Changes in Brain Activity During Mirror Therapy and Virtual Reality Therapy

Sponsor

Charles University, Czech Republic (Other)

Overall Status

Active, not recruiting

CT.gov ID

NCT05219682

Collaborator

(none)

Enrollment

Location

Anticipated Duration (Months)

2.9

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The purpose of this study is to compare electroencephalographic activity in upper limb rehabilitation with mirror therapy and virtual reality rehabilitation.

Condition or Disease	Intervention/Treatment	Phase
Healthy Age of Probands 18 - 55 Years	Other: electroencephalographic measurement	N/A

Detailed Description

This is an experiment measuring EEG to healthy adult probands during mirror therapy and VR mirroring therapy in the upper limb. The experiment will be supplemented by haptic contact and stimulation of the upper limb with a foam roller. According to the instructions, the participants will perform a predetermined movement with one upper limb - clenching the fist. In one part with the mirror, in the other part the sensor for sensing the movement of the hand detects the movement, the software creates the illusion that the patient performs the same movement with the dominant and non-dominant upper limb. The patient sees on the screen the illusion of movement of both of his upper limbs. During therapy, the other upper limb will be tactively stimulated haptically and with a foam roller. Data collection will take place by measuring the electrical activity of the brain using an EEG device. The obtained data will then be processed and evaluated with the help of the sLORETA program. The aim of this work is to compare the brain activity from the above therapies with the resting state of the proband and to focus on the activity of mirror neurons.

Study Design

Study Type:

Interventional

Anticipated Enrollment :

20 participants

Allocation:

N/A

Intervention Model:

Single Group Assignment

Intervention Model Description:

Each participant started with EEG measurements at rest followed by 3 EEG measurements in mirror therapy and 3 EEG measurements with mirror therapy in virtual reality. The order of measurement was randomized.Each participant started with EEG measurements at rest followed by 3 EEG measurements in mirror therapy and 3 EEG measurements with mirror therapy in virtual reality. The order of measurement was randomized.

Masking:

None (Open Label)

Primary Purpose:

Basic Science

Official Title:

Changes in Brain Activity in Tactile Stimulus Therapy and Ruka Ruk Therapy Compared to Mirror Therapy in Upper Limb Rehabilitation.

Actual Study Start Date :

Sep 1, 2021

Actual Primary Completion Date :

Nov 11, 2021

Anticipated Study Completion Date :

Apr 1, 2022

Outcome Measures

Primary Outcome Measures

Comparison of EEG for each intervention versus the resting phase of the measurement [month]
After processing the data in the sLORETA program, statistically significant places with different brain activity during interventions were identified, each type of intervention is evaluated separately.

Secondary Outcome Measures

Comparison of electroencephalographic recordings from mirror therapy with therapy in virtual reality [month]
After processing the data in the sLORETA program, statistically significant places with different brain activity during interventions were identified, each type of intervention is evaluated separately.

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 55 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

a healthy individual with a valid medical examination.

Exclusion Criteria:

Having a stroke or other illness that is related to a disorder of movement of the upper limbs. Severe visual or auditory deficit and decompensated epilepsy due to screen movement tracking. Persons with acute (especially infectious) diseases did not participate in the research.

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Faculty of Physical Education and Sport at Charles University	Prague		Czechia	162 52

Sponsors and Collaborators

Charles University, Czech Republic

Investigators

Study Director: MUDr. David Pánek, Ph.D., Employee

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Kateřina Pilátová, Bc., Charles University, Czech Republic

ClinicalTrials.gov Identifier:

NCT05219682

Other Study ID Numbers:

200/2020

First Posted:

Feb 2, 2022

Last Update Posted:

Feb 2, 2022

Last Verified:

Jan 1, 2022

Individual Participant Data (IPD) Sharing Statement:

Undecided

Plan to Share IPD:

Undecided

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Keywords provided by Kateřina Pilátová, Bc., Charles University, Czech Republic

Study Results

No Results Posted as of Feb 2, 2022