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Post-prandial Glucose Response From Phytochemical Rich Potato Products

Sponsor
Purdue University (Other)
Overall Status
Completed
CT.gov ID
NCT03066713
Collaborator
USDA Beltsville Human Nutrition Research Center (U.S. Fed)
24
Enrollment
1
Location
4
Arms
4.8
Actual Duration (Months)
5
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Assess the impact of high antioxidant potato products on postprandial glycemic response and subsequent appetite and food intake.

Condition or Disease Intervention/Treatment Phase
  • Other: Skin Off French Fry
  • Other: Skin On French Fry
  • Other: Hash brown
  • Other: Carbohydrate control
 N/A

Detailed Description

Preliminary results from anthocyanin rich potato products suggest that a reduced postprandial glycemic response might be expected from certain types of potato products and that phenolic antioxidants may play a critical role in predicting the physiological response from potato products. Further, if consumed early in the day, such as at breakfast, a reduced glycemic response may serve to mitigate appetite and food consumption later in the day. Investigators aim to better understand how characteristics of commercial potato products (i.e. frozen potato products) with different phenolic profiles and content, may alter postprandial glycemic response and subsequent appetitive behavior. Specifically, investigators will assess the glycemic response from a serving of potato products in the morning using continuous glucose monitoring. Further, appetite and subsequent food consumption later in the day will be assessed through appetite logs and continuous glucose monitoring.

Study Design

Study Type:
Interventional
Actual Enrollment :
24 participants
Allocation:
Randomized
Intervention Model:
Crossover Assignment
Masking:
None (Open Label)
Primary Purpose:
Basic Science
Official Title:
Post-prandial Glucose Response From Phytochemical Rich Potato Products
Actual Study Start Date :
Jan 31, 2017
Actual Primary Completion Date :
Jun 25, 2017
Actual Study Completion Date :
Jun 25, 2017

Arms and Interventions

Arm Intervention/Treatment
Experimental: Experimental: A

Skin On French Fry - breakfast Skin On French Fry - lunch Mashed Potatoes - dinner

Other: Skin On French Fry
Skin On French Fries will be provided at breakfast and lunch
Experimental: Experimental: B

Skin Off French Fry - breakfast Skin Off French Fry - lunch Mashed Potatoes - dinner

Other: Skin Off French Fry
Skin Off French Fries will be provided at breakfast and lunch
Experimental: Experimental: C

Hash brown - breakfast Hash brown - lunch Mashed Potato - dinner

Other: Hash brown
Hash brown potatoes will be provided at breakfast and lunch.
Experimental: Experimental: D

Pancake - breakfast Pretzels - lunch Macaroni - dinner

Other: Carbohydrate control
A pancake will be provided at breakfast, and pretzels will be provided at lunch.

Outcome Measures

Primary Outcome Measures

  1. Change in Blood Glucose over 24 hours [24 hours]

    Samples taken every 5 minutes for 24 hours by a continuous glucose monitor

Secondary Outcome Measures

  1. Appetite [Every hour for 24 hours]

    Questionnaire on hunger, fullness, desire to eat, prospective consumption, thirst taken hourly on the same day as the feeding intervention

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 50 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • BMI 18.5-25, male or female
Exclusion Criteria:
  • BMI outside 18.5-25

Contacts and Locations

Locations

Site City State Country Postal Code
1 Purdue University West Lafayette Indiana United States 47906

Sponsors and Collaborators

  • Purdue University
  • USDA Beltsville Human Nutrition Research Center

Investigators

  • Principal Investigator: Richard D Mattes, PhD, Purdue University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Richard Mattes, Principle Investigator, Purdue University
ClinicalTrials.gov Identifier:
NCT03066713
Other Study ID Numbers:
  • 055-046
First Posted:
Feb 28, 2017
Last Update Posted:
Jan 18, 2018
Last Verified:
Jan 1, 2018
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No

Study Results

No Results Posted as of Jan 18, 2018