ARM: Does the Ingestion of Mycoprotein Elicit an Optimal Anabolic Response in Resting and Exercised Skeletal Muscle?

Sponsor

University of Exeter (Other)

Overall Status

Active, not recruiting

CT.gov ID

NCT02984345

Collaborator

(none)

Enrollment

Location

Arms

63.1

Anticipated Duration (Months)

0.3

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The present study will seek to quantify the muscle protein synthetic response to mycoprotein feeding, comparing it to milk protein as a gold standard and heavily researched positive control

Condition or Disease	Intervention/Treatment	Phase
Healthy	Other: Mycoprotein beverage Other: Milk protein beverage	N/A

Study Design

Study Type:

Interventional

Anticipated Enrollment :

20 participants

Allocation:

Randomized

Intervention Model:

Parallel Assignment

Masking:

Single (Investigator)

Primary Purpose:

Basic Science

Official Title:

Does the Ingestion of Mycoprotein Elicit an Optimal Anabolic Response in Resting and Exercised Skeletal Muscle?

Actual Study Start Date :

Jan 26, 2017

Actual Primary Completion Date :

May 1, 2018

Anticipated Study Completion Date :

May 1, 2022

Arms and Interventions

Arm	Intervention/Treatment
Active Comparator: Mycoprotein beverage	Other: Mycoprotein beverage Mycoprotein protein beverage
Placebo Comparator: Milk protein beverage	Other: Milk protein beverage Milk protein beverage

Arm

Intervention/Treatment

Active Comparator: Mycoprotein beverage

Other: Mycoprotein beverage

Mycoprotein protein beverage

Placebo Comparator: Milk protein beverage

Other: Milk protein beverage

Milk protein beverage

Outcome Measures

Primary Outcome Measures

Muscle fractional synthetic rate (muscle protein synthesis) [7.5 hours]

Secondary Outcome Measures

Plasma amino acid concentration [7.5 hours]
Serum insulin concentration [7.5 hours]
Molecular markers of muscle anabolism [7.5 hours]

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 40 Years

Sexes Eligible for Study:

Male

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

• BMI between 18 and 30 -

Exclusion Criteria:

Any diagnosed metabolic impairment (e.g. type 1 or 2 Diabetes)
Any diagnosed cardiovascular disease or hypertension.
Elevated blood pressure at the time of screening (e.g. blood pressure of ≥140/90mmHg).
Chronic use of any prescribed or over the counter pharmaceuticals.
A personal or family history of epilepsy, seizures or schizophrenia.
Anyone with previous motor disorders.
An allergy to mycoprotein / Quorn, penicillin, or milk.

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	University of Exeter, Sports & Health Sciences, College of Life & Environmental Sciences	Exeter	Devon	United Kingdom	EX1 2LU

Sponsors and Collaborators

University of Exeter

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

University of Exeter

ClinicalTrials.gov Identifier:

NCT02984345

Other Study ID Numbers:

660065600

First Posted:

Dec 6, 2016

Last Update Posted:

May 26, 2021

Last Verified:

May 1, 2021

Individual Participant Data (IPD) Sharing Statement:

Plan to Share IPD:

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Additional relevant MeSH terms:

Caseins

Study Results

No Results Posted as of May 26, 2021