GAP: The Genetic and Affective Prediction Study

Sponsor

St. Olavs Hospital (Other)

Overall Status

Completed

CT.gov ID

NCT02625818

Collaborator

Norwegian University of Science and Technology (Other)

400

Enrollment

Location

Actual Duration (Months)

6.7

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

A major proportion of patients admitted to psychiatric acute and emergency departments have symptoms, behaviors or function influenced by implicit or explicit suicidal intention (tendency towards self-harm, or suicide attempt). There is an increased risk of suicide in the acute phase during in-patient stay and after discharge. At present there is no satisfactory tool to predict post-discharge suicide risk.

Multidimensional rating is expected to have better predictive properties than one-dimensional rating for suicidal behavior during in -patient stay and two years after discharge. Multidimensional rating assesses anxiety, panic, agitation, suicidal thoughts and ideations, as well as therapist's reactions during interviews. In the present study the predictive properties of two rating scales for suicidal behavior during in-patient stay and two years after will be compared. One of these is a multidimensional scale: "Multidimensional Assessment of Suicide Risk" (MARIS).

Condition or Disease	Intervention/Treatment	Phase
Mental Disorders

Study Design

Study Type:

Observational

Actual Enrollment :

400 participants

Observational Model:

Case-Only

Time Perspective:

Prospective

Official Title:

The Genetic and Affective Prediction Study

Actual Study Start Date :

Jan 1, 2016

Actual Primary Completion Date :

Jan 1, 2020

Actual Study Completion Date :

Jan 1, 2021

Arms and Interventions

Arm	Intervention/Treatment
acute psychiatric condition

Outcome Measures

Primary Outcome Measures

self-inflicted, potentially injurious behavior with intention to die defined as acts needing attendance by physician [2 weeks]
during in-patient stay

Secondary Outcome Measures

suicide [2 years after discharge]

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

acute agitated condition
informed consent

Exclusion Criteria:

Drug abuse
in-patient stay for a fixed time at regular intervals

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	St Olavs Hospital, Østmarka psychiatric department	Trondheim		Norway

Sponsors and Collaborators

St. Olavs Hospital
Norwegian University of Science and Technology

Investigators

Study Director: Randolf Terje Vågen, St Olavs Hospital, Division of Mental Health Care
Study Director: Nanna Sønnichsen Kayed, Department of Mental Health, Faculty of Medicine and Health, NTNU