Genetic Evaluation of AAAS Gene in Early-Onset Achalasia and Alacrima Patients
Sponsor
Asan Medical Center (Other)
Overall Status
Completed
CT.gov ID
NCT00856921
Collaborator
(none)
19
11
Study Details
Study Description
Brief Summary
The AAAS gene has been known to cause achalasia, alacrima, adrenal abnormalities and a progressive neurological syndrome. A considerable proportion of achalasia patients have been known to show alacrima (decreased secretion of tears). However, the genetic mechanism between achalasia and alacrima has not been defined yet. The investigators postulated that some proportions of early-onset achalasia could be correlated with AAAS gene; thus, the investigators aimed to investigate the relationship between the AAAS gene and early-onset achalasia.
Study Design
Study Type:
Observational
Actual Enrollment
:
19 participants
Observational Model:
Case-Only
Time Perspective:
Retrospective
Official Title:
To Find Out the Genetic Relationship Between the Early-Onset Achalasia and AAAS Gene
Study Start Date
:
Apr 1, 2008
Actual Primary Completion Date
:
Jan 1, 2009
Actual Study Completion Date
:
Mar 1, 2009
Outcome Measures
Primary Outcome Measures
- Genetic relationship between achalasia and AAAS gene []
Eligibility Criteria
Criteria
Ages Eligible for Study:
N/A
and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
-
early age onset
-
primary achalasia patient
-
less than 35 years old
Exclusion Criteria:
- secondary achalasia patients
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Asan Medical Center
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
,
,
ClinicalTrials.gov Identifier:
NCT00856921
Other Study ID Numbers:
- AAASachalasia
First Posted:
Mar 6, 2009
Last Update Posted:
Mar 6, 2009
Last Verified:
Mar 1, 2009
Keywords provided by ,
,
Additional relevant MeSH terms: