Low Fructose Diet in Diabetes Type 2

• Sponsor: National Nutrition and Food Technology Institute (Other)
• Overall Status: Unknown status
• CT.gov ID: NCT03352596
• Collaborator: (none)
• Enrollment: 48
• Arms: 2
• Anticipated Duration (Months): 10.9

Study Details

Study Description

Brief Summary

Diabetes is one of the most common and chronic diseases in the world, with the prevalence and incidence of this disease rising in most societies, especially in Iran. Suitable treatments for type 2 diabetes include changing lifestyle with exercise, nutrition, and drug use. New research suggests that added sugar, especially fructose, is the main trigger for diabetes and pre-diabetes even more potent than other carbohydrates. Fructose has a low glycemic index (23μg =) and slowly increases blood glucose levels. Therefore, it is thought that replacing fructose instead of glucose can have a positive effect on glycemic control of diabetic patients..

Condition or Disease	Intervention/Treatment	Phase
Fructose Metabolism Disorder	Other: low frutose diet	N/A

Study Design

• Study Type: Interventional
• Actual Enrollment: 48 participants
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Masking: Double (Participant, Care Provider)
• Primary Purpose: Supportive Care
• Official Title: Effects of Low Fructose Diet on Glycemic Control in Patients With Type 2 Diabetes
• Actual Study Start Date: Jan 1, 2017
• Actual Primary Completion Date: Oct 1, 2017
• Anticipated Study Completion Date: Nov 30, 2017

Arms and Interventions

Arm	Intervention/Treatment
Experimental: intervention group Eight weeks of low fructose diet with a maximum of 12 g of fructose	Other: low frutose diet
No Intervention: control group Eight weeks of regular diabetic diet with a 15%pro 30%fat 55%CHO

Outcome Measures

Primary Outcome Measures

1. fasting blood suger(FBS) [8 weeks]

2. Homeostatic model assessment and insulin resistance(HOMA-IR) [8weeks]

3. insulin [8 weeks]

Secondary Outcome Measures

1. Triglyceride [8 weeks]

2. Total cholestrole [8 weeks]

3. LDL-C [8 weeks]

4. HDL-C [8 weeks]

5. Blood pressure [8 weeks]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 40 Years to 70 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

1. Age of 70-40 years

2. body mass index(BMI) between 18.5 and 27

3. Type 2 diabetes People who only control their diabetes by using glucose lowering tablets Type 2 diabetes (1 to 10 years)

Exclusion Criteria:

1. Pregnancy and lactation

2. Thyroid gland disorders

3. Kidney disease and inflammation

4. Follow the weight loss regimen 6 months before starting the study

5. Usage of fatty and fatty foods, fiber powder Vitamin A Mineral Supplements, Omega 3

6. Taking glucocorticoid drugs and non-steroidal anti-inflammatory drugs

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

• National Nutrition and Food Technology Institute

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Dr Azita Hekmatdoost, Principal Investigator, National Nutrition and Food Technology Institute
• ClinicalTrials.gov Identifier: NCT03352596
• Other Study ID Numbers: 93567
• First Posted: Nov 24, 2017
• Last Update Posted: Nov 24, 2017
• Last Verified: Aug 1, 2017

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Additional relevant MeSH terms: Metabolic Diseases

Study Results

No Results Posted as of Nov 24, 2017