RECOVIDS: Functional Recovery From Acute Respiratory Distress Syndrome (ARDS) Due to COVID-19: Influence of Socio-Economic Status
Study Details
Study Description
Brief Summary
In this study, the investigators are attempting to evaluate the influence of socio-economic factors on the functional recovery (physical and psychological) of patients who developed ARDS after a COVID-19 infection, with the aim of offering personalized medical and social follow-up and support measures in order to avoid medium- and long-term complications, which can result in handicaps, reduced quality of life, and a higher risk of death.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Patient Patient hospitalized in ICU for PCR-proven SARS-COV-2 infection |
Other: Paraclinical examination
Respiratory functional tests
Other: Clinical Examination
Clinical Examination
Other: Semi-directive interview
By phone
Other: quality of life questionnaires
SF36, VSRQ, IESR, HADS
|
Outcome Measures
Primary Outcome Measures
- Respiratory sequelae 6 months after resuscitation. [Through study completion, an average of 6 months]
Defined by the presence of at least one of the following : An alteration of the alveolar-capillary diffusion of CO <80% of the predicted normal values And/or a forced vital capacity <80% of predicted normal values and/or O2 desaturation in the 6-minute walk test And/or pulmonary parenchymatous disease with fibrosis in tomodensitometry.
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Inpatient in ICU for PCR-proven SARS-VOC-2 infection regardless of specimen type
-
Patient who received a chest CT scan in the initial phase of management (either just before or during hospitalization in the intensive care unit)
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Patient who has received invasive or non-invasive ventilatory support, or humidified and heated high-flow oxygen (HFO).
-
ARDS meeting the criteria of the 2012 Berlin definition. For patients who have received only HFO, a flow rate at least equal to 50L/minute with a FiO2 strictly greater than 50% with a PaO2/FiO2 ratio less than or equal to 200 will be required for inclusion.
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Patient who gave oral consent after being informed about the conduct of this study.
Exclusion Criteria:
-
Patient with limited autonomy prior to hospitalization in limited intensive care unit: walking distance of less than 50 meters, WHO classification status 3 and 4.
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Patient with a history of chronic respiratory failure as defined by the use of long-term oxygen therapy or non-invasive home ventilation, excluding patients with SAS and/or hypoventilation obesity syndrome.
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Patient with a history of central or peripheral neurological conditions limiting the patient's motor autonomy and the performance on gait tests or Pulmonary function Tests
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Patient refusing to participate
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Patient < 18 years of age
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Patient not affiliated or not benefiting from national health insurance
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Patient under guardianship, curatorship or protected adult
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Patient unable to understand and consent to the research protocol
SECONDARY EXCLUSION CRITERIA
-
Patient not showing up for visit at M6
-
Patients who have not had all the examinations necessary to evaluate the main endpoint (Spirometry, DLCO, TM6 and CT)
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Chu Dijon Bourgogne | Dijon | France | 21000 |
Sponsors and Collaborators
- Centre Hospitalier Universitaire Dijon
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- QUENOT 2020