Acute Effects of Beetroot Juice on Isometric Knee Extension Strength, Explosive Strength and Local Muscular Endurance

Sponsor

University of Primorska (Other)

Overall Status

Completed

CT.gov ID

NCT05567926

Collaborator

(none)

Enrollment

Location

Arms

Actual Duration (Days)

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

This is a double-blind placebo-controlled cross-over trial that aims to determine the acute effect of beetroot juice ingestion on isometric knee extension strength, explosive strength and local muscular endurance.

Condition or Disease	Intervention/Treatment	Phase
Healthy Adults	Dietary Supplement: Beetroot juice concentrate (140 ml) Dietary Supplement: Blackcurrant juice (placebo)	N/A

Detailed Description

The study aims to determine whether concentrated beetroot juice has an acute effect on isometric strength of the knee muscles and the rate of force development in knee extension, as well as endurance of the same muscle. This will be a cross-over study. 20 subjects will be randomly selected to the experimental group or control group; after 1 week, participants will repeat the measurements in the other condition. Subjects will consume 140 ml of beetroot juice extract 2.5 hours before the measurement or placebo (140 ml of blackcurrant juice with added appropriate amount of sugar to equalize the carbohydrate value and lemon juice fort the taste). An isometric dynamometer will be used to measure the isometric strength of the knee extensors. Investigators will quantify peak force, rate of force development, endurance of knee extensors at 50 % of the maximal force, and the force recovery after a fatiguing protocol.

Study Design

Study Type:

Interventional

Actual Enrollment :

20 participants

Allocation:

Randomized

Intervention Model:

Crossover Assignment

Masking:

Triple (Participant, Investigator, Outcomes Assessor)

Primary Purpose:

Other

Official Title:

Acute Effects of Beetroot Juice Ingestion on Isometric Knee Extension Strength, Explosive Strength and Local Muscular Endurance

Actual Study Start Date :

Oct 1, 2022

Actual Primary Completion Date :

Oct 15, 2022

Actual Study Completion Date :

Oct 17, 2022

Arms and Interventions

Arm	Intervention/Treatment
Experimental: Experimental condition, receiving beetroot juice supplement Participants will receive beetroot juice intervention in the experimental condition.	Dietary Supplement: Beetroot juice concentrate (140 ml) A beetroot juice concentrate (140 ml) will be administered to participants in experimental conditions.
Placebo Comparator: Placebo condition Participants will receive placebo (blackcurrant juice) in the placebo condition	Dietary Supplement: Blackcurrant juice (placebo) 140 ml of blackcurrant juice with added appropriate amount of sugar to equalize the carbohydrate value and lemon juice fort the taste.

Arm

Intervention/Treatment

Experimental: Experimental condition, receiving beetroot juice supplement

Participants will receive beetroot juice intervention in the experimental condition.

Dietary Supplement: Beetroot juice concentrate (140 ml)

A beetroot juice concentrate (140 ml) will be administered to participants in experimental conditions.

Placebo Comparator: Placebo condition

Participants will receive placebo (blackcurrant juice) in the placebo condition

Dietary Supplement: Blackcurrant juice (placebo)

140 ml of blackcurrant juice with added appropriate amount of sugar to equalize the carbohydrate value and lemon juice fort the taste.

Outcome Measures

Primary Outcome Measures

Knee extension strength [2 hours after the ingestion of beetroot juice or placebo]
The peak force during maximal voluntary contraction of knee extensors

Secondary Outcome Measures

Knee extension explosive strength [2 hours after the ingestion of beetroot juice or placebo]
The rate of force development during maximal voluntary contraction of knee extensors
Knee extension local muscle endurance [2 hours after the ingestion of beetroot juice or placebo]
Time to failure of knee muscles at 50 % of maximal force

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 30 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Age between 18 and 30 years
Physically active and healthy athletes (recreational or professional)

Exclusion Criteria:

Cardiovascular, pulmonary, metabolic, neurological diseases and musculoskeletal injuries
Smokers
Consumption of drugs such as antacids and proton pump inhibitors in the previous 3 months
Pregnant or breastfeeding women
Beetroot allergic participants

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	University of Primorska Faculty of Health Sciences	Izola		Slovenia	SI-6310

Sponsors and Collaborators

University of Primorska

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Zala Jenko Praznikar, Associate Professor, University of Primorska

ClinicalTrials.gov Identifier:

NCT05567926

Other Study ID Numbers:

BEETROOT

First Posted:

Oct 5, 2022

Last Update Posted:

Oct 19, 2022

Last Verified:

Oct 1, 2022

Individual Participant Data (IPD) Sharing Statement:

Undecided

Plan to Share IPD:

Undecided

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Keywords provided by Zala Jenko Praznikar, Associate Professor, University of Primorska

isometric strength

beetroot

nitrates

local muscle endurance

supplementation

Study Results

No Results Posted as of Oct 19, 2022