FEATHERSv2: VR Error Augmentation for Bimanual Task Exercise

Sponsor
University of British Columbia (Other)
Overall Status
Completed
CT.gov ID
NCT03766711
Collaborator
Kids Brain Health Network (Other)
5
2
2
20.4
2.5
0.1

Study Details

Study Description

Brief Summary

This project is a continuing study from the FEATHERS project (NCT02290353) which focuses on developing novel home therapy program for persons with hemiparesis. This study will focus on examining motor behaviour and adaptation in neurodevelopmental hemiparesis (cerebral palsy, acquired brain injury (ABI)). New algorithms for motion control involved in encouraging active movement are developed and will be tested, but the study has the same therapeutic goal and focus as the original FEATHERS project of creating an engaging at-home bimanual upper limb training program. By incorporating existing gaming technology, we hope to discover novel ways to adapt commercial motion tracking controllers and visual feedback into engaging rehabilitative learning tools. This study will focus on a basic science aspect of human bimanual movements that can be incorporated into future applications of the full FEATHERS project devices. We believe that together these approaches will yield interventions that significantly improve functional ability and lead to improved quality of life.

Condition or Disease Intervention/Treatment Phase
  • Other: Physical Therapy
N/A

Detailed Description

(Main Phase Only - Data Collected with Clinical Population)

The FEATHERS project at the RREACH Lab at The University of British Columbia focuses on developing and evaluating novel physical exercise technologies for kids with motor disabilities. The study team would like to study how immersive virtual reality (VR) technology can be used to benefit upper limb rehabilitation for persons with hemiplegia. The purpose of the experiment is to see how the use of error augmentation (i.e. adding visual or game element feedback to accentuate deviation from the desired exercise motion) might encourage persons with hemiplegia to engage their affected side more effectively by comparing the symmetry between the stronger and weaker limbs. It is also hypothesized that the immersive environment of VR and the ability to provide 1:1 direct visual feedback will increase active engagement to rehabilitative exercises in these populations. The study will address the question of whether error augmentation aids in the rehabilitation of the affected upper limb movement quality in hemiparesis when practicing bilateral reaching tasks. Specifically, can visual amplification of paretic asymmetry in an immersive VR environment improve movement quality in the affected side?

Adolescents and young adults with hemiplegia (i.e. due to ABI, CP, etc.) and their adjoining therapists will be recruited for from the community. We will conduct testing in a single-session setup at the participant chosen location with an easily transportable system including a standard 2-3 sensor Oculus system hardware setup and software developed by the research team. Sessions conducted outside the research lab rooms will require a minimum of a 2m x 1.5m space for calibration. The participants will test all augmentation factors in a randomized order and the sessions are expected to take between 90-120 minutes. A short post-session usability survey will be administered and sample population demographic data will be recorded including age, gender, and handedness. Manual Ability Classification System (MACS) and Bimanual Fine Motor Function (BFMF) scores will be recorded or assessed to classify the upper limb motor ability of the sample set.

Study Design

Study Type:
Interventional
Actual Enrollment :
5 participants
Allocation:
Randomized
Intervention Model:
Crossover Assignment
Masking:
Single (Participant)
Masking Description:
Participant intervention arm will be randomized and they will not be told which whether the treatment is being applied in the current set. However, they will be instructed of the task goal at the beginning of the session and will be told that we will be modifying visual feedback to help improve reaching symmetry in some manner.
Primary Purpose:
Basic Science
Official Title:
FEATHERS 2.0: Functional Engagement in Assistive Therapy Through Exercise Robotics v2.0
Actual Study Start Date :
Jan 10, 2018
Actual Primary Completion Date :
Mar 30, 2019
Actual Study Completion Date :
Sep 24, 2019

Arms and Interventions

Arm Intervention/Treatment
Experimental: Actual - Augmented

Reaching task as a physical therapy intervention. First with 1:1 visual feedback, then with augmented forward symmetry.

Other: Physical Therapy
Repetitive bimanual task training for upper limb motor function recovery.

Experimental: Augmented - Actual

Reaching task as a physical therapy intervention. First with augmented forward symmetry, then with 1:1 visual feedback.

Other: Physical Therapy
Repetitive bimanual task training for upper limb motor function recovery.

Outcome Measures

Primary Outcome Measures

  1. Change in Error in Forward Reaching Symmetry [Recorded per reach, throughout the session (about 2 hours)]

    Compared between each condition (in cm, % change from baseline)

Secondary Outcome Measures

  1. Distance traveled of each arm from head [Recorded per reach, throughout the session (about 2 hours)]

    Change in position in cm of the participant hands from the start to end of the reach trial

  2. Time to complete task [Recorded per reach, throughout the session (about 2 hours)]

    Time in seconds from the start to the end of the reach trial

  3. Movement Smoothness [Recorded per arm, per reach, throughout the session (about 2 hours)]

    Deviation from linear path in the lateral direction and number of peaks in forward velocity profile

  4. Change in Error in Forward Reaching Symmetry Over Time [Recorded per reach, throughout the session (about 2 hours)]

    Change in error throughout each set during the learning conditions

  5. Compensation Techniques Causing Joint Asymmetry [Recorded throughout the session (about 2 hours)]

    Maximum difference in cm in contralateral joint position in the upper body (shoulder y, z)

  6. Trunk Compensation [Recorded throughout the session (about 2 hours)]

    Change in forward position in cm of the participant head and trunk (mid-shoulder point) during reaching movement

Eligibility Criteria

Criteria

Ages Eligible for Study:
13 Years to 21 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion for adolescents and young adults (ages 13-21 years) :
  1. Hemiplegia as a result of a neurological impairment (CP, ABI, paediatric stroke, etc.)

  2. Use both eyes and visually interact using a stereoscopic device that allows a minimum interpupillary distance of 58mm

  3. Comfortably support regular head motion while wearing a 470g head-mounted display

  4. Ability to lift arms against gravity at least some distance away from their body (some shoulder and elbow flexion and extension) as reported by participant, consenting guardian, or adjoining therapist

  5. Ability to stand or sit independently for 15 minutes at a time in a chair without arm supports for a total of up to 120 minutes

  6. Ability to follow instructions and verbally communicate in basic English (as determined by referring therapist)

Exclusion Criteria:
  1. Upper limb orthopedic surgery in the past six months

  2. Known susceptibility to cybersickness

Contacts and Locations

Locations

Site City State Country Postal Code
1 Physiotherapy, BC Children's Hospital Vancouver British Columbia Canada V6H 3V4
2 RREACH Lab, The University of British Columbia Vancouver British Columbia Canada V6T 1Z4

Sponsors and Collaborators

  • University of British Columbia
  • Kids Brain Health Network

Investigators

  • Principal Investigator: Hendrik FM Van der Loos, PhD, P.Eng, The University of British Columbia

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Hendrik F. Machiel Van der Loos, Associate Professor, Dept. Mechanical Engineering, University of British Columbia
ClinicalTrials.gov Identifier:
NCT03766711
Other Study ID Numbers:
  • H17-01126
First Posted:
Dec 6, 2018
Last Update Posted:
Nov 2, 2020
Last Verified:
Oct 1, 2020
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Hendrik F. Machiel Van der Loos, Associate Professor, Dept. Mechanical Engineering, University of British Columbia
Additional relevant MeSH terms:

Study Results

No Results Posted as of Nov 2, 2020