The Model for End-Stage Liver Disease Sodium (MELD-Na) Score in Non-cirrhotic Patients With Gastric Cancer
Study Details
Study Description
Brief Summary
Gastric cancer is the fifth most common cancer worldwide. Gastrectomy with lymphadenectomy is still the most effective treatment modality, depending on the stage and location. Despite many radiological, surgical and anesthetic innovations, serious complications such as anastomotic leakage, intra-abdominal abscesses, wound complications are seen secondary to gastrectomy. Many clinical studies have been conducted to prevent and predict these complications.
The Model for End-Stage Liver Disease (MELD) score, in which bilirubin, international normalized ratio (INR) and serum creatinine values were used to determine surgical risks in patients scheduled for liver transplantation. Latter developed by adding serum sodium (Na) to the formula. The MELD-Na score is used to predict postoperative complications in non-cirrhotic patients because of its simple and easy calculation.Moreover, The Meld-Na score was later used to predict complications for surgical procedures other than liver surgery such as colorectal surgery.
In this study, we aimed to investigate the importance of the Meld-Na score in predicting the perioperative and postoperative outcomes in patients with gastric cancer.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Group 1 Patients with postoperative complications |
Other: MELD-Na score
MELD-Na scores will be compared between the groups
|
| Group 2 Patients without postoperative complications |
Other: MELD-Na score
MELD-Na scores will be compared between the groups
|
Outcome Measures
Primary Outcome Measures
- MELD-Na score difference between the groups [30 days]
Importance of MELD-Na score in predicting postoperative complications in patients with gastric cancer
Eligibility Criteria
Criteria
Inclusion Criteria:
- Patients undergoing gastrectomy due to gastric cancer
Exclusion Criteria:
-
Patients with pulmonary, hepatic and renal disfunctions,
-
Patients with diagnosed with a different cancer in the last 5 years and
-
Pregnant patients
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Istanbul Training and Research Hospital | Istanbul | Turkey | 34029 |
Sponsors and Collaborators
- Istanbul Training and Research Hospital
Investigators
- Principal Investigator: Cihad Tatar, MD, Istanbul Training and Research Hospital
Study Documents (Full-Text)
None provided.More Information
Publications
- Coakley KM, Sarasani S, Prasad T, Steele SR, Paquette I, Heniford BT, Davis BR. MELD-Na Score as a Predictor of Anastomotic Leak in Elective Colorectal Surgery. J Surg Res. 2018 Dec;232:43-48. doi: 10.1016/j.jss.2018.04.012. Epub 2018 Jul 2.
- Schlosser KA, Kao AM, Zhang Y, Prasad T, Kasten KR, Davis BR, Heniford BT, Colavita PD. MELD-Na score associated with postoperative complications in hernia repair in non-cirrhotic patients. Hernia. 2019 Feb;23(1):51-59. doi: 10.1007/s10029-018-1849-2. Epub 2018 Nov 16.
- Yasri S, Wiwanitkit V. MELD-Na score and postoperative complications in hernia repair. Hernia. 2019 Aug;23(4):823. doi: 10.1007/s10029-019-01886-z. Epub 2019 Jan 22.
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