Glycemic Index of Longan Syrup in Healthy Volunteers

• Sponsor: Chulalongkorn University (Other)
• Overall Status: Unknown status
• CT.gov ID: NCT04313543
• Collaborator: (none)
• Enrollment: 20
• Arm: 1
• Anticipated Duration (Months): 11.3

Study Details

Study Description

Brief Summary

Volunteers take 50 g of glucose in 250 ml of water in 5 minutes.Then, they are tested blood glucose levels (taken from the fingertips) at 15, 30 ,45, 60, 90, and 120 minutes. There is 3 days for wash out period. These tests will be repeated for 3 times for baseline glucose calculation. After that, volunteers take 50 g of longan syrup in 250 ml of water in 5 minutes.Then, they are tested blood glucose levels (taken from the fingertips) at 15, 30 ,45, 60, 90, and 120 minutes. Glycemic index of longan syrup is calculated from area under the curved of blood glucose after longan syrup taking divided to mean of area under the curved of blood glucose after glucose taking.

Condition or Disease	Intervention/Treatment	Phase
Healthy	Dietary Supplement: Glucose and Longan syrup	N/A

Study Design

• Study Type: Interventional
• Anticipated Enrollment: 20 participants
• Allocation: N/A
• Intervention Model: Single Group Assignment
• Masking: None (Open Label)
• Primary Purpose: Supportive Care
• Official Title: Determination of Glycemic Index of Longan Syrup in Healthy Volunteers
• Anticipated Study Start Date: Mar 24, 2020
• Anticipated Primary Completion Date: Feb 28, 2021
• Anticipated Study Completion Date: Mar 3, 2021

Arms and Interventions

Arm

Intervention/Treatment

Experimental: Glucose and Longan syrup Volunteers take 50 g of glucose in 250 ml of water in 5 minutes.Then, they are tested blood glucose levels (taken from the fingertips) at 15, 30 ,45, 60, 90, and 120 minutes. There is 3 days for wash out period. These tests will be repeated for 3 times for baseline glucose calculation. After that, volunteers take 50 g of longan syrup in 250 ml of water in 5 minutes.Then, they are tested blood glucose levels (taken from the fingertips) at 15, 30 ,45, 60, 90, and 120 minutes. Glycemic index of longan syrup is calculated from area under the curved of blood glucose after longan syrup taking divided to mean of area under the curved of blood glucose after glucose taking

Dietary Supplement: Glucose and Longan syrup; Volunteers take 50 g of glucose in 250 ml of water in 5 minutes. Then, they take 50g of longan syrup in 250 ml of water in 5 minutes

Outcome Measures

Primary Outcome Measures

1. Blood glucose [Change from glucose baseline in 120 minutes]

   They are tested blood glucose levels (taken from the fingertips) at 15, 30 ,45, 60, 90, and 120 minutes. There is 3 days for wash out period. These tests will be repeated for 3 times for baseline glucose calculation.

Secondary Outcome Measures

1. Adverse events [12 days]

   Number of participants with skin, respiratory, and gastrointestinal side effects

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 60 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

• Ages 18-60 years

• Never diagnosis as diabetes mellitus of thyroid dysfunction

• Fasting plasma glucose less than 100 mg/dl

• Body mass index 18.5-24.9 kg/m2

• Be willing to be subjects in this study

Exclusion Criteria:

• Know longan allergy or have history of adverse events from longan

• Take medicines, herbs, or food supplements including thiazide diuretics, beta-blockers ,and estrogen that have an effect on blood sugar level in 1 month before this study starting

• Severe comorbidity or uncontrolled diseases

• Pregnancy and lactation

• Participated in other studies

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

• Chulalongkorn University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Pornanong Aramwit, Pharm.D., Ph.D, Professor, Chulalongkorn University
• ClinicalTrials.gov Identifier: NCT04313543
• Other Study ID Numbers: 827/62
• First Posted: Mar 18, 2020
• Last Update Posted: Mar 18, 2020
• Last Verified: Mar 1, 2020

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Keywords provided by Pornanong Aramwit, Pharm.D., Ph.D, Professor, Chulalongkorn University: Longan; Glycemic; Glucose

Study Results

No Results Posted as of Mar 18, 2020