COVIACS: Healthcare-associated Infections in Severe COVID-19 During 2020

Sponsor
Sanatorio Anchorena San Martin (Other)
Overall Status
Completed
CT.gov ID
NCT04819165
Collaborator
(none)
252
1
11
22.8

Study Details

Study Description

Brief Summary

In patients who develop ARDS due to SARS-CoV-2 (CARDS), a longer duration of invasive mechanical ventilation (IMV) and ICU stay has been reported compared to ARDS not associated with SARS-CoV-2. Consequently, the days of stay in ICU increase Identifying the risk factors associated with the development of this complication and developing measures aimed at its prevention could have a favorable impact on the clinical course of seriously ill patients.

Condition or Disease Intervention/Treatment Phase
  • Other: COVID-19

Detailed Description

The rate of catheter-associated bacteremia is 3.78 / 1000 days central venous catheters in polyvalent ICUs.

Some studies suggest that in the context of this pandemic, infections associated with health care have increased, although there are few data referring to Latin America.

The objective of this study is to analyze the incidence of health care associated infections in adult patients on invasive mechanical ventilation with confirmed COVID-19 diagnosis and negative COVID-19 admitted to the Intensive Care Unit of the Anchorena San Martín Clinic, San Martín, Buenos Aires.

Study Design

Study Type:
Observational
Actual Enrollment :
252 participants
Observational Model:
Cohort
Time Perspective:
Retrospective
Official Title:
Healthcare-associated Infections in Severe COVID-19 Patients Whit Mechanical Ventilation During 2020
Actual Study Start Date :
Mar 1, 2020
Actual Primary Completion Date :
Dec 31, 2020
Actual Study Completion Date :
Jan 31, 2021

Arms and Interventions

Arm Intervention/Treatment
COVID-19 patients

Patients with invasive mechanical ventilation admitted to the Intensive Care Unit (UCI) of the Anchorena San Martín Clinic, San Martín, Buenos Aires with confirmed COVID-19 diagnosis (positive polymerase chain reaction in nasopharyngeal swab).

Other: COVID-19
Impact of covid-19 on infections associated with health care devices.

non COVID-19 patients

Patients with invasive mechanical ventilation admitted to the Intensive Care Unit (UCI) of the Anchorena San Martín Clinic, San Martín, Buenos Aires with negative COVID-19 diagnosis (positive polymerase chain reaction in nasopharyngeal swab).

Outcome Measures

Primary Outcome Measures

  1. Incidence of health care associated infections in each group. [March to December 2020]

Secondary Outcome Measures

  1. The most frequent pathogens in this population associated with Incidence of health care associated infections. [March to December 2020]

  2. Possible factors associated with Incidence of health care associated infections. [March to December 2020]

  3. mortality in UCI [March to December 2020]

  4. Days of ICU stay [March to December 2020]

  5. Days of mechanical ventilation [March to December 2020]

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  • All patients older than 18 years admitted to the intensive care unit of the Anchorena San Martín Clinic who required invasive mechanical ventilation for more than 24 hours in a period between March 2020 and December 2020 were included in the analysis.
Exclusion Criteria:
  • All patients who presented incomplete data in the follow-up sheets were excluded.

Contacts and Locations

Locations

Site City State Country Postal Code
1 Sanatorio Anchorena de San Martin San Martín Buenos Aires Argentina B1650CQU

Sponsors and Collaborators

  • Sanatorio Anchorena San Martin

Investigators

  • Principal Investigator: matias accoce, SAnchorena San Martin

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Matias Accoce, RT, Sanatorio Anchorena San Martin
ClinicalTrials.gov Identifier:
NCT04819165
Other Study ID Numbers:
  • 5/2021
First Posted:
Mar 26, 2021
Last Update Posted:
Mar 26, 2021
Last Verified:
Mar 1, 2021
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of Mar 26, 2021