Hemangioma Growth During the First 6 Months of Life

Sponsor
University of California, San Francisco (Other)
Overall Status
Completed
CT.gov ID
NCT00911781
Collaborator
Mayo Clinic (Other), Medical College of Wisconsin (Other)
36
2
33.9
18
0.5

Study Details

Study Description

Brief Summary

One of the most important and unique characteristics of infantile hemangiomas is their dramatic growth during early infancy. Most hemangiomas are either absent at birth or barely evident as a small scratch or bruise-like area. A recent study emphasized how early hemangioma growth occurs. In this study by 3 months of age, hemangiomas had reached 80% of their final size, and by 5 months of age, 80% had already stopped growing. Unfortunately the average age when most infants are seen by specialists is often at 5 months of age or later, a time when most growth is already completed.

Researchers at the University of California, San Francisco, the Medical College of Wisconsin, and at the Mayo Clinic are interested in studying hemangioma growth at even earlier ages, before 3 months of age, which is before most patients are ever seen by dermatologists or other specialists. For this study are requesting that parents of children older than 3 months of age with hemangiomas send us a series of photographs of their child which demonstrates this early growth. Ideally the photographs would show your child (including the area of the hemangioma of course) at weekly or every other week intervals up until age least 3 to 6 months of age. This will probably not be difficult if the hemangioma is on the face but we would be interested in other body locations as well, if available.

We are using these photographs to analyze early hemangioma growth patterns, to see if there is a period of especially rapid growth, and to help determine if there is a specific time before which specialty referral should occur. We are interested in all sizes of hemangiomas, from small to large. Of greatest importance is that the photos be at frequent intervals (every 1 to 2 weeks is ideal) and of sufficient quality to be able to evaluate the appearance of the hemangioma.

Condition or Disease Intervention/Treatment Phase
  • Other: No intervention

Study Design

Study Type:
Observational
Actual Enrollment :
36 participants
Observational Model:
Cohort
Time Perspective:
Retrospective
Official Title:
Hemangioma Growth During the First 6 Months of Life
Study Start Date :
Feb 1, 2009
Actual Primary Completion Date :
May 1, 2011
Actual Study Completion Date :
Dec 1, 2011

Arms and Interventions

Arm Intervention/Treatment
Infants with infantile hemangiomas

Other: No intervention
We are only asking for photographs from parents.

Outcome Measures

Primary Outcome Measures

  1. hemangioma growth [up to 8 weeks]

Eligibility Criteria

Criteria

Ages Eligible for Study:
3 Months to 5 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • Children older than 3 months of age who have or have had a diagnosis of an infantile hemangioma. The parents of these children will be able to provide us with frequent (weekly to biweekly) photographs of the patient's hemangioma(s) during the first 3-6 months of life.

  • These hemangiomas must have a superficial component that can be seen. Parents must consent to the use of their child's photographs in this study.

Exclusion Criteria:
  • Current age less than 3 months. Patient who do not have an infantile hemangioma (as determined by the investigators). Patients whose photographs are not of sufficient quality or frequency in order to be evaluated for this study.

Contacts and Locations

Locations

Site City State Country Postal Code
1 University of California, San Francisco San Francisco California United States 94115
2 Mayo Clinic Rochester Minnesota United States 55901

Sponsors and Collaborators

  • University of California, San Francisco
  • Mayo Clinic
  • Medical College of Wisconsin

Investigators

  • Principal Investigator: Ilona J Frieden, MD, University of California, San Francisco

Study Documents (Full-Text)

None provided.

More Information

Additional Information:

Publications

Responsible Party:
University of California, San Francisco
ClinicalTrials.gov Identifier:
NCT00911781
Other Study ID Numbers:
  • hemangioma photo study
First Posted:
Jun 2, 2009
Last Update Posted:
Feb 5, 2013
Last Verified:
Feb 1, 2013
Keywords provided by University of California, San Francisco
Additional relevant MeSH terms:

Study Results

No Results Posted as of Feb 5, 2013