Spot Reduction in Male Adults

• Sponsor: Molde University College (Other)
• Overall Status: Completed
• CT.gov ID: NCT05794854
• Collaborator: Norwegian University of Science and Technology (Other)
• Enrollment: 16
• Arms: 2
• Actual Duration (Months): 9

Study Details

Study Description

Brief Summary

Spot reduction, referring to local body fat reduction, pertains to subcutaneous adipose tissue utilization from specific body parts during exercise. Its existence has been keenly debated, although generally accepted not to occur during exercise. However, it is based on not only equivocal data - commonly the training protocol typically applied is based on strength rather than endurance training. The investigators sought to test this assumption by utilizing endurance based exercise controlling for energy expenditure and using dual x-ray absorptiometric measures to assess body composition before and after training.

Condition or Disease	Intervention/Treatment	Phase
Healthy	Other: Abdominal aerobic endurance exercise; Other: Control training intervention	N/A

Study Design

• Study Type: Interventional
• Actual Enrollment: 16 participants
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Masking: Single (Outcomes Assessor)
• Masking Description: Assessor of dual x-ray absorptiometry results was blinded to group allocation
• Primary Purpose: Basic Science
• Official Title: The Assessment of Spot Reduction in Adults Males Following Endurance Training
• Actual Study Start Date: Aug 1, 2005
• Actual Primary Completion Date: May 1, 2006
• Actual Study Completion Date: May 1, 2006

Arms and Interventions

Arm	Intervention/Treatment
Experimental: abdominal aerobic endurance exercise Subjects were combining treadmill running at 70% HRmax (27 minutes) with 4x4minutes (30-40% maximal strength, 1RM) of torso rotation and abdominal crunches (57 minutes), 4 d per wk for 10 weeks	Other: Abdominal aerobic endurance exercise; Subjects combined treadmill running at 70% HRmax (27 minutes) with 4x4minutes (30-40% maximal strength, 1RM) of torso rotation and abdominal crunches (57 minutes), 4 days per wk for 10 weeks
Active Comparator: Control group Subjects performed only treadmill running (45 minutes) at 70% HRmax for 4 d per week for 10 weeks.	Other: Control training intervention; Subjects performed treadmill running (45 minutes) at 70% HRmax 4 days per week for 10 weeks

Outcome Measures

Primary Outcome Measures

1. Trunk fat mass change [Change from pre (baseline) to post test (after 10 weeks)]

   Fat mass located in trunk (g) measured by dual-energy x-ray absorptiometry

Secondary Outcome Measures

1. Lower extremity fat mass change [Change from pre (baseline) to post test (after 10 weeks)]

   Fat mass located in lower extremities (g) measured by dual-energy x-ray absorptiometry

2. Upper extremity fat mass change [Change from pre (baseline) to post test (after 10 weeks)]

   Fat mass located in upper extremities (g) measured by dual-energy x-ray absorptiometry

3. Total fat mass change [Change from pre (baseline) to post test (after 10 weeks)]

   Total fat mass (g) measured by dual-energy x-ray absorptiometry

4. Body weight change [Change from pre (baseline) to post test (after 10 weeks)]

5. Body mass index change [Change from pre (baseline) to post test (after 10 weeks)]

6. Waist circumference (cm) change [Change from pre (baseline) to post test (after 10 weeks)]

7. Hip circumference (cm) change [Change from pre (baseline) to post test (after 10 weeks)]

Other Outcome Measures

1. Trunk lean mass change [Change from pre (baseline) to post test (after 10 weeks)]

   Lean mass located in trunk (g) measured by dual-energy x-ray absorptiometry

2. Lower extremity lean mass change [Change from pre (baseline) to post test (after 10 weeks)]

   Lean mass located in lower extremities (g) measured by dual-energy x-ray absorptiometry

3. Upper extremity lean mass change [Change from pre (baseline) to post test (after 10 weeks)]

   Lean mass located in upper extremities (g) measured by dual-energy x-ray absorptiometry

4. Total lean mass change [Change from pre (baseline) to post test (after 10 weeks)]

   Total lean mass (g) measured by dual-energy x-ray absorptiometry

5. Maximal oxygen uptake change [Change from pre (baseline) to post test (after 10 weeks)]

   Maximal oxygen uptake by cardiopulmonary indirect calorimetry

6. Maximal muscle strength change [Change from pre (baseline) to post test (after 10 weeks)]

   One-repetition maximum (kg) in torso rotation and abdominal crunch

Eligibility Criteria

Criteria

• Ages Eligible for Study: 30 Years to 60 Years
• Sexes Eligible for Study: Male
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

• males

• ≥ 30 years old

• classified as overweight (Body mass index ≥ 25 kg ∙ m-2)

• not participating in regular physical training

Exclusion Criteria:

• < 30 years old

• Body mass index < 25 kg ∙ m-2

• participating in regular physical training

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

• Molde University College
• Norwegian University of Science and Technology

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Molde University College
• ClinicalTrials.gov Identifier: NCT05794854
• Other Study ID Numbers: MUCSR12
• First Posted: Apr 3, 2023
• Last Update Posted: Apr 3, 2023
• Last Verified: Mar 1, 2023

• Individual Participant Data (IPD) Sharing Statement: No
• Plan to Share IPD: No
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Keywords provided by Molde University College: endurance exercise; subcutaneous tissue utilization

Study Results

No Results Posted as of Apr 3, 2023