Magnesium Citrate Supplementation on Hand Grip Strength

Sponsor

Loma Linda University (Other)

Overall Status

Not yet recruiting

CT.gov ID

NCT06091007

Collaborator

(none)

154

Enrollment

Arms

Anticipated Duration (Months)

Study Details

Study Description

Brief Summary

The purpose of this research study is to determine the effectiveness of magnesium on handgrip strength using the more bioavailable magnesium citrate.

Condition or Disease	Intervention/Treatment	Phase
Hand Grasp	Dietary Supplement: Magnesium	N/A

Detailed Description

In this single-blind, randomized trial, participants will take a daily dose of either 200 or 400 milligrams of magnesium citrate supplement for four weeks, perform three separate handgrip strength tests using a dynamometer, complete a demographics questionnaire, a physical activity questionnaire, and a compliance log.

Study Design

Study Type:

Interventional

Anticipated Enrollment :

154 participants

Allocation:

Randomized

Intervention Model:

Parallel Assignment

Intervention Model Description:

Group 1: participants take 200 mg of magnesium citrate daily for 4 weeks. Group 2: participants take 400 mg of magnesium citrate daily for 4 weeks.Group 1: participants take 200 mg of magnesium citrate daily for 4 weeks. Group 2: participants take 400 mg of magnesium citrate daily for 4 weeks.

Masking:

None (Open Label)

Primary Purpose:

Other

Official Title:

The Effects of Magnesium Citrate Supplementation on Hand Grip Strength: A Randomized Control Trial

Anticipated Study Start Date :

Nov 1, 2023

Anticipated Primary Completion Date :

May 1, 2024

Anticipated Study Completion Date :

May 1, 2024

Arms and Interventions

Arm	Intervention/Treatment
Active Comparator: 200 mg Magnesium Participant will take 200 mg of magnesium citrate daily for 4 weeks	Dietary Supplement: Magnesium Magnesium citrate of either 200mg or 400 mg will be taken by the participant with food in the morning.
Active Comparator: 400 mg Magnesium Participant will take 400 mg of magnesium citrate daily for 4 weeks	Dietary Supplement: Magnesium Magnesium citrate of either 200mg or 400 mg will be taken by the participant with food in the morning.

Arm

Intervention/Treatment

Active Comparator: 200 mg Magnesium

Participant will take 200 mg of magnesium citrate daily for 4 weeks

Dietary Supplement: Magnesium

Magnesium citrate of either 200mg or 400 mg will be taken by the participant with food in the morning.

Active Comparator: 400 mg Magnesium

Participant will take 400 mg of magnesium citrate daily for 4 weeks

Dietary Supplement: Magnesium

Magnesium citrate of either 200mg or 400 mg will be taken by the participant with food in the morning.

Outcome Measures

Primary Outcome Measures

Hand grip strength [change between baseline and 4 weeks]
Participants will perform three separate handgrip strength tests using a Jamar Plus digital hand dynamometer, (Sammons Preston, Bolingbrook, Illinois). In each test, participants will do three trials resting for 15 seconds between trials, the average of the three trials will be recorded. To perform the hand grip strength test, the participant will hold the dynamometer in their dominant hand, with the arm at a right angle, and with the elbow by the side of the body. The participant then squeezes the hand dynamometer with maximum isometric effort for at least five seconds. Participants are required to not move any other part of the body and are encouraged to use maximum effort.

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Generally healthy community adults
Individuals age 18 and over
Male and female participants

Exclusion Criteria:

Individuals currently on magnesium supplements
Individuals currently on a multivitamin supplement
Individuals who currently suffer from hand pain or hand injury
Individuals who currently suffer from arthritis in their hands
Individuals suffering from a gastrointestinal disorder complicated by diarrhea, nausea, or abdominal cramping

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

Loma Linda University

Investigators

Principal Investigator: Kyndra Woosley, MS, Loma Linda University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Kyndra Woosley, Assistant Professor, Loma Linda University

ClinicalTrials.gov Identifier:

NCT06091007

Other Study ID Numbers:

5230401

First Posted:

Oct 19, 2023

Last Update Posted:

Oct 23, 2023

Last Verified:

Oct 1, 2023

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Keywords provided by Kyndra Woosley, Assistant Professor, Loma Linda University

hand grip magnesium citrate

Study Results

No Results Posted as of Oct 23, 2023