Clincosm LogoSign in Get a demo

CHO: Influencing Factors on Training Efficacy in Healthy Adults

Sponsor
Universität des Saarlandes (Other)
Overall Status
Completed
CT.gov ID
NCT02297646
Collaborator
(none)
23
Enrollment
1
Location
2
Arms
16
Duration (Months)
1.4
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The purpose of this study is to investigate the effects of carbohydrate intake on training efficacy and health parameters of an endurance training program in healthy adults.

Condition or Disease Intervention/Treatment Phase
  • Behavioral: Endurance Training
 Early Phase 1

Detailed Description

Carbohydrate availability in endurance exercise seems to attenuate exercise-induced perturbations of cellular homeostasis and consequently diminishes the stimulus for training adaptation. Therefore, a negative relationship with exercise efficacy seems plausible. However, experimental evidence is rare and far from conclusive. Therefore, the present study aims to test the influence of carbohydrate intake on the efficacy of a typical preventive training program.

Study Design

Study Type:
Interventional
Actual Enrollment :
23 participants
Allocation:
Randomized
Intervention Model:
Crossover Assignment
Masking:
None (Open Label)
Primary Purpose:
Prevention
Official Title:
The Influence of Carbohydrates on Training Efficacy and Health Status in Healthy Adults
Study Start Date :
Aug 1, 2012
Actual Primary Completion Date :
Dec 1, 2013
Actual Study Completion Date :
Dec 1, 2013

Arms and Interventions

Arm Intervention/Treatment
Experimental: Carbohydrates

50 grams of carbohydrates 4 times a week for each training session

Behavioral: Endurance Training
Other Names:
  • 4 sessions a week at 70 percent heart rate reserve

    		•
    Placebo Comparator: Control

    no carbohydrate intake

    Behavioral: Endurance Training
    Other Names:
  • 4 sessions a week at 70 percent heart rate reserve

    		•

    Outcome Measures

    Primary Outcome Measures

    1. Maximum oxygen consumption (VO2max) [24 weeks]

      VO2max

    Secondary Outcome Measures

    1. Numerous serum parameters from venous blood (LDL, HDL, Cholesterol, Triglycerides) [24 weeks]

      cardiovascular parameters: LDL HDL Cholesterol Triglycerides

    2. Resting heart rate [24 weeks]

    3. Resting blood pressure [24 weeks]

    4. Body fat (Skinfold thickness) [24 weeks]

      Skinfold thickness

    5. Ventilatory anaerobic threshold (VT) [24 weeks]

      VT

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    30 Years to 65 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:

    • no diseases

    • nonsmoker

    • BMI 25-30 kg/m²

    • blood pressure <160/100 mm/Hg

    • unmedicated

    • untrained status

    • V̇O2max < 50 mL/kg/min

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Institute of Sports and Preventive Medicine, Saarland University Saarbrücken Saarland Germany 66012

    Sponsors and Collaborators

    • Universität des Saarlandes

    Investigators

    • Principal Investigator: Tim Meyer, M.D. Prof., Universität des Saarlandes

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Anne Krieg M.D., M.D., Universität des Saarlandes
    ClinicalTrials.gov Identifier:
    NCT02297646
    Other Study ID Numbers:
    • Saarland University - CHO
    First Posted:
    Nov 21, 2014
    Last Update Posted:
    Nov 21, 2014
    Last Verified:
    Nov 1, 2014
    Keywords provided by Anne Krieg M.D., M.D., Universität des Saarlandes
    Prevention
    Exercise
    Health
    Endurance

    Study Results

    No Results Posted as of Nov 21, 2014