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Neuro-cognitive Bases of Joint Action

Sponsor
Istituto Ortopedico Galeazzi (Other)
Overall Status
Unknown status
CT.gov ID
NCT03369860
Collaborator
(none)
50
Enrollment
1
Location
1
Arm
32.6
Anticipated Duration (Months)
1.5
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The ability to interact with conspecifics is crucial in life, yet there is no consensus on the underlying cognitive and neural mechanisms beyond those associated with imitative behaviors. This project aims to define a coherent model of non-imitative (complementary) motor interactions. The investigators hypothesize that these might be substantially based on the ability to integrate one's own and a partner's action within a unitary, dual- person (dyadic), motor plan that incorporates a shared goal.

With a novel "minimally-joint" paradigm the investigators will test this hypothesis and measure with behavioral measures (i.e., reaction times) whether the supposedly automatic tendency to imitate others is modulated by the need to coordinate with a partner to achieve a shared goal.

This paradigm will be also applied during a functional MRI experiment to describe the underlying neurophysiological patterns; using dynamic causal modeling the investigators will measure how the brain regions relevant for dyadic motor control are functionally linked.

This converging experimental strategy will permit to compare competing psychological and neural models of motor interactions in healthy participants, opening new experimental avenues for studies in adult neuropsychological patients and in children with typical and atypical social development.

Condition or Disease Intervention/Treatment Phase
  • Behavioral: Interactivity of Experimental Condition
 N/A

Study Design

Study Type:
Interventional
Anticipated Enrollment :
50 participants
Allocation:
N/A
Intervention Model:
Single Group Assignment
Masking:
None (Open Label)
Primary Purpose:
Basic Science
Official Title:
Basi Neuro-cognitive Dell'Interazione Motoria
Actual Study Start Date :
Apr 1, 2017
Anticipated Primary Completion Date :
Dec 20, 2018
Anticipated Study Completion Date :
Dec 20, 2019

Arms and Interventions

Arm Intervention/Treatment
Experimental: Healthy Subjects

Healthy Subjects take part in the experimental manipulation

Behavioral: Interactivity of Experimental Condition
The neurofunctional correlates of motor control will be compared between a collaborative and non-interactive condition.

Outcome Measures

Primary Outcome Measures

  1. Reaction Times [1 year]

    The investigators will compare Reaction Times of participants recorded during Joint Action with those recorded in Non-Joint individual condition.

  2. BOLD activations [1 year]

    The investigators will study the neurofunctional activations indexed by the Blood Oxygen Level Dependent (BOLD) recorded during Joint Action will be compared to the Non-Joint actions

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 35 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • right handed; no contraindication to MRI
Exclusion Criteria:
  • contraindication to MRI

Contacts and Locations

Locations

Site City State Country Postal Code
1 IRCCS Galeazzi Orthopedic Hospital Milan Italy 20161

Sponsors and Collaborators

  • Istituto Ortopedico Galeazzi

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Istituto Ortopedico Galeazzi
ClinicalTrials.gov Identifier:
NCT03369860
Other Study ID Numbers:
  • JOINT
First Posted:
Dec 12, 2017
Last Update Posted:
Aug 10, 2018
Last Verified:
Aug 1, 2018
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No

Study Results

No Results Posted as of Aug 10, 2018