SWAP-MEAT Athlete: Three Diets on Athletic Performance

Sponsor
Stanford University (Other)
Overall Status
Completed
CT.gov ID
NCT05472701
Collaborator
(none)
24
1
3
5.3
4.6

Study Details

Study Description

Brief Summary

This study aims to investigate the impact of two plant-based diets-whole food plant-based (WFPB) and plant-based meat alternatives (PBMA)-vs. an omnivorous diet (Animal) on endurance and muscular strength in recreational athletes.

Condition or Disease Intervention/Treatment Phase
  • Behavioral: Diet order: WFPB, PBMA, Animal
  • Behavioral: WFPB, Animal, PBMA
  • Behavioral: PBMA, WFPB, Animal
  • Behavioral: PBMA, Animal, WFPB
  • Behavioral: Animal, WFPB, PBMA
  • Behavioral: Animal, PBMA, WFPB
N/A

Detailed Description

Plant-based diets are environmentally sustainable and beneficial for cardiovascular health, but athletes are often concerned that these diets do not contain enough protein to support athletic performance. However, few randomized trials investigating the effect of plant-based vs. omnivorous diets on athletic performance have been conducted. Within this randomized crossover trial, recreational runners and resistance trainers will be assigned to three diets for four weeks each (WFPB, PBMA, and Animal). PMBA is an emerging, modern type of plant-based diet for which the impact on athletic performance has not yet been assessed. Participants will complete athletic fields at baseline and after each diet, and athletic performance on diets and study feasibility in this cohort of recreational athletes will be assessed. The study design was inspired by the original SWAP-MEAT study that investigated cardiovascular risk factors in adults consuming 8-week omnivorous and plant-based meat alternative diets (Crimarco, 2020).

Study Design

Study Type:
Interventional
Actual Enrollment :
24 participants
Allocation:
Randomized
Intervention Model:
Crossover Assignment
Intervention Model Description:
SWAP-MEAT Athlete is a randomized crossover trial in which 12 recreational runners and 12 recreational resistance trainers are assigned to one of six possible diet orders. Each diet order contains three phases for four weeks each-Animal, Plant-Based Meat Alternatives (PBMA), and Whole Food Plant-Based (WFPB)-in random order.SWAP-MEAT Athlete is a randomized crossover trial in which 12 recreational runners and 12 recreational resistance trainers are assigned to one of six possible diet orders. Each diet order contains three phases for four weeks each-Animal, Plant-Based Meat Alternatives (PBMA), and Whole Food Plant-Based (WFPB)-in random order.
Masking:
Single (Outcomes Assessor)
Primary Purpose:
Other
Official Title:
SWAP-MEAT (Study With Appetizing Plant-Food, Meat Eating Alternatives Trial) Athlete
Actual Study Start Date :
Apr 26, 2021
Actual Primary Completion Date :
Oct 3, 2021
Actual Study Completion Date :
Oct 3, 2021

Arms and Interventions

Arm Intervention/Treatment
Experimental: Whole Food Plant-Based (WFPB)

2 meals/day of traditional plant proteins (tofu, quinoa, black beans) and minimized intake of processed food, eggs, and dairy

Behavioral: Diet order: WFPB, PBMA, Animal
Participants followed the WFPB, PBMA, and Animal diets (in this order) for 4 weeks each.

Behavioral: WFPB, Animal, PBMA
Participants followed the WFPB, Animal, and PBMA diets (in this order) for 4 weeks each.

Behavioral: PBMA, WFPB, Animal
Participants followed the PBMA, WFPB, and Animal diets (in this order) for 4 weeks each.

Behavioral: PBMA, Animal, WFPB
Participants followed the PBMA, Animal, and WFPB diets (in this order) for 4 weeks each.

Behavioral: Animal, WFPB, PBMA
Participants followed the Animal, WFPB, and PBMA diets (in this order) for 4 weeks each.

Behavioral: Animal, PBMA, WFPB
Participants followed the Animal, PBMA, and WFPB diets (in this order) for 4 weeks each.

Experimental: Plant-Based Meat Alternatives (PBMA)

2 servings/day of plant-based meat alternatives (Beyond Beef, Impossible Burger, Gardein Chick'n)

Behavioral: Diet order: WFPB, PBMA, Animal
Participants followed the WFPB, PBMA, and Animal diets (in this order) for 4 weeks each.

Behavioral: WFPB, Animal, PBMA
Participants followed the WFPB, Animal, and PBMA diets (in this order) for 4 weeks each.

Behavioral: PBMA, WFPB, Animal
Participants followed the PBMA, WFPB, and Animal diets (in this order) for 4 weeks each.

Behavioral: PBMA, Animal, WFPB
Participants followed the PBMA, Animal, and WFPB diets (in this order) for 4 weeks each.

Behavioral: Animal, WFPB, PBMA
Participants followed the Animal, WFPB, and PBMA diets (in this order) for 4 weeks each.

Behavioral: Animal, PBMA, WFPB
Participants followed the Animal, PBMA, and WFPB diets (in this order) for 4 weeks each.

Experimental: Animal

2 servings/day of traditional meat products (beef burger, pork, chicken)

Behavioral: Diet order: WFPB, PBMA, Animal
Participants followed the WFPB, PBMA, and Animal diets (in this order) for 4 weeks each.

Behavioral: WFPB, Animal, PBMA
Participants followed the WFPB, Animal, and PBMA diets (in this order) for 4 weeks each.

Behavioral: PBMA, WFPB, Animal
Participants followed the PBMA, WFPB, and Animal diets (in this order) for 4 weeks each.

Behavioral: PBMA, Animal, WFPB
Participants followed the PBMA, Animal, and WFPB diets (in this order) for 4 weeks each.

Behavioral: Animal, WFPB, PBMA
Participants followed the Animal, WFPB, and PBMA diets (in this order) for 4 weeks each.

Behavioral: Animal, PBMA, WFPB
Participants followed the Animal, PBMA, and WFPB diets (in this order) for 4 weeks each.

Outcome Measures

Primary Outcome Measures

  1. Cooper 12-Minute Timed Run Test (Runners) [Baseline, Week 4, Week 8, Week 12]

    Change from baseline in distance covered on a 12-minute timed run after each diet phase

  2. Composite Machine Strength Index (Resistance Trainers) [Baseline, Week 4, Week 8, Week 12]

    Change from baseline in composite machine strength index (sum of 3-rep max chest press, leg press, and lat pull-down) after each diet phase

Secondary Outcome Measures

  1. Estimated VO2 max (Runners) [Baseline, Week 4, Week 8, Week 12]

    Change in VO2 max, estimated from training data compiled by Garmin Forerunner 235 after each diet phase

  2. Maximum push-up and pull-up test [Baseline, Week 4, Week 8, Week 12]

    Change from baseline in maximum number of repetitions completed of push-up and pull-ups prior to exhaustion after each diet phase

  3. Dietary intake and adherence [Baseline, Week 4, Week 8, Week 12]

    a. Nutrient composition of each diet and adherence to diet in servings of protein source consumed per week, via weekly dietary logs

  4. Diet satisfaction [Week 4, Week 8, Week 12]

    Score on Food Acceptability Questionnaire, measuring taste, appeal, and overall diet satisfaction, after each diet. We used the "Food Acceptability Questionnaire", with a minimum value of 1 and a maximum value of 7. A higher score indicates better food acceptability.

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 35 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • Generally healthy omnivorous adults between 18 and 35 years of age who report typically consuming at least 1 serving of meat per day and are willing to consume ~2 servings per day of animal meat, plant-based meat alternatives, and whole-food plant proteins.

  • Participants will have been consistent recreational runners or weightlifters (3-4 times per week) for at least the prior 1 year, and currently run or lift 3-4 times per week.

  • Runners will engage in at least 150 minutes of moderate-to-vigorous aerobic activity or 75 minutes of vigorous activity per week. All participants will have habitually consumed an omnivorous diet for at least months.

  • Participants will have self-reported good health and BMI 18.5-30.0.

  • Participants must be able to commit to running or resistance training at least 3-4 times per week for the 12 week duration of the study.

Exclusion Criteria:
  • Individuals who have participated in any restrictive diet within the last month, have any known nutrient intolerances, have orthopedic limitations, are participating in any other physical activity or diet study;

  • Individuals consuming any performance enhancing drugs or medications known to interfere with athletic performance;

  • Individuals who have a chronic disease or eating disorder, are currently pregnant or intend to become pregnant in the next three months, or have an intent to compete in any physical activity competition within the next 3 months.

Contacts and Locations

Locations

Site City State Country Postal Code
1 Stanford University Stanford California United States 94305

Sponsors and Collaborators

  • Stanford University

Investigators

  • Principal Investigator: Christopher D Garnder, PhD, Stanford University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Christopher Gardner, Principal Investigator, Stanford University
ClinicalTrials.gov Identifier:
NCT05472701
Other Study ID Numbers:
  • 59905
First Posted:
Jul 25, 2022
Last Update Posted:
Aug 1, 2022
Last Verified:
Jul 1, 2022
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Christopher Gardner, Principal Investigator, Stanford University

Study Results

No Results Posted as of Aug 1, 2022