Health Status of < 50 Year Old Patients After Surgically Implanted Biological and Mechanical Aortic Valves: a Population-based Retrospective Analysis (2010-2020)
Study Details
Study Description
Brief Summary
The overall project aim is to study outcomes following aortic valve replacement with either mechanical valves or bioprostheses by retrieving data from the main social security carriers in Austria for the years 2010-2020 in under 50 year old patients.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
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Detailed Description
The purpose of this research project is to evaluate mortality (primary outcome) and incidence of heart attack, stroke, reoperation and first diagnosis of heart insufficiency, MACE (secondary outcomes) after aortic valve replacement in under 50 year olds. We aim to compare those outcomes between mechanical valves and bioprostheses.
Data will be retrieved from the main social security carriers in Austria (covering 98% of its population) from 2010-2020.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Aortic valve replacement with mechanical valves
|
Device: Aortic Valve Replacement
Surgical replacement of aortic valves
|
Aortic valve replacement with bioprostheses
|
Device: Aortic Valve Replacement
Surgical replacement of aortic valves
|
Outcome Measures
Primary Outcome Measures
- Overall mortality [10 years]
all cause mortality after aortic valve replacement
Secondary Outcome Measures
- reoperation [10 years]
incidence of reoperation after aortic valve replacement
- stroke [10 years]
incidence of stroke after aortic valve replacement
- heart attack [10 years]
incidence of heart attack after aortic valve replacement
- heart insufficiency [10 years]
incidence of heart insufficiency after aortic valve replacement
- MACE [10 years]
incidence of MACE after aortic valve replacement
Eligibility Criteria
Criteria
Inclusion Criteria:
- isolated surgical aortic valve replacement in Austria
Exclusion Criteria:
-
below 18 years of age
-
above 50 years of age
-
concomitant heart surgery
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Medical University of Vienna
- Sicknessfund Burgenland
- Landesklinikum Sankt Polten
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- AUTHEARTVISIT < 50