Radiation Therapy in Treating Patients With Stage II Cancer of the Vocal Cord
Study Details
Study Description
Brief Summary
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known which radiation therapy regimen is more effective in treating patients with stage II cancer of the vocal cord.
PURPOSE: Randomized phase III trial to compare two regimens of radiation therapy in treating patients who have stage II cancer of the vocal cord.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
Phase 3 |
Detailed Description
OBJECTIVES:
-
Compare the local response rate in patients with stage II invasive squamous cell carcinoma of the true vocal cord treated with hyperfractionation vs conventional fractionation radiotherapy.
-
Compare the acute and late toxic effects of these regimens in this patient population.
-
Compare the overall and disease-free survival patterns in this patient population treated with these regimens.
OUTLINE: This is a randomized study. Patients are stratified according to substage (T2a vs T2b). Patients are randomized to 1 of 2 treatment arms.
-
Arm I: Patients undergo conventional radiotherapy 5 days a week for 5 weeks followed by boost radiotherapy 5 days a week for 2 weeks.
-
Arm II: Patients undergo hyperfractionation radiotherapy 5 days a week for 5 weeks followed by boost radiotherapy 5 days a week for 1.6 weeks.
Patients with biopsy-proven persistent disease at least 6 weeks after completion of radiotherapy undergo salvage surgery with neck dissection (at the discretion of the surgeon).
Patients are followed at 4 weeks, every 3 months for 1 year, every 4 months for 1 year, every 6 months for 3 years, and then annually thereafter.
PROJECTED ACCRUAL: A total of 240 patients will be accrued for this study within 3.2 years.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Active Comparator: Radiation therapy - conventional fractionation Radiation therapy - conventional fractionation (70 Gy/2 Gy once per day/7 Weeks) 35 fractions |
Radiation: radiation therapy
|
Experimental: Radiation therapy - hyperfractionation Radiation therapy - hyperfractionation (79.2 Gy/1.2 b.i.d/6.5 weeks) 66 fractions |
Radiation: radiation therapy
|
Outcome Measures
Primary Outcome Measures
- Local Control [From randomization to date of failure (local progression) or death or last follow-up. Analysis occurs after all patients have been potentially followed for 2 years.]
Secondary Outcome Measures
- Acute Toxicity [From start of treatment to 90 days]
- Late Toxicity [From 91 days after start of treatment to last follow-up.]
- Overall Survival [From randomization to date of death or last follow-up. Analysis occurs after all patients have been potentially followed for 2 years]
- Disease-free Survival [From randomization to date of failure (local, regional, or distant progression, second primary tumor, or death) or last follow-up. Analysis occurs after all patients have been potentially followed for 2 years.]
Eligibility Criteria
Criteria
DISEASE CHARACTERISTICS:
-
Histologically proven invasive squamous cell carcinoma of the true vocal cord
-
Stage II (T2a/b N0) disease with bulk of tumor present on vocal cord (i.e., the epicenter) with extension to adjacent areas
-
No verrucal carcinoma or adenocarcinoma
-
No extension to pre-epiglottic space or pyriform sinus
-
No fixed cord or cartilage invasion
-
No evidence of adenopathy, including any of the following:
-
Nodes larger than 1 cm by radiography
-
Nodes containing a low central density consistent with necrosis by radiography
-
Clinically palpable nodes larger than 1 cm and firm in consistency
-
No recurrent or persistent disease
-
No evidence or suspicion of distant metastases
PATIENT CHARACTERISTICS:
Age:
- 18 and over
Performance status:
- Karnofsky 60-100%
Life expectancy:
- Not specified
Hematopoietic:
- Not specified
Hepatic:
- Not specified
Renal:
- Not specified
Other:
-
No other malignancy within the past 5 years except nonmelanomatous skin cancer
-
Not pregnant or nursing
-
Fertile patients must use effective contraception
PRIOR CONCURRENT THERAPY:
Biologic therapy:
- Not specified
Chemotherapy:
- No prior chemotherapy
Endocrine therapy:
- Not specified
Radiotherapy:
- No prior radiotherapy to the mid-neck or larynx
Surgery:
- No prior complete stripping or laser excision of all gross disease
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | University of Alabama at Birmingham Comprehensive Cancer Center | Birmingham | Alabama | United States | 35294-3300 |
2 | Comprehensive Cancer Institute of Huntsville | Huntsville | Alabama | United States | 35801 |
3 | Huntsville Hospital System | Huntsville | Alabama | United States | 35807 |
4 | MBCCOP - Gulf Coast | Mobile | Alabama | United States | 36688 |
5 | Alabama Oncology, LLC | Montgomery | Alabama | United States | 36106-3657 |
6 | DCH Cancer Treatment Center | Tuscaloosa | Alabama | United States | 35401 |
7 | Foundation for Cancer Research and Education | Phoenix | Arizona | United States | 85013 |
8 | Mount Diablo Medical Center | Concord | California | United States | 94524-4110 |
9 | City of Hope Comprehensive Cancer Center | Duarte | California | United States | 91010-3000 |
10 | Saint Agnes Cancer Center | Fresno | California | United States | 93720 |
11 | California Cancer Center | Fresno | California | United States | 93729-5100 |
12 | Sutter Health West Cancer Research Group | Greenbrae | California | United States | 94904 |
13 | Loma Linda University Medical Center | Loma Linda | California | United States | 92354 |
14 | Veterans Affairs Medical Center - Long Beach | Long Beach | California | United States | 90822 |
15 | Jonsson Comprehensive Cancer Center, UCLA | Los Angeles | California | United States | 90025-1781 |
16 | USC/Norris Comprehensive Cancer Center and Hospital | Los Angeles | California | United States | 90033-0804 |
17 | CCOP - Bay Area Tumor Institute | Oakland | California | United States | 94609-3305 |
18 | Huntington Cancer Center | Pasadena | California | United States | 91105 |
19 | Robert and Beverly Lewis Family Cancer Care Center | Pomona | California | United States | 91767 |
20 | Radiation Oncology Center - Sacramento | Sacramento | California | United States | 95816 |
21 | Radiation Medical Group, Incorporated | San Diego | California | United States | 92101 |
22 | UCSF Comprehensive Cancer Center | San Francisco | California | United States | 94143-0128 |
23 | O'Connor Hospital | San Jose | California | United States | 95128 |
24 | CCOP - Santa Rosa Memorial Hospital | Santa Rosa | California | United States | 95403 |
25 | David Grant Medical Center | Travis Air Force Base | California | United States | 94535 |
26 | Memorial Hospital Cancer Center | Colorado Springs | Colorado | United States | 80909 |
27 | University of Colorado Cancer Center | Denver | Colorado | United States | 80010 |
28 | CCOP - Colorado Cancer Research Program, Incorporated | Denver | Colorado | United States | 80224 |
29 | Saint Mary's Hospital and Medical Center | Grand Junction | Colorado | United States | 81502-1628 |
30 | Hospital of St. Raphael | New Haven | Connecticut | United States | 06511 |
31 | CCOP - Christiana Care Health Services | Newark | Delaware | United States | 19713 |
32 | University of Florida Health Science Center | Gainesville | Florida | United States | 32610-0385 |
33 | Florida Radiation Oncology Group | Jacksonville | Florida | United States | 32207 |
34 | Holmes Regional Medical Center | Melbourne | Florida | United States | 32901-3276 |
35 | CCOP - Mount Sinai Medical Center | Miami Beach | Florida | United States | 33140 |
36 | Veterans Affairs Medical Center - Miami | Miami | Florida | United States | 33125 |
37 | Sylvester Cancer Center, University of Miami | Miami | Florida | United States | 33136 |
38 | Baptist Hospital of Miami | Miami | Florida | United States | 33256-2110 |
39 | MD Anderson Cancer Center Orlando | Orlando | Florida | United States | 32806-2134 |
40 | Bay Medical Center | Panama City | Florida | United States | 32401 |
41 | Gulf Coast Cancer Treatment Center | Panama City | Florida | United States | 32405-4587 |
42 | Sarasota Radiation and Medical Oncology Center | Sarasota | Florida | United States | 34233 |
43 | Tallahassee Memorial Healthcare | Tallahassee | Florida | United States | 32308 |
44 | H. Lee Moffitt Cancer Center and Research Institute | Tampa | Florida | United States | 33612-9497 |
45 | Emory University Hospital - Atlanta | Atlanta | Georgia | United States | 30322 |
46 | CCOP - Atlanta Regional | Atlanta | Georgia | United States | 30342-1701 |
47 | Medical Center/John B. Amos Community Cancer Center | Columbus | Georgia | United States | 31901 |
48 | Regional Radiation Oncology Center at Rome | Rome | Georgia | United States | 30165 |
49 | MBCCOP - Hawaii | Honolulu | Hawaii | United States | 96813 |
50 | Northwest Community Hospital | Arlington Heights | Illinois | United States | 60005 |
51 | Northwestern Memorial Hospital | Chicago | Illinois | United States | 60611 |
52 | CCOP - Central Illinois | Decatur | Illinois | United States | 62526 |
53 | Ingalls Memorial Hospital | Harvey | Illinois | United States | 60426 |
54 | Loyola University Medical Center | Maywood | Illinois | United States | 60153 |
55 | Lutheran General Cancer Care Center | Park Ridge | Illinois | United States | 60068 |
56 | Methodist Medical Center of Illinois | Peoria | Illinois | United States | 61636 |
57 | St. John's Medical Center | Anderson | Indiana | United States | 46016 |
58 | Bloomington Hospital | Bloomington | Indiana | United States | 47402 |
59 | Veterans Affairs Medical Center - Indianapolis (Roudebush) | Indianapolis | Indiana | United States | 46202 |
60 | Clarian Health Partners Inc. | Indianapolis | Indiana | United States | 46206-1367 |
61 | Community Regional Cancer Care | Indianapolis | Indiana | United States | 46219 |
62 | Ball Memorial Hospital | Muncie | Indiana | United States | 47303-3499 |
63 | CCOP - Northern Indiana CR Consortium | South Bend | Indiana | United States | 46601 |
64 | Wendt Regional Cancer Center of Finley Hospital | Dubuque | Iowa | United States | 52001 |
65 | Central Baptist Hospital | Lexington | Kentucky | United States | 40503 |
66 | Albert B. Chandler Medical Center, University of Kentucky | Lexington | Kentucky | United States | 40536-0084 |
67 | James Graham Brown Cancer Center | Louisville | Kentucky | United States | 40202 |
68 | Louisville Radiation Oncology | Louisville | Kentucky | United States | 40215 |
69 | Merle M. Mahr Cancer Center | Madisonville | Kentucky | United States | 42431 |
70 | Mary Bird Perkins Cancer Center | Baton Rouge | Louisiana | United States | 70809 |
71 | Tulane University School of Medicine | New Orleans | Louisiana | United States | 70112-2699 |
72 | MBCCOP - LSU Health Sciences Center | New Orleans | Louisiana | United States | 70112 |
73 | CCOP - Ochsner | New Orleans | Louisiana | United States | 70121 |
74 | Maine Medical Center | Portland | Maine | United States | 04102 |
75 | Anne Arundel Oncology Center | Annapolis | Maryland | United States | 21401 |
76 | Marlene and Stewart Greenebaum Cancer Center, University of Maryland | Baltimore | Maryland | United States | 21201 |
77 | Greater Baltimore Medical Center and Cancer Center | Baltimore | Maryland | United States | 21204 |
78 | Harbor Hospital Center | Baltimore | Maryland | United States | 21215-1290 |
79 | Sinai Hospital of Baltimore | Baltimore | Maryland | United States | 21215 |
80 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Baltimore | Maryland | United States | 21231-2410 |
81 | Peninsula Regional Medical Center | Salisbury | Maryland | United States | 21801 |
82 | Dana-Farber Cancer Institute | Boston | Massachusetts | United States | 02115 |
83 | Cape Cod Hospital | Hyannis | Massachusetts | United States | 02601 |
84 | Veterans Affairs Medical Center - Boston (Jamaica Plain) | Jamaica Plain | Massachusetts | United States | 02130 |
85 | CCOP - Michigan Cancer Research Consortium | Ann Arbor | Michigan | United States | 48106 |
86 | University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | United States | 48109-0010 |
87 | Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | United States | 48201-1379 |
88 | Henry Ford Hospital | Detroit | Michigan | United States | 48202 |
89 | Hurley Medical Center | Flint | Michigan | United States | 48503 |
90 | McLaren Regional Cancer Center | Flint | Michigan | United States | 48532-3685 |
91 | CCOP - Kalamazoo | Kalamazoo | Michigan | United States | 49007-3731 |
92 | Marquette General Hospital | Marquette | Michigan | United States | 49855 |
93 | MidMichigan Medical Center - Midland | Midland | Michigan | United States | 48670 |
94 | CCOP - Beaumont | Royal Oak | Michigan | United States | 48073-6769 |
95 | William Beaumont Hospital | Royal Oak | Michigan | United States | 48073 |
96 | William Beaumont Hospital - Troy | Troy | Michigan | United States | 48098 |
97 | Mayo Clinic Cancer Center | Rochester | Minnesota | United States | 55905 |
98 | CCOP - Metro-Minnesota | Saint Louis Park | Minnesota | United States | 55416 |
99 | Ellis Fischel Cancer Center - Columbia | Columbia | Missouri | United States | 65203 |
100 | CCOP - Kansas City | Kansas City | Missouri | United States | 64131 |
101 | Mallinckrodt Institute of Radiology | Saint Louis | Missouri | United States | 63108 |
102 | St. Louis University Health Sciences Center | Saint Louis | Missouri | United States | 63110-0250 |
103 | Cancer Research for the Ozarks | Springfield | Missouri | United States | 65807 |
104 | CCOP - Cancer Research for the Ozarks | Springfield | Missouri | United States | 65807 |
105 | CCOP - Montana Cancer Consortium | Billings | Montana | United States | 59101 |
106 | CCOP - Missouri Valley Cancer Consortium | Omaha | Nebraska | United States | 68106 |
107 | Methodist Hospital Cancer Center - Omaha | Omaha | Nebraska | United States | 68114 |
108 | Nebraska Health System | Omaha | Nebraska | United States | 68198-7460 |
109 | CCOP - Southern Nevada Cancer Research Foundation | Las Vegas | Nevada | United States | 89106 |
110 | Norris Cotton Cancer Center | Lebanon | New Hampshire | United States | 03756-0002 |
111 | Elliot Regional Cancer Center | Manchester | New Hampshire | United States | 03103 |
112 | Veterans Affairs Medical Center - East Orange | East Orange | New Jersey | United States | 07019 |
113 | John F. Kennedy Medical Center | Edison | New Jersey | United States | 08818 |
114 | Trinitas Hospital - Jersey Street Campus | Elizabeth | New Jersey | United States | 07201 |
115 | Monmouth Medical Center | Long Branch | New Jersey | United States | 07740-6395 |
116 | South Jersey Regional Cancer Center | Millville | New Jersey | United States | 08332 |
117 | Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital | Mount Holly | New Jersey | United States | 08060 |
118 | Cancer Institute of New Jersey | New Brunswick | New Jersey | United States | 38103-2807 |
119 | Newark Beth Israel Medical Center | Newark | New Jersey | United States | 07112 |
120 | Atlantic City Medical Center | Pomona | New Jersey | United States | 08240 |
121 | Valley Hospital | Ridgewood | New Jersey | United States | 07450 |
122 | Community Medical Center | Toms River | New Jersey | United States | 08755 |
123 | St. Francis Medical Center | Trenton | New Jersey | United States | 08629 |
124 | Associated Radiologists, P.A. | Warren | New Jersey | United States | 07059 |
125 | Radiation Oncology Associates of Albuquerque | Albuquerque | New Mexico | United States | 87109 |
126 | Cancer Center of Albany Medical Center | Albany | New York | United States | 12208 |
127 | State University of New York Health Science Center at Brooklyn | Brooklyn | New York | United States | 11203 |
128 | New York Methodist Hospital | Brooklyn | New York | United States | 11215 |
129 | Roswell Park Cancer Institute | Buffalo | New York | United States | 14263-0001 |
130 | Finger Lakes Radiation Oncology Center | Clifton Springs | New York | United States | 14432 |
131 | CCOP - North Shore University Hospital | Manhasset | New York | United States | 11030 |
132 | Herbert Irving Comprehensive Cancer Center | New York | New York | United States | 10032 |
133 | Champlain Valley Physicians Hospital Medical Center | Plattsburgh | New York | United States | 12901 |
134 | Vassar Brothers Medical Center | Poughkeepsie | New York | United States | 12601 |
135 | James P. Wilmot Cancer Center | Rochester | New York | United States | 14642 |
136 | CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C. | Syracuse | New York | United States | 13217 |
137 | Riverhill Radiation Oncology | Yonkers | New York | United States | 10701 |
138 | Lineberger Comprehensive Cancer Center, UNC | Chapel Hill | North Carolina | United States | 27599-7295 |
139 | Northeast Medical Center | Concord | North Carolina | United States | 28025 |
140 | East Carolina University School of Medicine | Greenville | North Carolina | United States | 27858-4354 |
141 | CCOP - Southeast Cancer Control Consortium | Winston-Salem | North Carolina | United States | 27104-4241 |
142 | Comprehensive Cancer Center at Wake Forest University | Winston-Salem | North Carolina | United States | 27157-1082 |
143 | Trinity Cancer Care Center | Minot | North Dakota | United States | 58701 |
144 | Akron General Medical Center | Akron | Ohio | United States | 44302 |
145 | Akron City Hospital | Akron | Ohio | United States | 44304 |
146 | Christ Hospital | Cincinnati | Ohio | United States | 45219 |
147 | Barrett Cancer Center | Cincinnati | Ohio | United States | 45267-0502 |
148 | Ireland Cancer Center | Cleveland | Ohio | United States | 44106-5065 |
149 | University Hospitals of Cleveland | Cleveland | Ohio | United States | 44106 |
150 | Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | United States | 44195 |
151 | CCOP - Columbus | Columbus | Ohio | United States | 43206 |
152 | Arthur G. James Cancer Hospital - Ohio State University | Columbus | Ohio | United States | 43210-1240 |
153 | CCOP - Dayton | Dayton | Ohio | United States | 45429 |
154 | CCOP - Toledo Community Hospital | Toledo | Ohio | United States | 43623-3456 |
155 | St. Anthony Hospital | Oklahoma City | Oklahoma | United States | 73101 |
156 | University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | United States | 73104 |
157 | St. John Health System | Tulsa | Oklahoma | United States | 74104 |
158 | CCOP - Oklahoma | Tulsa | Oklahoma | United States | 74136 |
159 | CCOP - Columbia River Program | Portland | Oregon | United States | 97225 |
160 | Lehigh Valley Hospital | Allentown | Pennsylvania | United States | 18105 |
161 | St. Luke's Hospital Cancer Center | Bethlehem | Pennsylvania | United States | 18015 |
162 | Geisinger Medical Center | Danville | Pennsylvania | United States | 17822-2001 |
163 | Mercy Fitzgerald Hospital | Darby | Pennsylvania | United States | 19023 |
164 | Delaware County Memorial Hospital | Drexel Hill | Pennsylvania | United States | 19026 |
165 | Pocono Cancer Center | East Stroudsburg | Pennsylvania | United States | 18301 |
166 | Milton S. Hershey Medical Center | Hershey | Pennsylvania | United States | 17033-0850 |
167 | Abramson Cancer Center of the University of Pennsylvania | Philadelphia | Pennsylvania | United States | 19104-4283 |
168 | Veterans Affairs Medical Center - Philadelphia | Philadelphia | Pennsylvania | United States | 19104 |
169 | Kimmel Cancer Center of Thomas Jefferson University - Philadelphia | Philadelphia | Pennsylvania | United States | 19107-5541 |
170 | Fox Chase Cancer Center | Philadelphia | Pennsylvania | United States | 19111 |
171 | Albert Einstein Cancer Center | Philadelphia | Pennsylvania | United States | 19141-3098 |
172 | Mercy Hospital of Pittsburgh | Pittsburgh | Pennsylvania | United States | 15219 |
173 | Western Pennsylvania Hospital | Pittsburgh | Pennsylvania | United States | 15224 |
174 | University of Pittsburgh Cancer Institute | Pittsburgh | Pennsylvania | United States | 15236 |
175 | Reading Hospital and Medical Center | Reading | Pennsylvania | United States | 19612-6052 |
176 | Mercy Hospital Cancer Center - Scranton | Scranton | Pennsylvania | United States | 18501 |
177 | Wilkes Barre General Hospital | Wilkes-Barre | Pennsylvania | United States | 18764 |
178 | York Cancer Center | York | Pennsylvania | United States | 17403 |
179 | Roger Williams Medical Center/BUSM | Providence | Rhode Island | United States | 02908-4735 |
180 | CCOP - Greenville | Greenville | South Carolina | United States | 29615 |
181 | CCOP - Upstate Carolina | Spartanburg | South Carolina | United States | 29303 |
182 | Rapid City Regional Hospital | Rapid City | South Dakota | United States | 57709 |
183 | Jackson-Madison County General Hospital | Jackson | Tennessee | United States | 38301-3956 |
184 | University of Tennessee Cancer Institute | Memphis | Tennessee | United States | 38103 |
185 | Vanderbilt-Ingram Cancer Center | Nashville | Tennessee | United States | 37232-5671 |
186 | Harrington Cancer Center | Amarillo | Texas | United States | 79106 |
187 | University of Texas Medical Branch | Galveston | Texas | United States | 77555-0209 |
188 | University of Texas - MD Anderson Cancer Center | Houston | Texas | United States | 77030-4009 |
189 | Wilford Hall Medical Center | Lackland Air Force Base | Texas | United States | 78236-5300 |
190 | Joe Arrington Cancer Research and Treatment Center | Lubbock | Texas | United States | 79410-1894 |
191 | Bayshore Medical Center | Pasadena | Texas | United States | 77504 |
192 | Dixie Regional Medical Center | Saint George | Utah | United States | 84770 |
193 | University of Utah Health Sciences Center | Salt Lake City | Utah | United States | 84132 |
194 | Latter Day Saints Hospital | Salt Lake City | Utah | United States | 84143 |
195 | Green Mountain Oncology Group | Burlington | Vermont | United States | 05401 |
196 | Vermont Cancer Center | Burlington | Vermont | United States | 05405-0075 |
197 | Cancer Center at the University of Virginia | Charlottesville | Virginia | United States | 22908 |
198 | RMH Regional Cancer Center | Harrisonburg | Virginia | United States | 22801 |
199 | Naval Medical Center, Portsmouth | Portsmouth | Virginia | United States | 23708-2197 |
200 | Bon Secours - St. Mary's Hospital | Richmond | Virginia | United States | 23226 |
201 | Massey Cancer Center | Richmond | Virginia | United States | 23298-0058 |
202 | Virginia Mason Medical Center | Seattle | Washington | United States | 98111 |
203 | Deaconess Medical Center | Spokane | Washington | United States | 99204 |
204 | Yakima Valley Memorial Hospital | Yakima | Washington | United States | 98902 |
205 | Schiffler Cancer Center | Wheeling | West Virginia | United States | 26003 |
206 | CCOP - St. Vincent Hospital Cancer Center, Green Bay | Green Bay | Wisconsin | United States | 54301 |
207 | St. Vincent Hospital | Green Bay | Wisconsin | United States | 54307-3508 |
208 | Gundersen Lutheran Medical Foundation | La Crosse | Wisconsin | United States | 54601 |
209 | Southern Wisconsin Radiotherapy Center | Madison | Wisconsin | United States | 53713 |
210 | University of Wisconsin Comprehensive Cancer Center | Madison | Wisconsin | United States | 53792 |
211 | Marshfield Clinic | Marshfield | Wisconsin | United States | 54449 |
212 | Community Memorial Hospital | Menomonee Falls | Wisconsin | United States | 53051 |
213 | Columbia Hospital | Milwaukee | Wisconsin | United States | 53211 |
214 | St. Luke's Medical Center | Milwaukee | Wisconsin | United States | 53215 |
215 | Medical College of Wisconsin Cancer Center | Milwaukee | Wisconsin | United States | 53226 |
216 | Veterans Affairs Medical Center - Milwaukee (Zablocki) | Milwaukee | Wisconsin | United States | 53295 |
217 | All Saints Cancer Center | Racine | Wisconsin | United States | 53405 |
218 | Waukesha Memorial Hospital Regional Cancer Center | Waukesha | Wisconsin | United States | 53188 |
219 | Tom Baker Cancer Center - Calgary | Calgary | Alberta | Canada | T2N 4N2 |
220 | Cross Cancer Institute | Edmonton | Alberta | Canada | T6G 1Z2 |
221 | Saint John Regional Hospital | Saint John | New Brunswick | Canada | E2L 4L2 |
222 | Newfoundland Cancer Treatment and Research Foundation | St. Johns | Newfoundland and Labrador | Canada | A1B 3V6 |
223 | Nova Scotia Cancer Centre | Halifax | Nova Scotia | Canada | B3H 1V7 |
224 | Cancer Care Ontario-Hamilton Regional Cancer Centre | Hamilton | Ontario | Canada | L8V 5C2 |
225 | Kingston Regional Cancer Centre | Kingston | Ontario | Canada | K7L 5P9 |
226 | Cancer Care Ontario-London Regional Cancer Centre | London | Ontario | Canada | N6A 4L6 |
227 | Ottawa Regional Cancer Centre | Ottawa | Ontario | Canada | K1H 1C4 |
228 | Northeastern Ontario Regional Cancer Centre, Sudbury | Sudbury | Ontario | Canada | P3E 5J1 |
229 | Northwestern Ontario Regional Cancer Centre, Thunder Bay | Thunder Bay | Ontario | Canada | P7A 7T1 |
230 | Toronto Sunnybrook Regional Cancer Centre | Toronto | Ontario | Canada | M4N 3M5 |
231 | Princess Margaret Hospital | Toronto | Ontario | Canada | M5G 2M9 |
232 | CHUS-Hopital Fleurimont | Fleurimont | Quebec | Canada | J1H 5N4 |
233 | Centre Hospitalier de l'Universite de Montreal | Montreal | Quebec | Canada | H2L 4MI |
234 | McGill University | Montreal | Quebec | Canada | H2W 1S6 |
235 | Centre Hospitalier Universitaire de Quebec | Quebec City | Quebec | Canada | G1R 2J6 |
236 | Allan Blair Cancer Centre | Regina | Saskatchewan | Canada | S4T 7T1 |
237 | Saskatoon Cancer Centre | Saskatoon | Saskatchewan | Canada | S7N 4H4 |
Sponsors and Collaborators
- Radiation Therapy Oncology Group
- National Cancer Institute (NCI)
Investigators
- Study Chair: Andy M. Trotti, MD, H. Lee Moffitt Cancer Center and Research Institute
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- RTOG-9512
- CDR0000064597