Efficacy of Eco-Friendly Toothpaste Tablets Versus Conventional Toothpaste Using PI and GI Index
Study Details
Study Description
Brief Summary
Objectives: To assess the change in gingival index (GI) and plaque index (PI) when comparing the use of toothpaste tablets to conventional toothpaste.
Methods: 40 participants were randomized into two groups: Colgate's toothpaste tablets (T) and Colgate's Cavity Protection toothpaste (C). Both groups utilized their assigned dentifrice for 2 weeks. A pre and post-assessment measured the GI and PI index. A questionnaire on the use of the product was distributed.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: Toothpaste Tablet Subjects are instructed to use one toothpaste tablet for brushing. Brushing is recommended twice daily for two minutes. |
Device: Toothpaste Tablet
Colgate Anywhere Toothpaste Tablets
|
| Active Comparator: Conventional Toothpaste Subjects are instructed to use the toothpaste for brushing. Brushing is recommended twice daily for two minutes. |
Device: Conventional Toothpaste
Colgate Cavity Protection
|
Outcome Measures
Primary Outcome Measures
- Plaque Index Score [Change between baseline at visit 1 and visit 2, two weeks post baseline.]
Plaque was scored according to the Turesky modification of the Quigley-Hein Plaque Index. Each tooth was divided into six surfaces, three facial and three lingual, as follows: 1) mesio-facial; 2) mid-facial; 3) disto-facial; 4) mesio-lingual; 5) mid-lingual; and 6) disto-lingual. Teeth included in the scoring were: #3, 7, 12, 19, 23, 28. Plaque was disclosed and scored on each tooth surface according to the following criteria: 0: No plaque. Separate flecks of plaque at the cervical margin. A thin, continuous band of plaque (up to 1 mm) at the cer- vical margin. A band of plaque wider than 1 mm but covering less than 1/3 of the side of the crown of the tooth. Plaque covering at least 1/3, but less than 2/3 of the side of the crown of the tooth. Plaque covering 2/3 or more of the side of the crown of the tooth. Subject-wise scores were determined by averaging the values obtained over all scorable surfaces in the mouth.
- Gingival Index Score [Change between baseline at visit 1 and visit 2, two weeks post baseline.]
Gingivitis was scored according to the Löe-Silness Gingival Index. Each tooth was divided into six surfaces, three facial and three lingual, as follows: 1) mesio-facial; 2) mid-facial; 3) disto-facial; 4) mesio-lingual; 5) mid-lingual; and 6) disto-lingual. Teeth included in the scoring were: #3, 7, 12, 19, 23, 28. The gingiva adjacent to each tooth surface was scored as follows: 0 = Absence of inflammation. = Mild inflammation-slight change in color and little change in texture. = Moderate inflammation-moderate glazing, redness, edema, and hypertrophy. = Severe inflammation-marked redness and hypertrophy. Tendency for spontaneous bleeding. Subject-wise scores were determined by averaging the values obtained over all scorable surfaces in the mouth.
Secondary Outcome Measures
- Subject Perception of Product Use [Visit 2 two weeks post study enrollment]
This is a composite measurement based on questionnaire response. Subject swill answer 7 questions related to cleanliness, flavor, ease of use, eco-friendliness, willingness to switch, satisfaction, texture.
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Subjects are 18 years or older;
-
Subjects who will comply with study protocol;
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Subjects who can read and understand the consent form;
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Subjects available during the study period;
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Subjects have more than 20 teeth.
Exclusion Criteria:
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Subjects who are pregnant and/or nursing;
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Subjects under the age of 18.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Loma Linda University | Loma Linda | California | United States | 92350 |
Sponsors and Collaborators
- Loma Linda University
Investigators
- Principal Investigator: So Ran Kwon, DDS, MS, PhD, Loma Linda University
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 5220342