Three Techniques for Ultrasound Guided Axillary Brachial Plexus Block

Sponsor
Federal University of São Paulo (Other)
Overall Status
Unknown status
CT.gov ID
NCT02073383
Collaborator
(none)
313
1
3
19
16.5

Study Details

Study Description

Brief Summary

The brachial plexus block is an anesthetic technique often used for surgical procedures of the upper limb. The brachial plexus block through the axilla (BPVA) is one of the techniques most commonly used to obtain regional anesthesia of the upper limbs, being performed by anesthesia of the terminal branches of the brachial plexus, which would be the ulnar, median, radial and musculocutaneous nerves. With the aid of ultrasound , two techniques can be used to perform the BPVA . The first , known as multiple puncture technique , the local anesthetic is deposited around each nerve that want to block . This technique is most commonly used to perform the BPVA . The second technique , known as 2 injections , local anesthetic is deposited below the axillary artery and around the musculocutaneous nerve . This technique has been proposed to try to reduce the execution time of anesthesia . Studies actually show that the technique of 2 injections showed less time to perform the block, with the same success rate. However, the technique of 2 injections showed a longer latency and higher rate of vascular puncture . (14) In order to perform a procedure with shorter execution time , without changing the latency, success rate and ensuring patient safety , the investigators designed this protocol to evaluate three techniques for performing the ultrasound- guided axillary brachial plexus block.

Condition or Disease Intervention/Treatment Phase
  • Procedure: Axillary brachial plexus block
N/A

Study Design

Study Type:
Interventional
Anticipated Enrollment :
313 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Triple (Participant, Investigator, Outcomes Assessor)
Primary Purpose:
Treatment
Official Title:
Prospective Randomized Study of Three Different Techniques for Ultrasound Guided Axillary Brachial Plexus Block
Study Start Date :
Aug 1, 2013
Anticipated Primary Completion Date :
Dec 1, 2014
Anticipated Study Completion Date :
Mar 1, 2015

Arms and Interventions

Arm Intervention/Treatment
Experimental: Around Artery

Intervention Name: Axillary brachial plexus block Group A: 30 ml of 0.375% bupivacaine will be injected around the artery . If this were a clock, would deposit 7,5 ml of anesthetic in positions 0, 3, 6 and 9 .

Procedure: Axillary brachial plexus block

Experimental: Two injections

Group 2: 30 ml of bupivacaine 0.375 % below the artery will be injected in the 6 o'clock position .

Procedure: Axillary brachial plexus block

Active Comparator: Perineural

Group Perineural : 10 ml of bupivacaine 0.375 % will be injected around the median, ulnar and radial nerves .

Procedure: Axillary brachial plexus block

Outcome Measures

Primary Outcome Measures

  1. The primary outcome is to compare the efficacy of the three different techniques for ultrasound guided axillary brachial plexus block [The primary outcome will be measured at the same day of the procedure.]

    The brachial plexus block is performed through the axilla , with the aid of ultrasound and a peripheral nerve stimulator with the patient in the supine position. The needle that will be used is 22G x 50 mm . After disinfection and skin antisepsis with chlorhexidine , tha puncture site will be infiltrated with 1% lidocaine . Furthermore, musculocutaneous nerve will be blockade with 10 ml of 0.375% bupivacaine for all patients. Patients will be divided into three groups : Group A: 30 ml of 0.375% bupivacaine will be injected around the artery . If this were a clock, would deposit 7,5 ml of anesthetic in positions 0, 3, 6 and 9 . Group 2 injections : 30 ml of bupivacaine 0.375 % below the artery will be injected in the 6 o'clock position . Group M : 10 ml of bupivacaine 0.375 % will be injected

Secondary Outcome Measures

  1. Block Latency [30 minutes]

    Latency time of the blockade , defined as the time between the end of injection of local anesthetic will be noted.

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 65 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  • Informed consent signed by the patient (IC)

  • Indication for brachial plexus block for anesthesia and analgesia in candidates for hand surgical procedures

  • ASA physical status I, II or III according to the American Association of Anesthesiology.

Exclusion Criteria:
  • Cognitive impairment or psychiatric disease

  • Active infection condition at the puncture site of the block

  • Bleeding disorders

  • History of allergy to bupivacaine.

Contacts and Locations

Locations

Site City State Country Postal Code
1 Federal University of São Paulo São Paulo Sao Paulo Brazil 04024002

Sponsors and Collaborators

  • Federal University of São Paulo

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

Responsible Party:
Leonardo Henrique Cunha Ferraro, MD, Federal University of São Paulo
ClinicalTrials.gov Identifier:
NCT02073383
Other Study ID Numbers:
  • FUSaoPaulo - USG Guided Block
First Posted:
Feb 27, 2014
Last Update Posted:
Feb 27, 2014
Last Verified:
Feb 1, 2014
Keywords provided by Leonardo Henrique Cunha Ferraro, MD, Federal University of São Paulo

Study Results

No Results Posted as of Feb 27, 2014