ThaiScalpBx: Hair Counts From Vertical and Horizontal Sections of Scalp Biopsy SPecimens in Thai Population With Alopecia

• Sponsor: Siriraj Hospital (Other)
• Overall Status: Unknown status
• CT.gov ID: NCT01651689
• Collaborator: (none)
• Enrollment: 50
• Location: 1
• Duration (Months): 31
• Patients Per Site Per Month: 1.6

Study Details

Study Description

Brief Summary

Hair disorders, expecialy scarring alopecia were diagnosed by scalp biopsy specimens in horizontal and vertical sections.(1-4) Data on hair density in Thais are lacking, although in Asians have more fewer hairs than whites.(5-7)Howevery, previous study from East Asian just had only one study and the data was more differently from West Asian and whites. Then this study was performed to evaluate hair density in Thais, and compared to previous study.

Condition or Disease	Intervention/Treatment	Phase
Alopecia

Study Design

• Study Type: Observational
• Anticipated Enrollment: 50 participants
• Observational Model: Case-Only
• Time Perspective: Prospective
• Official Title: Hair Counts From Vertical and Horizontal Sections of Scalp Biopsy SPecimens in Thai Population With Alopecia
• Study Start Date: Oct 1, 2010
• Anticipated Primary Completion Date: Apr 1, 2013
• Anticipated Study Completion Date: May 1, 2013

Arms and Interventions

Arm	Intervention/Treatment
Scalp biopsy Subjects are on scadule list for hair transplantation in Siriraj hospital. Scalp biopsy with punch biopsy No.4 Scalp biopsy by punch biopsy No.4 at occipital area was done in subjects who have hair transplantaion.

Outcome Measures

Primary Outcome Measures

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• Thai

• Age >= 18 years

• Diagnosis alopecia and on list for hair transplantation in Siriraj hospital

Exclusion Criteria:

• Alopecia areata or positive hair pulling test

• Underlying disease : DM, chronic renal failure, chronic liver disease

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Siriraj hospital	Bangkok		Thailand	10700

Sponsors and Collaborators

• Siriraj Hospital

Investigators

• Principal Investigator: Rattapon Thuangtong, MD, Department of Dermatology, Siriraj hospital, Faculty of Medicine, Mahidol University, Thailand

Study Documents (Full-Text)

None provided.

More Information

Publications

• Aslani FS, Dastgheib L, Banihashemi BM. Hair counts in scalp biopsy of males and females with androgenetic alopecia compared with normal subjects. J Cutan Pathol. 2009 Jul;36(7):734-9. doi: 10.1111/j.1600-0560.2008.01149.x.
• Elston DM, Ferringer T, Dalton S, Fillman E, Tyler W. A comparison of vertical versus transverse sections in the evaluation of alopecia biopsy specimens. J Am Acad Dermatol. 2005 Aug;53(2):267-72.
• Elston DM, McCollough ML, Angeloni VL. Vertical and transverse sections of alopecia biopsy specimens: combining the two to maximize diagnostic yield. J Am Acad Dermatol. 1995 Mar;32(3):454-7.
• Elston DM. Vertical vs. transverse sections: both are valuable in the evaluation of alopecia. Am J Dermatopathol. 2005 Aug;27(4):353-6. Review.
• Garcia C, Poletti E. Scalp biopsy specimens: transverse vs vertical sections. Arch Dermatol. 2007 Feb;143(2):268.
• Lee HJ, Ha SJ, Lee JH, Kim JW, Kim HO, Whiting DA. Hair counts from scalp biopsy specimens in Asians. J Am Acad Dermatol. 2002 Feb;46(2):218-21.
• Sperling LC. Hair density in African Americans. Arch Dermatol. 1999 Jun;135(6):656-8.

• Responsible Party: Rattapon Thuangtong, Assistant Professor, Siriraj Hospital
• ClinicalTrials.gov Identifier: NCT01651689
• Other Study ID Numbers: SirirajH-003; 553/2553(EC3)
• First Posted: Jul 27, 2012
• Last Update Posted: Jul 27, 2012
• Last Verified: Jul 1, 2012

• Keywords provided by Rattapon Thuangtong, Assistant Professor, Siriraj Hospital: Scalp biopsy; Hair count; Vertical section; Horizontal section; Thais
• Additional relevant MeSH terms: Alopecia; Alopecia Areata

Study Results

No Results Posted as of Jul 27, 2012