ALAFOR: Genetic Determinant of Foveolar Hypoplasia in Parents of Albinos Children
Sponsor
Fondation Ophtalmologique Adolphe de Rothschild (Other)
Overall Status
Completed
CT.gov ID
NCT03959605
Collaborator
(none)
48
1
32.8
1.5
Study Details
Study Description
Brief Summary
Fovea plana could be the phenoyipic translation of a genetic anomaly in one of the genes identified in albinisme
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Study Type:
Observational
Actual Enrollment
:
48 participants
Observational Model:
Case-Control
Time Perspective:
Prospective
Official Title:
Genetic Determinant of Foveolar Hypoplasia in Parents of Albinos Children
Actual Study Start Date
:
Jan 6, 2019
Actual Primary Completion Date
:
Feb 2, 2021
Actual Study Completion Date
:
Oct 1, 2021
Outcome Measures
Primary Outcome Measures
- Number of genetics variants [1 month]
among the genes involved in albinism, identification of those presents in parents of children with albinism
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
-
children with albinism
-
father and mother of children with albinism
Exclusion Criteria:
-
sign of albinism except fovea plana in father or mother of children with albinism
-
ophthalmological abnormalities making access to the fundus with OCT impossible
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Fondation A de Rothschild | Paris | France | 75019 |
Sponsors and Collaborators
- Fondation Ophtalmologique Adolphe de Rothschild
Investigators
- Principal Investigator: Martine MAUGET FAYSSE, Fondation A. de Rothschild
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Fondation Ophtalmologique Adolphe de Rothschild
ClinicalTrials.gov Identifier:
NCT03959605
Other Study ID Numbers:
- MMT_2019_2
First Posted:
May 22, 2019
Last Update Posted:
Oct 21, 2021
Last Verified:
Oct 1, 2021
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms: