Compare the Effects of Agility and Cycling Exercise Training on Mobility and Balance in PD and Healthy Old Adults

Sponsor

Somogy Megyei Kaposi Mór Teaching Hospital (Other)

Overall Status

Completed

CT.gov ID

NCT03427762

Collaborator

University of Groningen (Other)

Enrollment

Location

Arms

3.2

Actual Duration (Months)

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The purpose of the study is to compare the effectiveness and specificity of agility and cycling exercise training on balance and mobility outcomes in PD and age and gender matched healthy controls. The hypothesis is that due to being profoundly deconditioned, agility and cycling will be similarly effective in PD but agility will be more effective then cycling in healthy old adults, in improving mobility and balance.

Condition or Disease	Intervention/Treatment	Phase
Healthy Movement Disorders Parkinson Disease Condition	Other: Rehabilitation	N/A

Study Design

Study Type:

Interventional

Actual Enrollment :

3 participants

Allocation:

Randomized

Intervention Model:

Parallel Assignment

Masking:

None (Open Label)

Primary Purpose:

Treatment

Official Title:

Compare the Effects of Agility and Cycling Exercise Training on Mobility and Balance in PD and Healthy Old Adults

Actual Study Start Date :

Feb 3, 2018

Actual Primary Completion Date :

Apr 15, 2018

Actual Study Completion Date :

May 10, 2018

Arms and Interventions

Arm	Intervention/Treatment
Experimental: Healthy cycling group During a 5-week intervention, we examine the patients' balance, postural control, quality of life and mobility. Then there is a bicycle every 1 hour.	Other: Rehabilitation Healthy cycling group: The group participates in 5 weeks of intensive cycling therapy. Healthy xbox group: The group participates in 5 week intensive xbox therapy Healthy controll group: The group does not take any kind of therapy. PD group: We have already analyzed the results of our group, and we will compare their results with the results of healthy groups. Other Names: Healthy cycling group Healthy xbox group PD group
Experimental: Healthy xbox group During a 5-week intervention, we examine the patients' balance, postural control, quality of life and mobility. Then they will train 1 hour every day on an xbox program.	Other: Rehabilitation Healthy cycling group: The group participates in 5 weeks of intensive cycling therapy. Healthy xbox group: The group participates in 5 week intensive xbox therapy Healthy controll group: The group does not take any kind of therapy. PD group: We have already analyzed the results of our group, and we will compare their results with the results of healthy groups. Other Names: Healthy cycling group Healthy xbox group PD group
No Intervention: Healthy controll group During a 5-week intervention, we examine the patients' balance, postural control, quality of life and mobility. Thereafter, the group does not move only in everyday life.
Experimental: PD groupe Patients with PD have already been evaluated and compared to the results of a healthy group within a separate experiment. The study and the results have been completed. Clinical trial number:NCT03193268	Other: Rehabilitation Healthy cycling group: The group participates in 5 weeks of intensive cycling therapy. Healthy xbox group: The group participates in 5 week intensive xbox therapy Healthy controll group: The group does not take any kind of therapy. PD group: We have already analyzed the results of our group, and we will compare their results with the results of healthy groups. Other Names: Healthy cycling group Healthy xbox group PD group

Outcome Measures

Primary Outcome Measures

Postural instability [5 weeks]
Body sway (mm) (Posturography test)
quality of life [5 weeks]
EQ-5D (EQ-5D was first introduced in 1990 by the EuroQol Group, The EQ-5D questionnaire is made up for two components; health state description and evaluation)
balance test [5 weeks]
Berg Balance test (The Berg Balance Scale (BBS) was developed to measure balance among older people with impairment in balance function by assessing the performance of functional tasks, 41-56 = low fall risk, 21-40 = medium fall risk, 0 -20 = high fall risk )
mobility test [5 weeks]
Six minutes walk test (6MWT) (m) (The six-minute walk test (6MWT) measures the distance an individual is able to walk over a total of six minutes on a hard, flat surface. The goal is for the individual to walk as far as possible in six minutes. The individual is allowed to self-pace and rest as needed as they traverse back and forth along a marked walkway)

Secondary Outcome Measures

depression scale [5 weeks]
Beck Depression scale (The Beck Depression Inventory (BDI) is a 21-item, self-report rating inventory that measures characteristic attitudes and symptoms of depression, 0-13: minimal depression, 14-19: mild depression, 20-28: moderate depression, 29-63: severe depression)