Functional Study of Metabolites in Patients With Aortic Dissection

Sponsor

Shenzhen People's Hospital (Other)

Overall Status

Unknown status

CT.gov ID

NCT04450433

Collaborator

(none)

Enrollment

Location

Anticipated Duration (Months)

0.1

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Research on metabolites in patients with aortic dissection, with a view to finding products with high or low metabolism in patients with aortic dissection, looking for metabolic factors related to the onset of aortic dissection, and further verifying the role of metabolic factors in disease through functional verification The role of formation, and ultimately explore the early screening of potential aortic dissection patients

Condition or Disease	Intervention/Treatment	Phase
Aortic Dissection	Diagnostic Test: aortic dissection and healthy people

Study Design

Study Type:

Observational

Anticipated Enrollment :

1 participants

Observational Model:

Case-Control

Time Perspective:

Prospective

Official Title:

Functional Study of Metabolites in Patients With Aortic Dissection

Actual Study Start Date :

Nov 1, 2019

Anticipated Primary Completion Date :

Jul 30, 2020

Anticipated Study Completion Date :

Oct 30, 2020

Arms and Interventions

Arm	Intervention/Treatment
Baseline table of patients	Diagnostic Test: aortic dissection and healthy people Differential expression of metabolites in patients with aortic dissection and healthy people
Differential metabolites of two groups of control patients	Diagnostic Test: aortic dissection and healthy people Differential expression of metabolites in patients with aortic dissection and healthy people
Functional verification of differential metabolites	Diagnostic Test: aortic dissection and healthy people Differential expression of metabolites in patients with aortic dissection and healthy people

Arm

Intervention/Treatment

Baseline table of patients

Diagnostic Test: aortic dissection and healthy people

Differential expression of metabolites in patients with aortic dissection and healthy people

Differential metabolites of two groups of control patients

Diagnostic Test: aortic dissection and healthy people

Differential expression of metabolites in patients with aortic dissection and healthy people

Functional verification of differential metabolites

Diagnostic Test: aortic dissection and healthy people

Differential expression of metabolites in patients with aortic dissection and healthy people

Outcome Measures

Primary Outcome Measures

Differential expression of metabolites in two groups of patients [2019-11----2021.01]
Differential expression of metabolites in the two groups of patients, looking for metabolic factors related to the incidence of aortic dissection, and further verifying the function of metabolites through functional methods, with a view to finding high-risk metabolic factors for patients with aortic dissection

Eligibility Criteria

Criteria

Ages Eligible for Study:

30 Years to 80 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

patients with Aortic dissection

Exclusion Criteria:

Sepsis

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Shenzhen People's Hospital	Shenzhen	Guangdong	China	518020

Sponsors and Collaborators

Shenzhen People's Hospital

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Shenzhen People's Hospital

ClinicalTrials.gov Identifier:

NCT04450433

Other Study ID Numbers:

Liuhuadong's Research Group

First Posted:

Jun 29, 2020

Last Update Posted:

Jun 29, 2020

Last Verified:

Jun 1, 2020

Individual Participant Data (IPD) Sharing Statement:

Undecided

Plan to Share IPD:

Undecided

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Additional relevant MeSH terms:

Aneurysm, Dissecting

Study Results

No Results Posted as of Jun 29, 2020