Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients

Sponsor
University Hospital Muenster (Other)
Overall Status
Unknown status
CT.gov ID
NCT00132223
Collaborator
(none)
10
1
8
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Study Details

Study Description

Brief Summary

Angiographies of the supra-aortic vessels by magnetic imaging have become common recently. So it was the purpose of this study to evaluate the imaging potential of different contrast agents.

Three contrast agents for magnetic resonance imaging are compared in angiographies of the supra-aortic arteries in a intraindividual study of 10 patients.

All applications of these contrast agents are performed with a flow of 2 ml/s. One contrast medium is applicated a second time with a reduced flow of 1 ml/s.

The angiographies of the supra-aortic vessels are evaluated by two experienced readers in a consensus reading. The signal/noise- and contrast/noise-ratio of anatomic vessel segments of the carotic and vertebral arteries are measured and compared to each other.

Condition or Disease Intervention/Treatment Phase
  • Drug: Contrast agent
Phase 4

Study Design

Study Type:
Interventional
Allocation:
Non-Randomized
Intervention Model:
Single Group Assignment
Masking:
Single
Primary Purpose:
Diagnostic
Official Title:
Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients With Headache and Dizziness or Epilepsy and Clinical Indication for an Angiography by Magnetic Imaging
Study Start Date :
Apr 1, 2005
Study Completion Date :
Dec 1, 2005

Outcome Measures

Primary Outcome Measures

  1. intensity of vessels, muscle, air []

Secondary Outcome Measures

  1. signal/noise ratio []

  2. contrast/nose ratio []

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 60 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  • Headache

  • Epilepsia

  • Dizziness

Exclusion Criteria:
  • Pregnancy

  • Metal implants (e.g. pacemaker)

  • Contraindication for contrast agent

  • Multiple allergies

Contacts and Locations

Locations

Site City State Country Postal Code
1 University of Muenster, Dept. of Clinical Radiology Muenster Germany 48129

Sponsors and Collaborators

  • University Hospital Muenster

Investigators

  • Study Chair: Bernd Tombach, MD, University of Muenster, Dept. of Clinical Radiology

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
, ,
ClinicalTrials.gov Identifier:
NCT00132223
Other Study ID Numbers:
  • 0710/2004-IKR
First Posted:
Aug 19, 2005
Last Update Posted:
Apr 12, 2006
Last Verified:
Apr 1, 2006

Study Results

No Results Posted as of Apr 12, 2006