Primary Outcome Measures

1. Number of patients with parasite infestation [Patients with a chronic spontaneous urticaria that were treated at the University hospital basel between the 1st of June 2019 and the 30th of September 2019]

   assess number of patients with chronic spontaneous urticaria that have a parasite infestation (Analysis of stool samples by the Swiss Tropical and Public Health Institute (TPH), Basel)

2. Most common parasite subgroup [Patients with a chronic spontaneous urticaria that were treated at the University hospital basel between the 1st of June 2019 and the 30th of September 2019]

   subtype determination from stool samples was performed by the Swiss TPH, Basel by polymerase chain reaction (PCR)

Secondary Outcome Measures

1. Correlation between migration Background/ travel history of the patients and parasite infestation [Patients with a chronic spontaneous urticaria that were treated at the University hospital basel between the 1st of June 2019 and the 30th of September 2019]

   examine travel history and migration background of patients

2. Correlation between gastrointestinal complaints of the patients and parasite infestation [Patients with a chronic spontaneous urticaria that were treated at the University hospital basel between the 1st of June 2019 and the 30th of September 2019]

   anamnesis of the patients

Eligibility Criteria

Criteria

• Ages Eligible for Study: 17 Years and Older
• Sexes Eligible for Study: All

Inclusion Criteria:

• Diagnosis of a chronic spontaneous urticaria

• Age: 17 years old and up

Exclusion Criteria:

• No diagnosis of a chronic spontaneous urticaria

• Age: younger than 17 years

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	University Hospital Basel	Basel		Switzerland	4031

Sponsors and Collaborators

• University Hospital, Basel, Switzerland

Investigators

• Principal Investigator: Esther Steveling-Klein, Dr. med., Allergology, University Hospital Basel

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: University Hospital, Basel, Switzerland
• ClinicalTrials.gov Identifier: NCT04314999
• Other Study ID Numbers: 2019-01953;sp20Steveling2
• First Posted: Mar 19, 2020
• Last Update Posted: Mar 19, 2020
• Last Verified: Mar 1, 2020

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Keywords provided by University Hospital, Basel, Switzerland: Chronic Spontaneous Urticaria; Parasitic disease
• Additional relevant MeSH terms: Parasitic Diseases; Urticaria; Chronic Urticaria

Study Results

No Results Posted as of Mar 19, 2020